{"id":5105,"date":"2016-08-26T10:21:00","date_gmt":"2016-08-26T01:21:00","guid":{"rendered":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=5105"},"modified":"2025-01-10T10:23:31","modified_gmt":"2025-01-10T01:23:31","slug":"%e6%97%a5%e6%9c%ac%e9%85%92%e9%86%b8%e9%80%a0%e3%81%ae%e4%b8%bb%e5%bd%b9%e3%82%b3%e3%82%a6%e3%82%b8%e8%8f%8c%e3%81%ae%e6%8c%81%e3%81%a4%e5%a4%9a%e6%a9%9f%e8%83%bd%e5%9e%8b%e3%83%95%e3%83%a9","status":"publish","type":"post","link":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=5105","title":{"rendered":"\u65e5\u672c\u9152\u91b8\u9020\u306e\u4e3b\u5f79\u2022\u30b3\u30a6\u30b8\u83cc\u306e\u6301\u3064\u591a\u6a5f\u80fd\u578b\u30d5\u30e9\u30d3\u30f3\u9175\u7d20\u306e\u767a\u898b"},"content":{"rendered":"\n<p><strong>\u65e5\u672c\u9152\u91b8\u9020\u306e\u4e3b\u5f79\u2022\u30b3\u30a6\u30b8\u83cc\u306e\u6301\u3064\u591a\u6a5f\u80fd\u578b\u30d5\u30e9\u30d3\u30f3\u9175\u7d20\u306e\u767a\u898b\u301c\u4e0d\u6d3b\u6027\u578b\u98fd\u548c\u70ad\u5316\u6c34\u7d20\u3078\u306e\u591a\u91cd\u5869\u7d20\u5316\u3068\u82b3\u9999\u65cf\u6027\u6c34\u9178\u57fa\u306e\u591a\u91cd\u30e1\u30c1\u30eb\u5316\u3092\u89e6\u5a92\u301c<\/strong><\/p>\n\n\n\n<p>\u672c\u5b66\u85ac\u5b66\u90e8 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oryzae<\/em>\uff08\u30a2\u30b9\u30da\u30eb\u30ae\u30eb\u30b9\u30fb\u30aa\u30ea\u30bc\u30fc\uff09\u306e\u751f\u7523\u3059\u308b\u6297\u751f\u7269\u8cea\u300c\u30c0\u30a4\u30a2\u30dd\u30fc\u30c1\u30f3\u300d\u306e\u751f\u5408\u6210\u7d4c\u8def\u306b\u304a\u3044\u3066\u3001\u5316\u5b66\u69cb\u9020\u306b\u542b\u307e\u308c\u308b\u30b8\u30af\u30ed\u30ed\u30e1\u30c1\u30eb\u69cb\u9020\u304c\u30d5\u30e9\u30d3\u30f3\u4f9d\u5b58\u578b\u30cf\u30ed\u30b2\u30f3\u5316\u9175\u7d20AoiQ\u306b\u3088\u308a\u5f62\u6210\u3055\u308c\u308b\u3053\u3068\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u30e1\u30c1\u30eb\u57fa\u306a\u3069\u306e\u8102\u80aa\u65cf\u70ad\u5316\u6c34\u7d20\u306e\u70ad\u7d20\u2014\u6c34\u7d20\u7d50\u5408\u306f\u5316\u5b66\u7684\u306b\u4e0d\u6d3b\u6027\u3067\u3042\u308a\u3001\u91d1\u5c5e\u89e6\u5a92\u3084\u6d3b\u6027\u4e2d\u5fc3\u306b\u9244\u3092\u542b\u3080\u751f\u4f53\u89e6\u5a92\u3092\u7528\u3044\u3066\u3053\u306e\u7d50\u5408\u3092\u958b\u88c2\u3055\u305b\u308b\u7814\u7a76\u304c\u4e16\u754c\u4e2d\u3067\u76db\u3093\u306b\u884c\u308f\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u4eca\u56de\u767a\u898b\u3057\u305f\u30cf\u30ed\u30b2\u30f3\u5316\u9175\u7d20AoiQ\u306f\u6d3b\u6027\u4e2d\u5fc3\u306b\u9244\u306a\u3069\u306e\u91d1\u5c5e\u3092\u6301\u305f\u305a\u3001\u4ee3\u308f\u308a\u306b\u30d5\u30e9\u30d3\u30f3\u88dc\u9175\u7d20\u3092\u6709\u3059\u308b\u4e16\u754c\u3067\u521d\u3081\u3066\u306e\u4f8b\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u307e\u305fAoiQ\u306fC\u672b\u7aef\u9818\u57df\u306e\u30e1\u30c1\u30eb\u57fa\u8ee2\u79fb\u6d3b\u6027\u306b\u3088\u308a\u3001\u30c0\u30a4\u30a2\u30dd\u30fc\u30c1\u30f3\u306e\u82b3\u9999\u65cf\u6c34\u9178\u57fa\u306e\u30e1\u30c1\u30eb\u5316\u3092\u89e6\u5a92\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u306b\u306a\u308a\u307e\u3057\u305f\u3002\u4eca\u56de\u3001\u767a\u898b\u3057\u305f\u9175\u7d20\u3092\u4eba\u5de5\u7684\u306b\u6539\u5909\u3059\u308b\u3053\u3068\u3067\u5869\u7d20\u539f\u5b50\u3092\u81ea\u5728\u306b\u5c0e\u5165\u3067\u304d\u308b\u89e6\u5a92\u306e\u5275\u88fd\u304c\u53ef\u80fd\u306b\u306a\u308b\u3068\u671f\u5f85\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u672c\u7814\u7a76\u6210\u679c\u306f\u3001\u672c\u5b66\u85ac\u5b66\u90e8 \u751f\u85ac\u5b66\u5206\u91ce&nbsp;(\u6e21\u8fba \u8ce2\u4e8c \u6559\u6388\u3001\u6052\u677e \u96c4\u592a \u52a9\u6559\u3001\u85ac\u5b66\u79d16\u5e74\u751f \u4f50\u3005 \u4f91\u5bff\u9999)&nbsp;\u3068\u72ec\u56fdLeibniz Institute for Natural Product Research and Infection Biology \u2013 Hans Kn\u00f6ll Institute (HKI)\u3000Christian Hertweck&nbsp;\u6559\u6388\u3089\u306b\u3088\u308bJSPS\u982d\u8133\u5faa\u74b0\u5171\u540c\u7814\u7a76\u6210\u679c\u3067\u3042\u308a\u3001\u5316\u5b66\u5206\u91ce\u306b\u304a\u3044\u3066\u6a29\u5a01\u306e\u3042\u308b\u56fd\u969b\u5316\u5b66\u96d1\u8a8c\u300cAngewandte Chemie International Edition\u300d(5-Year Impact Factor: 12.06)&nbsp;\u96fb\u5b50\u7248\u306b2016\u5e748\u670825\u65e5\u4ed8\u3051\u3067\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p>\u3008\u63b2\u8f09\u3055\u308c\u305f\u8ad6\u6587\u3009<\/p>\n\n\n\n<p><strong>Regioselective Dichlorination of a Non-Activated Aliphatic Carbon Atom and Phenolic Bismethylation by a Multifunctional Fungal Flavoenzyme<\/strong><\/p>\n\n\n\n<p>Pranatchareeya Chankhamjon, Yuta Tsunematsu, Mie Ishida-Ito, Yuzuka Sasa, Florian Meyer, \u2028Daniela Boettger-Schmidt, Barbara Urbansky, Klaus-Dieter Menzel, Kirstin Scherlach, \u2028Kenji Watanabe, Christian Hertweck*&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"570\" height=\"347\" src=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2025\/01\/image-4.png\" alt=\"\" class=\"wp-image-5106\" srcset=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2025\/01\/image-4.png 570w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2025\/01\/image-4-300x183.png 300w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2025\/01\/image-4-465x283.png 465w\" sizes=\"auto, (max-width: 570px) 100vw, 570px\" \/><\/figure>\n\n\n\n<p>\u95a2\u9023\u30ea\u30f3\u30af\uff1aWiley Online Library<\/p>\n\n\n\n<p><a href=\"http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201604516\/full\">http:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201604516\/full&nbsp; &nbsp;&nbsp;<\/a><\/p>\n\n\n\n<p>\u9759\u5ca1\u770c\u7acb\u5927\u5b66 \u85ac\u5b66\u90e8 \u751f\u85ac\u5b66\u7814\u7a76\u5ba4<\/p>\n\n\n\n<p><a href=\"http:\/\/sweb.u-shizuoka-ken.ac.jp\/~kenji55-lab\/\">http:\/\/sweb.u-shizuoka-ken.ac.jp\/~kenji55-lab\/<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u65e5\u672c\u9152\u91b8\u9020\u306e\u4e3b\u5f79\u2022\u30b3\u30a6\u30b8\u83cc\u306e\u6301\u3064\u591a\u6a5f\u80fd\u578b\u30d5\u30e9\u30d3\u30f3\u9175\u7d20\u306e\u767a\u898b\u301c\u4e0d\u6d3b\u6027\u578b\u98fd\u548c\u70ad\u5316\u6c34\u7d20\u3078\u306e\u591a\u91cd\u5869\u7d20\u5316\u3068\u82b3\u9999<span class=\"more-link\"><a href=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=5105\">Continue Reading<\/a><\/span><\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[39],"tags":[],"class_list":["entry","author-gp2188","post-5105","post","type-post","status-publish","format-standard","category-39"],"_links":{"self":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/5105","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5105"}],"version-history":[{"count":1,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/5105\/revisions"}],"predecessor-version":[{"id":5107,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/5105\/revisions\/5107"}],"wp:attachment":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5105"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}