{"id":18,"date":"2020-11-26T12:26:23","date_gmt":"2020-11-26T03:26:23","guid":{"rendered":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/immunol\/?page_id=18"},"modified":"2026-03-11T19:37:48","modified_gmt":"2026-03-11T10:37:48","slug":"publications","status":"publish","type":"page","link":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/immunol\/publications\/","title":{"rendered":"\u7814\u7a76\u696d\u7e3e"},"content":{"rendered":"<h3>2026\u5e74<\/h3>\n<ul>\n<li>Nakanishi K, Yukishima K,\u00a0<b>Umemoto E. <\/b>The potential of GPR31 as a target for effective oral vaccination (Editorial). <strong><em>Expert Opin Ther Targets. <\/em><\/strong>8:1-4. 2026. doi: 10.1080\/14728222.2026.2641654<\/li>\n<\/ul>\n<h3>2025\u5e74<\/h3>\n<ul>\n<li>Tomii K, Ozawa M, Kanda Y, Kobayashi D, Li NJ,\u00a0<b>Umemoto E<\/b>, Hayasaka H, Tomura M, Takeuchi A, Abe R, Katakai T. Squaric Acid Dibutylester Promotes Innate Immune-Driven Hair Growth with CD206<sup>+<\/sup> Macrophage Accumulation in the Dermis. <em><strong>JID Innov.<\/strong><\/em> 6(1):100420. 2025. doi: 10.1016\/j.xjidi.2025.100420.<\/li>\n<li>Okamura Y, Nakanishi K, Inada R, Maeda R, Maeshima K, Mizutani M, Ohashi W, Ikawa M, Sugiura Y, Takeda K, <strong>Umemoto E.\u00a0<\/strong>GPR35 mediates monocyte recruitment to the sites of <em>Listeria monocytogenes. <\/em><strong><em>Cell. Mol. Life Sci<\/em><\/strong><em><em>. <\/em><\/em>82(1):433. 2025. <span style=\"letter-spacing: 0.1rem; word-spacing: normal;\">doi: 10.1007\/s00018-025-05912-5.<\/span><\/li>\n<li>Nakanishi K, Ajiro T, Yukishima K, Tsukamoto Y, Kikuta J, Sawa S, Tomura M, Kinoshita N, Shimanuki W, Suzuki A, Arai S, Maeshima K, Ichisawa T, Katakai T, Hayasaka H, Ishii M,\u00a0<b>Umemoto E. <\/b>Pyruvate-GPR31 axis induces LysoDC dendrite protrusion to M-cell pockets for effective immune responses. <strong><em>Gut Microbes.<\/em>\u00a0<\/strong> 17:2536089. 2025 doi: 10.1080\/19490976.2025.2536089.<\/li>\n<li>Nonaka D, Yoshida S, Nakano K, Li X, Okamura T,\u00a0<b>Umemoto E<\/b>, Yamada T, Watanabe M, Jinno S, Ito M, Tsuda M, Noguchi N, Jiang JX, Sumiya E, Sawa S. Fibroblast-derived CSF1 maintains colonization of gut mucosal macrophage to resist bacterial infection. <strong><em>Mucosal Immunol.<\/em><\/strong>\u00a0 S1933-0219(25)00071-6. 2025. doi: 10.1016\/j.mucimm.2025.06.011.<\/li>\n<li>Hirano K, Nakabayashi C, Sasaki M, Suzuki M, Aoyagi Y, Tanaka K, Murakami A, Tsuchiya M,\u00a0<b>Umemoto E<\/b>, Takabayashi S, Kitajima Y, Ono Y, Matsukawa T, Matsushita M, Ohkawa Y, Mori Y, Hara Y. Mg<sup>2+<\/sup> influx mediated by TRPM7 triggers the initiation of muscle stem cell activation. <strong><em>Sci Adv.<\/em> <\/strong>11(14):eadu0601. 2025 doi: 10.1126\/sciadv.adu0601.