{"id":2702,"date":"2023-12-06T18:39:51","date_gmt":"2023-12-06T09:39:51","guid":{"rendered":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=2702"},"modified":"2024-08-01T09:42:30","modified_gmt":"2024-08-01T00:42:30","slug":"%e6%8a%97%e7%94%9f%e7%89%a9%e8%b3%aa%e7%94%9f%e7%94%a3%e8%8f%8c%e3%81%8c%e8%87%aa%e8%ba%ab%e3%81%ae%e7%94%9f%e7%94%a3%e3%81%99%e3%82%8b%e6%8a%97%e7%94%9f%e7%89%a9%e8%b3%aa%e3%81%a7%e6%ad%bb%e6%bb%85","status":"publish","type":"post","link":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=2702","title":{"rendered":"\u6297\u751f\u7269\u8cea\u751f\u7523\u83cc\u304c\u81ea\u8eab\u306e\u751f\u7523\u3059\u308b\u6297\u751f\u7269\u8cea\u3067\u6b7b\u6ec5\u3057\u306a\u3044\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u89e3\u660e"},"content":{"rendered":"\n<p><strong>\u6297\u751f\u7269\u8cea\u751f\u7523\u83cc\u304c\u81ea\u8eab\u306e\u751f\u7523\u3059\u308b\u6297\u751f\u7269\u8cea\u3067\u6b7b\u6ec5\u3057\u306a\u3044\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u89e3\u660e<\/strong><strong><\/strong><\/p>\n\n\n\n<p>\u3000\u672c\u5b66\u85ac\u5b66\u90e8 \u6e21\u8fba \u8ce2\u4e8c \u6559\u6388\u3001\u6a4b\u672c \u535a \u6559\u6388\u3001\u4f50\u85e4 \u9053\u5927 \u51c6\u6559\u6388\u3001\u539f \u5e78\u5927 \u51c6\u6559\u6388\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6297\u751f\u7269\u8cea\u751f\u7523\u83cc\u304c\u81ea\u8eab\u306e\u751f\u7523\u3059\u308b\u6297\u751f\u7269\u8cea\u3067\u6b7b\u6ec5\u3057\u306a\u3044\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u89e3\u660e\u3057\u307e\u3057\u305f\u3002\u672c\u6210\u679c\u306f\u3001\u5316\u5b66\u5206\u91ce\u306b\u304a\u3044\u3066\u6700\u3082\u6a29\u5a01\u306e\u3042\u308b\u56fd\u969b\u5316\u5b66\u96d1\u8a8c\u300cJournal of the American Chemical Society\u300d(Impact Factor: 16.383) 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class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"886\" height=\"477\" src=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2024\/07\/download-1.png\" alt=\"\" class=\"wp-image-2704\" srcset=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2024\/07\/download-1.png 886w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2024\/07\/download-1-300x162.png 300w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2024\/07\/download-1-768x413.png 768w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2024\/07\/download-1-465x250.png 465w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2024\/07\/download-1-695x374.png 695w\" sizes=\"auto, (max-width: 886px) 100vw, 886px\" \/><\/figure>\n\n\n\n<p>\u6297\u751f\u7269\u8cea\u8010\u6027\u30bf\u30f3\u30d1\u30af\u8cea\u304a\u3088\u3073\u30d7\u30ea\u30f3\u751f\u5408\u6210\u9175\u7d20PPAT\u306e\u6297\u751f\u7269\u8cea\u7d50\u5408\u69d8\u5f0f<\/p>\n\n\n\n<p>\u3008\u63b2\u8f09\u3055\u308c\u305f\u8ad6\u6587\u3009<\/p>\n\n\n\n<p><strong>Uncommon arrangement of self-resistance allows biosynthesis of de novo purine biosynthesis inhibitor that acts as immunosuppressor&nbsp;<\/strong><\/p>\n\n\n\n<p>Michio Sato, Sakurako Sakano, Miku Nakahara, Yui Tamura, Kodai Hara, Hiroshi Hashimoto, Yi Tang and Kenji Watanabe<\/p>\n\n\n\n<p>\u95a2\u9023\u30ea\u30f3\u30af\uff1a<a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.1c13621\">American Chemical Society<\/a><\/p>\n\n\n\n<figure class=\"wp-block-embed\"><div class=\"wp-block-embed__wrapper\">\nhttps:\/\/pubs.acs.org\/doi\/10.1021\/jacs.3c09600\n<\/div><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>\u6297\u751f\u7269\u8cea\u751f\u7523\u83cc\u304c\u81ea\u8eab\u306e\u751f\u7523\u3059\u308b\u6297\u751f\u7269\u8cea\u3067\u6b7b\u6ec5\u3057\u306a\u3044\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u89e3\u660e \u3000\u672c\u5b66\u85ac\u5b66\u90e8 \u6e21\u8fba \u8ce2\u4e8c \u6559\u6388\u3001<span class=\"more-link\"><a href=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=2702\">Continue Reading<\/a><\/span><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[39],"tags":[],"class_list":["entry","author-w3pharm","post-2702","post","type-post","status-publish","format-standard","category-39"],"_links":{"self":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2702","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2702"}],"version-history":[{"count":1,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2702\/revisions"}],"predecessor-version":[{"id":2705,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/2702\/revisions\/2705"}],"wp:attachment":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2702"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2702"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2702"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}