{"id":4034,"date":"2014-06-23T10:32:00","date_gmt":"2014-06-23T01:32:00","guid":{"rendered":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=4034"},"modified":"2024-10-10T10:57:24","modified_gmt":"2024-10-10T01:57:24","slug":"%e6%9c%ac%e5%ba%b6%e7%90%86%e4%ba%8b%e9%95%b7%e3%81%8c%e6%9d%b1%e6%b4%8b%e7%89%88%e3%83%8e%e3%83%bc%e3%83%99%e3%83%ab%e8%b3%9e%e3%80%8c%e5%94%90%e5%a5%a8%e3%80%8d%e3%81%ae%e3%83%90%e3%82%a4%e3%82%aa","status":"publish","type":"post","link":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=4034","title":{"rendered":"\u672c\u5eb6\u7406\u4e8b\u9577\u304c\u6771\u6d0b\u7248\u30ce\u30fc\u30d9\u30eb\u8cde\u300c\u5510\u5968\u300d\u306e\u30d0\u30a4\u30aa\u533b\u5b66\u90e8\u9580\u53d7\u8cde\u3057\u307e\u3057\u305f"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"alignleft size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"704\" src=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2014\/06\/20140623honjo-face.jpg\" alt=\"\" class=\"wp-image-4036\" style=\"width:311px;height:auto\" srcset=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2014\/06\/20140623honjo-face.jpg 500w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2014\/06\/20140623honjo-face-213x300.jpg 213w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2014\/06\/20140623honjo-face-391x550.jpg 391w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2014\/06\/20140623honjo-face-355x500.jpg 355w\" sizes=\"auto, (max-width: 500px) 100vw, 500px\" \/><\/figure>\n<\/div>\n\n\n<p>\u53f0\u6e7e\u306e\u8d77\u696d\u5bb6\u96c6\u56e3\u306b\u3088\u308a\u8a2d\u7acb\u3055\u308c\u305f\u300c\u6771\u6d0b\u7248\u30ce\u30fc\u30d9\u30eb\u8cde\u300d\u3068\u3055\u308c\u308b\u300c\u5510\u5968\uff082014 Tang Prize\uff09\u300d\u306e\u30d0\u30a4\u30aa\u533b\u5b66\u90e8\u9580\u306e\u8a18\u5ff5\u3059\u3079\u304d\u7b2c1\u56de\u53d7\u8cde\u8005\u3068\u3057\u3066\u3001\u672c\u5b66\u7406\u4e8b\u9577\u3000\u672c\u5eb6\u4f51\u535a\u58eb\u304c\u9078\u3070\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3000\u30a2\u30e1\u30ea\u30ab\u3000\u30c6\u30ad\u30b5\u30b9\u5927\u5b66\u7814\u7a76\u8005\u3068\u306e\u5171\u540c\u53d7\u8cde\u3068\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u2028\u3000\u53d7\u8cde\u984c\u76ee<\/p>\n\n\n\n<p>\u3000\u300cThe discoveries of CTLA-4 and PD-1 as immune inhibitory moleculesthat led to their applications in cancer immunotherapy\u300d\u2028\u2028<\/p>\n\n\n\n<p>\u514d\u75ab\u6a5f\u69cb\u306e\u8981\u3067\u3042\u308b\u300cT\u7d30\u80de\u300d\u306e\u514d\u75ab\u5fdc\u7b54\u8abf\u7bc0\u306b\u95a2\u308f\u308b\u30bf\u30f3\u30d1\u30af\u8ceaCTLA-4 \u3001PD-1\u306f\u3001\u514d\u75ab\u7cfb\u306e\u904e\u5270\u306a\u50cd\u304d\u3092\u6291\u3048\u308b\u91cd\u8981\u306a\u5f79\u5272\u3092\u62c5\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u6a5f\u69cb\u304c\u89e3\u660e\u3055\u308c\u305f\u3053\u3068\u3067\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\uff08\u81ea\u5206\u306e\u514d\u75ab\u7d30\u80de\u304c\u81ea\u5206\u306e\u6b63\u5e38\u7d30\u80de\u3092\u3082\u653b\u6483\u3057\u3066\u3057\u307e\u3046\u3053\u3068\u3067\u5f15\u304d\u8d77