<\/li>\n<\/ul>\n<h3>2024\u5e74<\/h3>\n<ul>\n<li>Oguro-Igashira E, Murakami M, Mori R, Kuwahara R, Kihara T, Kohara M, Fujiwara M, Motooka D, Okuzaki D, Arase M, Toyota H, Peng S, Ogino T, Kitabatake Y, Morii E, Hirota S, Ikeuchi H,\u00a0<b>Umemoto E<\/b>, Kumanogoh A, Takeda K. The pyruvate-GPR31 axis promotes transepithelial dendrite formation in human intestinal dendritic cells. <strong><em>Proc Natl Acad Sci USA.<\/em><\/strong> 121:e2318767121. 2024 doi: 10.1073\/pnas.2318767121.<\/li>\n<\/ul>\n<h3>2023\u5e74<\/h3>\n<ul>\n<li>Kobayashi D,\u00a0<b>Umemoto E<\/b>, Miyasaka M. The role of extracellular ATP in homeostatic immune cell migration. <em><strong>Curr Opin Pharmacol.<\/strong> <\/em>68:102331. 2023<\/li>\n<\/ul>\n<h3>2022\u5e74<\/h3>\n<ul>\n<li>Liu Q,\u00a0<b>Umemoto E<\/b>, Morita N, Kayama H, Baba Y, Kurosaki T, Okumura R, Takeda K. Pyruvate enhances oral tolerance via GPR31.<strong><em> Int Immunol. <\/em><\/strong>34:343-352.2022<\/li>\n<li><strong>Nakanishi K,<\/strong> Takase T, Ohira Y, Ida R, Mogi N, Kikuchi Y, Matsuda M, <strong>Kurohane K,<\/strong> Akimoto Y, Hayakawa J, Kawakami H, Niwa Y, Kobayashi H,\u00a0<b>Umemoto E<\/b>, Imai Y. <strong><em>Sci Rep.<\/em> <\/strong>12:17999. 2022<\/li>\n<li>Hirano K, Tsuchiya M, Shiomi A, Takabayashi S, Suzuki M, Ishikawa Y, Kawano Y, Takabayashi Y, Nishikawa K, Nagao K,\u00a0<b>Umemoto E<\/b>, Kitajima Y, Ono Y, Nonomura K, Shintaku H, Mori Y, Umeda M, Hara Y. <em><strong>Life Sci Alliance.<\/strong><\/em> 6:e202201783. 2022<\/li>\n<\/ul>\n<h3>2021\u5e74<\/h3>\n<ul>\n<li>Kobayashi D, Sugiura Y,\u00a0<b>Umemoto E<\/b>, Takeda A, Ueta H, Hayasaka H, Matsuzaki S, Katakai T, Suematsu M, Hamachi I, Yegutkin GG, Salmi M, Jalkanen S, Miyasaka M. Extracellular ATP Limits Homeostatic T Cell Migration Within Lymph Nodes. <em><strong>Front Immunol.<\/strong><\/em> 12:786595, 2021<\/li>\n<\/ul>\n<h3>2020\u5e74<\/h3>\n<ul class=\"list\">\n<li>Takahashi D, Hoshina N, Kabumoto Y, Maeda Y, Suzuki A, Tanabe H, Isobe J, Yamada T, Muroi K, Yanagisawa Y, Nakamura A, Fujimura Y, Saeki A, Ueda M, Matsumoto R, Asaoka H, Clarke JM, Harada Y, <strong>Umemoto E,<\/strong> Komatsu N, Okada T, Takayanagi H, Takeda K, Tomura M, Hase K. Microbiota-derived butyrate limits the autoimmune response by promoting the differentiation of follicular regulatory T cells. <strong><em>EBioMedicine.<\/em><\/strong> 58:102913, 2020<\/li>\n<li>Sakaguchi T, Okumura R, Ono C, Okuzaki D, Kawai T, Okochi Y, Tanimura N, Murakami M, Kayama H, <strong>Umemoto E,<\/strong> Kioka H, Ohtani T, Sakata Y, Miyake K, Okamura Y, Baba Y, Takeda K. TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes. <strong><em>Cell Rep. <\/em><\/strong>31:107755, 2020<\/li>\n<li>Okochi Y, <strong>Umemoto E, <\/strong>Okamura Y. Hv1\/VSOP regulates neutrophil directional migration and ERK activity by tuning ROS production.