{"id":5023,"date":"2017-01-18T11:51:00","date_gmt":"2017-01-18T02:51:00","guid":{"rendered":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=5023"},"modified":"2024-12-23T11:52:55","modified_gmt":"2024-12-23T02:52:55","slug":"%e8%96%ac%e7%89%a9%e5%8b%95%e6%85%8b%e5%ad%a6%e5%88%86%e9%87%8e%e3%81%ae%e8%ab%96%e6%96%87%e3%81%8c%e5%ad%a6%e8%a1%93%e9%9b%91%e8%aa%8c%e3%81%ae%e8%a1%a8%e7%b4%99%e3%82%92%e9%a3%be%e3%82%8b","status":"publish","type":"post","link":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=5023","title":{"rendered":"\u85ac\u7269\u52d5\u614b\u5b66\u5206\u91ce\u306e\u8ad6\u6587\u304c\u5b66\u8853\u96d1\u8a8c\u306e\u8868\u7d19\u3092\u98fe\u308b"},"content":{"rendered":"\n

\u85ac\u5b66\u90e8 \u85ac\u7269\u52d5\u614b\u5b66\u5206\u91ce (\u5c3e\u4e0a\u8aa0\u826f \u6559\u6388\uff0c\u4e16\u6238\u5b5d\u6a39 \u52a9\u6559\uff0c\u4f50\u85e4\u79c0\u884c \u52a9\u6559) \u306e\u8ad6\u6587\u304c\uff0c\u76ae\u819a\u79d1\u9818\u57df\u306e\u5c02\u9580\u8a8c\u3067\u3042\u308b\u300cJournal of Dermatological Science\u300d(Impact Factor : 3.739\uff0c2016 \u5e74) 2017 \u5e74 85\u5dfb 1 \u53f7 (2017 \u5e74 1 \u6708\u767a\u884c) \u306e\u8868\u7d19\u306b\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\uff0e<\/p>\n\n\n\n

\u5275\u85ac\u304a\u3088\u3073\u5316\u7ca7\u54c1\u958b\u767a\u306b\u304a\u3044\u3066\uff0c\u5149\u5b89\u5168\u6027\u8a55\u4fa1\u306b\u95a2\u3059\u308b\u56fd\u969b\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3 (ICH S10 guidance \u304a\u3088\u3073 PCPC guideline) \u304c 2014 \u5e74\u306b\u65bd\u884c\u3055\u308c\u308b\u306a\u3069\u533b\u85ac\u54c1\u30fb\u5316\u7ca7\u54c1\u306b\u3088\u308b\u5149\u6bd2\u6027 (\u5149\u7dda\u904e\u654f\u75c7) \u306b\u6ce8\u76ee\u304c\u96c6\u307e\u3063\u3066\u3044\u307e\u3059\uff0e\u672c\u5b66\u85ac\u5b66\u90e8\u85ac\u7269\u52d5\u614b\u5b66\u5206\u91ce\u3067\u306f\u5149\u5316\u5b66\u7684\u8a55\u4fa1\u65b9\u6cd5\u3067\u3042\u308b ROS assay \u3092\u306f\u3058\u3081\u3068\u3057\u3066\uff0c\u5149\u6bd2\u6027\u306e\u767a\u75c7\u6a5f\u5e8f\u306b\u57fa\u3065\u304f\u5149\u5b89\u5168\u6027\u8a55\u4fa1\u624b\u6cd5\u306e\u958b\u767a\u306b\u53d6\u308a\u7d44\u3093\u3067\u304a\u308a\uff0c\u958b\u767a\u3057\u305f\u8a55\u4fa1\u7cfb\u306f\u65e2\u306b\u56fd\u969b\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3\u306b\u63a1\u7528\u3055\u308c\uff0c\u4e16\u754c\u4e2d\u306e\u88fd\u85ac\u4f01\u696d\u3084\u98df\u54c1\u30fb\u5316\u7ca7\u54c1\u30e1\u30fc\u30ab\u30fc\u3067\u6d3b\u7528\u3055\u308c\u3066\u3044\u307e\u3059\uff0e\u672c\u8ad6\u6587\u3067\u306f\u5149\u6bd2\u6027\u306e\u306a\u304b\u3067\u5149\u30a2\u30ec\u30eb\u30ae\u30fc\u53cd\u5fdc\u3068\u547c\u3070\u308c\u308b\u6709\u5bb3\u4e8b\u8c61\u306e\u767a\u75c7\u6a5f\u5e8f\u3068\uff0c\u305d\u306e\u539f\u56e0\u3068\u306a\u308b\u5316\u5b66\u7269\u8cea\u304a\u3088\u3073\u5149\u30a2\u30ec\u30eb\u30ae\u30fc\u30ea\u30b9\u30af\u306e\u8a55\u4fa1\u624b\u6cd5\u306b\u3064\u3044\u3066\u6700\u65b0\u306e\u77e5\u898b\u3092\u7d39\u4ecb\u3057\u3066\u3044\u307e\u3059\uff0e<\/p>\n\n\n\n

\u672c\u8ad6\u6587\u306f\u6d5c\u677e\u533b\u79d1\u5927\u5b66\uff0c\u682a\u5f0f\u4f1a\u793e\u8cc7\u751f\u5802\uff0cResearch Institute for Fragrance Materials\uff0cDABMEB Consultancy \u3068\u306e\u5171\u540c\u7814\u7a76\u6210\u679c\u3067\u3059\uff0e<\/p>\n\n\n\n

\"\"<\/figure>\n\n\n\n

\u63b2\u8f09\u3055\u308c\u305f\u8ad6\u6587<\/h3>\n\n\n\n

Satomi Onoue, Yoshiki Seto, Hideyuki Sato, Hayato Nishida, Morihiko Hirota, Takao Ashikaga, Anne Marie Api, David Basketter, Yoshiki Tokura, Chemical photoallergy: photobiochemical mechanisms, classification, and risk assessments, Journal of Dermatological Science, 85(1): 4\u201311 (2017)<\/p>\n\n\n\n

\u95a2\u9023URL<\/h3>\n\n\n\n

Journal of Dermatological Science: http:\/\/www.jdsjournal.com\/<\/a><\/p>\n\n\n\n

\u85ac\u7269\u52d5\u614b\u5b66\u5206\u91ce HP\uff1a http:\/\/w3pharm.u-shizuoka-ken.ac.jp\/yakuzai\/<\/a><\/p>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

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