\u3053\u3055\u308c\u308b\u75c5\u6c17\uff09\u306e\u6839\u672c\u7684\u306a\u6291\u5236\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u307e\u305f\u3001\u7279\u5b9a\u306e\u304c\u3093\u7d30\u80de\u304cPD-1\u306b\u7d50\u5408\u3057\u514d\u75ab\u304b\u3089\u9003\u308c\u308b\u6a5f\u69cb\u304c\u660e\u3089\u304b\u3068\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>PD-1\u306e\u6a5f\u80fd\u3092\u6291\u3048\u308b\u3053\u3068\u3067\u3001\u60aa\u6027\u816b\u760d\u306b\u5bfe\u3059\u308b\u514d\u75ab\u53cd\u5fdc\u3092\u5897\u5f37\u3067\u304d\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u308a\u3001\u307e\u3063\u305f\u304f\u3042\u305f\u3089\u3057\u3044\u81e8\u5e8a\u85ac\u3068\u3057\u3066\u305d\u306e\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u7814\u7a76\u5185\u5bb9\u7d39\u4ecb\u3000\uff082013\u53f0\u65e5\u79d1\u5b66\u6280\u8853\u30d5\u30a9\u30fc\u30e9\u30e0 \u30c8\u30e9\u30f3\u30b9\u30ec\u30fc\u30b7\u30e7\u30ca\u30eb\u533b\u7642\u3068\u30d0\u30a4\u30aa\u7523\u696d\u306e\u767a\u5c55\uff09\u3000<\/p>\n\n\n\n<p><a href=\"http:\/\/www.tnst.org.tw\/ezcatfiles\/cust\/img\/img\/20130923_jp11.pdf\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/www.tnst.org.tw\/ezcatfiles\/cust\/img\/img\/20130923_jp11.pdf<\/a><\/p>\n\n\n\n<p>\u7523\u7d93\u65b0\u805e\u3000\u8a18\u4e8b\uff082014.6.19\uff09<\/p>\n\n\n\n<p><a href=\"http:\/\/sankei.jp.msn.com\/world\/news\/140619\/chn14061913350007-n1.htm\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/sankei.jp.msn.com\/world\/news\/140619\/chn14061913350007-n1.htm<\/a><\/p>\n\n\n\n<p>\u65e5\u7d4c\u30e1\u30c7\u30a3\u30ab\u30eb\uff08\u764cExperts\u30cb\u30e5\u30fc\u30b9\u3088\u308a\uff09<\/p>\n\n\n\n<p><a href=\"http:\/\/medical.nikkeibp.co.jp\/leaf\/all\/search\/cancer\/news\/201303\/529345.html\" target=\"_blank\" rel=\"noreferrer noopener\">http:\/\/medical.nikkeibp.co.jp\/leaf\/all\/search\/cancer\/news\/201303\/529345.html<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u53f0\u6e7e\u306e\u8d77\u696d\u5bb6\u96c6\u56e3\u306b\u3088\u308a\u8a2d\u7acb\u3055\u308c\u305f\u300c\u6771\u6d0b\u7248\u30ce\u30fc\u30d9\u30eb\u8cde\u300d\u3068\u3055\u308c\u308b\u300c\u5510\u5968\uff082014 Tang Prize\uff09<span class=\"more-link\"><a href=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=4034\">Continue Reading<\/a><\/span><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[38],"tags":[],"class_list":["entry","author-w3pharm","post-4034","post","type-post","status-publish","format-standard","category-38"],"_links":{"self":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/4034","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4034"}],"version-history":[{"count":6,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/4034\/revisions"}],"predecessor-version":[{"id":4049,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/4034\/revisions\/4049"}],"wp:attachment":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4034"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4034"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4034"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}