<strong> <em>J Leukoc Biol. <\/em><\/strong>107:819-831, 2020<\/li>\n<\/ul>\n<h3>2019\u5e74<\/h3>\n<ul class=\"list\">\n<li>Simmons S, Sasaki N, <strong>Umemoto E,<\/strong> Uchida Y, Fukuhara S, Kitazawa Y, Okudaira M, Inoue A, Tohya K, Aoi K, Aoki J, Mochizuki N, Matsuno K, Takeda K, Miyasaka M, Ishii M. High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node. <strong><em>eLife.<\/em><\/strong> 8:e41239, 2019<\/li>\n<li>*Morita N, <strong>*Umemoto E,<\/strong> Fujita S, Hayashi A, Kikuta J, Kimura I, Haneda T, Imai T, Inoue A, Mimuro H, Maeda Y, Kayama H, Okumura R, Aoki J, Okada N, Kida T, Ishii M, Nabeshima R, Takeda K. (* equal contribution). GPR31-dependent dendrite protrusion of intestinal CX3CR1<sup>+<\/sup> cells by bacterial metabolites. <strong><em>Nature.<\/em><\/strong> 566:110-114, 2019<\/li>\n<\/ul>\n<h3>2018\u5e74<\/h3>\n<ul class=\"list\">\n<li>Takeuchi A, Ozawa M, Kanda Y, Kozai M, Ohigashi I, Kurosawa Y, Rahman MA, Kawamura T, Shichida Y, <strong>Umemoto E, <\/strong>Miyasaka M, Ludewig B, Takahama Y, Nagasawa T, Katakai T. A Distinct Subset of Fibroblastic Stromal Cells Constitutes the Cortex-Medulla Boundary Subcompartment of the Lymph Node. <strong><em>Front Immunol.<\/em><\/strong> 9:2196, 2018<\/li>\n<li>Takeda A, Miyasaka M, <strong>Umemoto E. <\/strong>Two-Photon Imaging of T-Cell Motility in Lymph Nodes: <em>In Vivo<\/em> and<em> Ex Vivo<\/em> Approaches. <strong><em>Methods Mol Biol. <\/em><\/strong>1763:43-52, 2018;<\/li>\n<li>Ikeda M, Shimizu K, Ogura H, Kurakawa T, <strong>Umemoto E, <\/strong>Motooka D, Nakamura S, Ichimaru N, Takeda K, Takahara S, Hirano SI, Shimazu T. Hydrogen-Rich Saline Regulates Intestinal Barrier Dysfunction, Dysbiosis, and Bacterial Translocation in a Murine Model of Sepsis.<strong><em> Shock.<\/em><\/strong> 50:640-647, 2018<\/li>\n<\/ul>\n<h3>2017\u5e74<\/h3>\n<ul class=\"list\">\n<li>Ikeda K, Kinoshita M, Kayama H, Nagamori S, Kongpracha P, <strong>Umemoto E,<\/strong> Okumura R, Kurakawa T, Murakami M, Mikami N, Shintani Y, Ueno S, Andou A, Ito M, Tsumura H, Yasutomo K, Ozono K, Takashima S, Sakaguchi S, Kanai Y, Takeda K. Slc3a2 Mediates Branched-Chain Amino-Acid-Dependent Maintenance of Regulatory T Cells.<strong><em> Cell Rep.<\/em><\/strong> 21:1824-1838, 2017<\/li>\n<li>Furuta Y, Tsai SH, Kinoshita M, Fujimoto K, Okumura R, <strong>Umemoto E,<\/strong> Kurashima Y, Kiyono H, Kayama H, Takeda K. E-NPP3 controls plasmacytoid dendritic cell numbers in the small intestine. <strong><em>PLoS One.<\/em><\/strong> 12:e0172509, 2017<\/li>\n<\/ul>\n<h3>2016\u5e74<\/h3>\n<ul class=\"list\">\n<li>Maeda Y, Kurakawa T, <strong>Umemoto E,<\/strong> Motooka D, Ito Y, Gotoh K, Hirota K, Matsushita M, Furuta Y, Narazaki M, Sakaguchi N, Kayama H, Nakamura S, Iida T, Saeki Y, Kumanogoh A, Sakaguchi S, Takeda K. Dysbiosis Contributes to Arthritis Development via Activation of Autoreactive T Cells in the Intestine. <strong><em>Arthritis Rheumatol. <\/em><\/strong>68:2646-2661, 2016<\/li>\n<li>Okumura R, Kurakawa T, Nakano T, Kayama H, Kinoshita M, Motooka D, Gotoh K, Kimura T, Kamiyama N, Kusu T, Ueda Y, Wu H, Iijima H, Barman S, Osawa H, Matsuno H, Nishimura J, Ohba Y, Nakamura S, Iida T, Yamamoto M,<strong> Umemoto E, <\/strong>Sano K, Takeda K. Lypd8 promotes the segregation of flagellated microbiota and colonic epithelia. <strong><em>Nature. <\/em><\/strong>532:117-21, 2016<\/li>\n<li>Kawano H, Kayama H, Nakama T, Hashimoto T, <strong>Umemoto E,<\/strong> Takeda K. IL-10-producing lung interstitial macrophages prevent neutrophilic asthma. <strong><em>Int Immunol. <\/em><\/strong>28:489-501. 2016<\/li>\n<li>Takeda A, Kobayashi D, Aoi K, Sasaki N, Sugiura Y, Igarashi H, Tohya K, Inoue A, Hata E, Akahoshi N, Hayasaka H, Kikuta J, Scandella E, Ludewig B, Ishii S, Aoki J, Suematsu M, Ishii M, Takeda K, Jalkanen S, Miyasaka M, <strong>Umemoto E.<\/strong> Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility.<strong><em> eLife.<\/em><\/strong> 5:e10561, 2016<\/li>\n<li>Hata E, Sasaki N, Takeda A, Tohya K, <strong>Umemoto E,<\/strong> Akahoshi N, Ishii S, Bando K, Abe T, Kano K, Aoki J, Hayasaka H, Miyasaka M. Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes. <strong><em>Int Immunol.<\/em><\/strong> 28:283-292, 2016<\/li>\n<\/ul>\n<h3>2015\u5e74<\/h3>\n<ul class=\"list\">\n<li>Ishihara S, Nishikimi A, <strong>Umemoto E, <\/strong>Miyasaka M, Saegusa M, Katagiri K. Dual functions of Rap1 are crucial for T-cell homeostasis and prevention of spontaneous colitis. <strong><em>Nat Commun. <\/em><\/strong>6:8982, 2015<\/li>\n<li>Tsai SH, Kinoshita M, Kusu T, Kayama H, Okumura R, Ikeda K, Shimada Y, Takeda A, Yoshikawa S, Obata-Ninomiya K, Kurashima Y, Sato S, <strong>Umemoto E, <\/strong>Kiyono H, Karasuyama H, Takeda K. The ectoenzyme E-NPP3 negatively regulates ATP-dependent chronic allergic responses by basophils and mast cells. <strong><em>Immunity.<\/em><\/strong> 42:279-293, 2015<\/li>\n<li>Rantakari P, Auvinen K, J\u00e4ppinen N, Kapraali M, Valtonen J, Karikoski M, Gerke H, Iftakhar-E-Khuda I, Keuschnigg J, <strong>Umemoto E, <\/strong>Tohya K, Miyasaka M, Elima K, Jalkanen S, Salmi M. The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes. <strong><em>Nat Immunol.<\/em><\/strong> 16:386-396. 2015<\/li>\n<\/ul>\n<h3>2014\u5e74<\/h3>\n<ul class=\"list\">\n<li>Totsuka N, Kim YG, Kanemaru K, Niizuma K, <strong>Umemoto E,<\/strong> Nagai K, Tahara-Hanaoka S, Nakahasi-Oda C, Honda S, Miyasaka M, Shibuya K, Shibuya A. Toll-like receptor 4 and MAIR-II\/CLM-4\/LMIR2 immunoreceptor regulate VLA-4-mediated inflammatory monocyte migration.<br \/>\n<strong><em>Nat Commun.<\/em><\/strong> 5:4710, 2014<\/li>\n<li>Masahata K, <strong>Umemoto E, <\/strong>Kayama H, Kotani M, Nakamura S, Kurakawa T, Kikuta J, Gotoh K, Motooka D, Sato S, Higuchi T, Baba Y, Kurosaki T, Kinoshita M, Shimada Y, Kimura T, Okumura R, Takeda A, Tajima M, Yoshie O, Fukuzawa M, Kiyono H, Fagarasan S, Iida T, Ishii M, Takeda K. Generation of colonic IgA-secreting cells in the caecal patch. <strong><em>Nat Commun.<\/em><\/strong> 5:3704, 2014<\/li>\n<\/ul>\n<h3>2013\u5e74<\/h3>\n<ul class=\"list\">\n<li><strong>Umemoto E,<\/strong> Takeda A, Jin S, Luo Z, Nakahogi N, Hayasaka H, Lee CM, Tanaka T, Miyasaka M.Dynamic changes in endothelial cell adhesion molecule nepmucin\/CD300LG expression under physiological and pathological conditions. <strong><em>PLoS One.<\/em><\/strong> 8:e83681, 2013<\/li>\n<li>Watanabe TM, Fujii F, Jin T, <strong>Umemoto E,<\/strong> Miyasaka M, Fujita H, Yanagida T. Four-dimensional spatial nanometry of single particles in living cells using polarized quantum rods. <strong><em>Biophys J. <\/em><\/strong>105:555-64. 2013<\/li>\n<li>Kimura T, Katoh H, Kayama H, Saiga H, Okuyama M, Okamoto T, <strong>Umemoto E, <\/strong>Matsuura Y, Yamamoto M, Takeda K. Ifit1 inhibits Japanese encephalitis virus replication through binding to 5&#8242; capped 2&#8242;-O unmethylated RNA. <strong><em>J Virol. <\/em><\/strong>87:9997-10003, 2013<\/li>\n<li>*Bai Z, *Cai L, <strong>*<sup>#<\/sup>Umemoto E,<\/strong> *Takeda A, Tohya K, Komai Y, Veeraveedu PT, Hata E, Sugiura Y, Kubo A, Suematsu M, Hayasaka H, Okudaira S, Aoki J, Tanaka T, Albers HM, Ovaa H, <sup>#<\/sup>Miyasaka M. (* equal contribution, #equal correspondence). Constitutive lymphocyte transmigration across the basal lamina of high endothelial venules is regulated by the autotaxin\/lysophosphatidic acid axis.<strong><em> J Immunol. <\/em><\/strong>190:2036-2048, 2013<\/li>\n<\/ul>\n<h3>2012\u5e74\u4ee5\u524d<\/h3>\n<ul class=\"list\">\n<li><strong>Umemoto E, <\/strong>Otani K, Ikeno T, Verjan Garcia N, Hayasaka H, Bai Z, Jang MH, Tanaka T, Nagasawa T, Ueda K, Miyasaka M. Constitutive plasmacytoid dendritic cell migration to the splenic white pulp is cooperatively regulated by CCR7- and CXCR4-mediated signaling. <strong><em>J Immunol. <\/em><\/strong>2012 Jul 1;189(1):191-9.<\/li>\n<li>Verjan Garcia N, <strong>Umemoto E, <\/strong>Saito Y, Yamasaki M, Hata E, Matozaki T, Murakami M, Jung YJ, Woo SY, Seoh JY, Jang MH, Aozasa K, Miyasaka M. SIRP\u03b1\/CD172a regulates eosinophil homeostasis. <strong><em>J Immunol.<\/em><\/strong> 187:2268-22677, 2011<\/li>\n<li><strong>Umemoto E,<\/strong> Hayasaka H, Bai Z, Cai L, Yonekura S, Peng X, Takeda A, Tohya K, Miyasaka M.Novel regulators of lymphocyte trafficking across high endothelial venules. <strong><em>Crit Rev Immunol.<\/em><\/strong> 31:147-69, 2011<\/li>\n<li>Tohya K, <strong>Umemoto E, <\/strong>Miyasaka M. Microanatomy of lymphocyte-endothelial interactions at the high endothelial venules of lymph nodes. <strong><em>Histol Histopathol. <\/em><\/strong>25:781-794, 2010<\/li>\n<li>Nakasaki T, Tanaka T, Okudaira S, Hirosawa M, <strong>Umemoto E,<\/strong> Otani K, Jin S, Bai Z, Hayasaka H, Fukui Y, Aozasa K, Fujita N, Tsuruo T, Ozono K, Aoki J, Miyasaka M. Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions. <strong><em>Am J Pathol.<\/em><\/strong> 173:1566-1576, 2008<\/li>\n<li>Jin S, <strong>Umemoto E<\/strong>, Tanaka T, Shimomura Y, Tohya K, Kunizawa K, Yang BG, Jang MH, Hirata T, Miyasaka M. Nepmucin\/CLM-9, an Ig domain-containing sialomucin in vascular endothelial cells, promotes lymphocyte transendothelial migration <em>in vitro<\/em>.<strong><em> FEBS Lett.<\/em><\/strong> 582:3018-3024, 2008<\/li>\n<li>Furukawa Y, <strong>Umemoto E, <\/strong>Jang MH, Tohya K, Miyasaka M, Hirata T. Identification of novel isoforms of mouse L-selectin with different carboxyl-terminal tails.<strong><em> J Biol Chem.<\/em><\/strong>283:12112-12119. 2008<\/li>\n<li>Guo Z, Jang MH, Otani K, Bai Z, <strong>Umemoto E<\/strong>, Matsumoto M, Nishiyama M, Yamasaki M, Ueha S, Matsushima K, Hirata T, Miyasaka M. CD4<sup>+<\/sup>CD25<sup>+<\/sup> regulatory T cells in the small intestinal lamina propria show an effector\/memory phenotype. <strong><em>Int Immunol.<\/em><\/strong> 20:307-315, 2008<\/li>\n<li>Matsutani T, Tanaka T, Tohya K, Otani K, Jang MH, <strong>Umemoto E,<\/strong> Taniguchi K, Hayasaka H, Ueda K, Miyasaka M. Plasmacytoid dendritic cells employ multiple cell adhesion molecules sequentially to interact with high endothelial venule cells&#8211;molecular basis of their trafficking to lymph nodes. <strong><em>Int Immunol.<\/em><\/strong> 19:1031-1037, 2007<\/li>\n<li>Yotsui T, Yasuda O, Kawamoto H, Higuchi M, Chihara Y, <strong>Umemoto E<\/strong>, Tanaka T, Miyasaka M, Rakugi H, Ogihara T. Aspirin prevents adhesion of T lymphoblasts to vascular smooth muscle cells. <strong><em>FEBS Lett.<\/em><\/strong> 581:427-432, 2007<\/li>\n<li>Araki-Sasaki K, Tanaka T, Ebisuno Y, Kanda H, <strong>Umemoto E,<\/strong> Hayashi K, Miyasaka M. Dynamic expression of chemokines and the infiltration of inflammatory cells in the HSV-infected cornea and its associated tissues.<strong><em> Ocul Immunol Inflamm.<\/em><\/strong> 14:257-266, 2006<\/li>\n<li><strong>Umemoto E, <\/strong>Tanaka T, Kanda H, Jin S, Tohya K, Otani K, Matsutani T, Matsumoto M, Ebisuno Y, Jang MH, Fukuda M, Hirata T, Miyasaka M. Nepmucin, a novel HEV sialomucin, mediates L-selectin-dependent lymphocyte rolling and promotes lymphocyte adhesion under flow. <strong><em>J Exp Med.<\/em><\/strong> 203:1603-1614. 2006<\/li>\n<li>Jang MH, Sougawa N, Tanaka T, Hirata T, Hiroi T, Tohya K, Guo Z, <strong>Umemoto E,<\/strong> Ebisuno Y, Yang BG, Seoh JY, Lipp M, Kiyono H, Miyasaka M. CCR7 is critically important for migration of dendritic cells in intestinal lamina propria to mesenteric lymph nodes. <strong><em>J Immunol.<\/em><\/strong> 176:803-810, 2006<\/li>\n<li>Matsumoto M, Atarashi K, <strong>Umemoto E, <\/strong>Furukawa Y, Shigeta A, Miyasaka M, Hirata T. CD43 functions as a ligand for E-Selectin on activated T cells. <strong><em>J Immunol. <\/em><\/strong>175:8042-8050. 2005<\/li>\n<li>Kanda H, Tanaka T, Matsumoto M, <strong>Umemoto E, <\/strong>Ebisuno Y, Kinoshita M, Noda M, Kannagi R, Hirata T, Murai T, Fukuda M, Miyasaka M. Endomucin, a sialomucin expressed in high endothelial venules, supports L-selectin-mediated rolling. <strong><em>Int Immunol.<\/em><\/strong> 16:1265-1274, 2004<\/li>\n<li>Tanaka T, Ebisuno Y, Kanemitsu N, <strong>Umemoto E,<\/strong> Yang BG, Jang MH, Miyasaka M. Molecular determinants controlling homeostatic recirculation and tissue-specific trafficking of lymphocytes. <strong><em>Int Arch Allergy Immunol. <\/em><\/strong>134:120-134, 2004<\/li>\n<li>Takeuchi E, Tanaka T, <strong>Umemoto E,<\/strong> Tomita T, Shi K, Takahi K, Suzuki R, Ochi T, Miyasaka M.VLA-4-dependent and -independent pathways in cell contact-induced proinflammatory cytokine production by synovial nurse-like cells from rheumatoid arthritis patients. <strong><em>Arthritis Res. <\/em><\/strong>4:R10, 2002;<\/li>\n<li>Park CG, Takahara K, <strong>Umemoto E, <\/strong>Yashima Y, Matsubara K, Matsuda Y, Clausen BE, Inaba K, Steinman RM.Five mouse homologues of the human dendritic cell C-type lectin, DC-SIGN.<strong><em> Int Immunol.<\/em><\/strong> 13:1283-1290, 2001<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>2026\u5e74 Nakanishi K, Yukishima K,\u00a0Umemoto E. The potential of GPR31 as a target for effective oral vaccination ( [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-18","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/immunol\/wp-json\/wp\/v2\/pages\/18","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/immunol\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/immunol\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/immunol\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/immunol\/wp-json\/wp\/v2\/comments?post=18"}],"version-history":[{"count":13,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/immunol\/wp-json\/wp\/v2\/pages\/18\/revisions"}],"predecessor-version":[{"id":654,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/immunol\/wp-json\/wp\/v2\/pages\/18\/revisions\/654"}],"wp:attachment":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/immunol\/wp-json\/wp\/v2\/media?parent=18"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}