{"id":5235,"date":"2025-03-21T19:20:08","date_gmt":"2025-03-21T10:20:08","guid":{"rendered":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=5235"},"modified":"2025-03-21T19:20:08","modified_gmt":"2025-03-21T10:20:08","slug":"%e5%a4%a9%e7%84%b6%e7%89%a9%e3%81%ab%e9%80%b2%e5%8c%96%e3%81%ae%e5%bd%a2%e8%b7%a1%e3%82%92%e7%99%ba%e8%a6%8b%e3%80%9c%e5%a4%a9%e7%84%b6%e7%89%a9%e9%80%b2%e5%8c%96%e8%ab%96%e3%80%9c","status":"publish","type":"post","link":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=5235","title":{"rendered":"\u5929\u7136\u7269\u306b\u9032\u5316\u306e\u5f62\u8de1\u3092\u767a\u898b\u301c\u5929\u7136\u7269\u9032\u5316\u8ad6\u301c"},"content":{"rendered":"\n<p class=\"has-black-color has-text-color has-link-color wp-elements-b0a1eff51bcf376202d5104a4ab1bf75\" style=\"padding-top:var(--wp--preset--spacing--30);padding-bottom:var(--wp--preset--spacing--30);font-size:20px;font-style:normal;font-weight:600\">\u672c\u5b66\u85ac\u5b66\u90e8 \u6e21\u8fba \u8ce2\u4e8c \u6559\u6388\u3001\u5cb8\u672c \u771f\u6cbb \u8b1b\u5e2b\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6297\u751f\u7269\u8cea\u306e\u3088\u3046\u306a\u5929\u7136\u6709\u6a5f\u5316\u5408\u7269\u306b\u9032\u5316\u306e\u5f62\u8de1\u3092\u898b\u51fa\u3057\u5831\u544a\u3057\u307e\u3057\u305f\u3002\u672c\u6210\u679c\u306f\u3001\u5316\u5b66\u5206\u91ce\u306b\u304a\u3044\u3066\u6700\u3082\u6a29\u5a01\u306e\u3042\u308b\u56fd\u969b\u5316\u5b66\u96d1\u8a8c\u300cJournal of the American Chemical Society\u300d(Impact Factor: 14.5) \u96fb\u5b50\u7248\u306b2025\u5e743\u670818\u65e5\u4ed8\u3051\u3067\u63b2\u8f09\u3055\u308c\u307e\u3057\u305f\u3002<\/p>\n\n\n\n<p class=\"has-text-align-left has-text-color has-link-color wp-elements-61523dcb95d0bd3af60dc10eb5449467\" style=\"color:#000000c7;padding-right:0;padding-left:0;font-size:18px\">\u5fae\u751f\u7269\u3084\u690d\u7269\u306b\u3088\u3063\u3066\u751f\u7523\u3055\u308c\u3066\u3044\u308b\u5929\u7136\u7269\u306e\u591a\u304f\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u3084\u6838\u9178\u7b49\u306e\u751f\u4f53\u9ad8\u5206\u5b50\u3092\u6a19\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u5929\u7136\u7269\u306f\u6a19\u7684\u3068\u306a\u308b\u751f\u4f53\u9ad8\u5206\u5b50\u306b\u5408\u308f\u305b\u3066\u7acb\u4f53\u9078\u629e\u7684\u306b\u751f\u5408\u6210\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u304c\u4e00\u822c\u7684\u3067\u3042\u308a\u3001\u975e\u9175\u7d20\u7684\u306a\u53cd\u5fdc\u306b\u3088\u308b\u751f\u6210\u7269\u3084\u751f\u5408\u6210\u4e2d\u9593\u4f53\u3092\u9664\u3051\u3070\u5929\u7136\u304b\u3089\u7acb\u4f53\u7570\u6027\u4f53\u304c\u5f97\u3089\u308c\u308b\u30b1\u30fc\u30b9\u306f\u5c11\u306a\u3044\u3002\u7279\u306b\u93e1\u50cf\u4f53\u306e\u95a2\u4fc2\u306b\u3042\u308b\u30a8\u30ca\u30f3\u30c1\u30aa\u30de\u30fc\u306f\u5316\u5b66\u69cb\u9020\u89e3\u6790\u306b\u6c4e\u7528\u3055\u308c\u308bLC\u2013MS\u3084NMR\u3067\u5224\u5225\u3067\u304d\u306a\u3044\u3053\u3068\u3082\u3042\u308a\u3001\u5929\u7136\u304b\u3089\u306e\u5831\u544a\u4f8b\u306f\u3054\u304f\u7a00\u3067\u3042\u308a\u307e\u3059\u3002\u4eca\u56de\u3001\u6211\u3005\u306f\u30cb\u30c8\u30ea\u30eb\u57fa\u542b\u6709\u5929\u7136\u7269\u3067\u3042\u308bauranthine\u306e\u751f\u5408\u6210\u7814\u7a76\u306e\u904e\u7a0b\u3067\u3001<em>Aspergillus lentulus<\/em>\u306e\u4e2d\u306b (\u2212)-auranthine (<strong>1<\/strong>) \u3092\u751f\u7523\u3059\u308b\u83cc\u682a\u3068\u3053\u308c\u307e\u3067\u306b\u672a\u767a\u898b\u3067\u3042\u3063\u305f (+)-auranthine (<strong>2<\/strong>) \u3092\u751f\u7523\u3059\u308b\u83cc\u682a\u304c\u305d\u308c\u305e\u308c\u5b58\u5728\u3059\u308b\u3053\u3068\u3092\u521d\u3081\u3066\u898b\u51fa\u3057\u3001\u305d\u306e\u751f\u80b2\u7bc4\u56f2\u304c\u5927\u9678\u306b\u4f9d\u5b58\u3059\u308b\u3053\u3068\u3082\u793a\u3055\u308c\u3001<strong>1<\/strong>\u304a\u3088\u3073<strong>2<\/strong>\u306e\u7acb\u4f53\u5316\u5b66\u306e\u9055\u3044\u306f\u751f\u7269\u6d3b\u6027\u304c\u6c42\u3081\u305f\u5206\u5b50\u9032\u5316\u3067\u3042\u308b\u3068\u985e\u63a8\u3057\u3001\u30cb\u30c8\u30ea\u30eb\u57fa\u306e\u751f\u5408\u6210\u3092\u542b\u3081\u305f\u30a8\u30ca\u30f3\u30c1\u30aa\u30de\u30fc\u306e\u9032\u5316\u751f\u5408\u6210\u6a5f\u69cb\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"505\" height=\"323\" src=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2025\/03\/image.png\" alt=\"\" class=\"wp-image-5236\" srcset=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2025\/03\/image.png 505w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2025\/03\/image-300x192.png 300w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/wp-content\/uploads\/2025\/03\/image-465x297.png 465w\" sizes=\"auto, (max-width: 505px) 100vw, 505px\" \/><\/figure>\n<\/div>\n\n\n<p><\/p>\n\n\n\n<p>\u3008\u63b2\u8f09\u3055\u308c\u305f\u8ad6\u6587\u3009<\/p>\n\n\n\n<p><strong>Enantioselective biosynthesis of (+)- and (\u2013)-auranthines<\/strong><\/p>\n\n\n\n<p>Shinji Kishimoto, Tsubasa Tamura, Takumi Okamoto and Kenji Watanabe<\/p>\n\n\n\n<p>\u95a2\u9023\u30ea\u30f3\u30af\uff1aAmerican Chemical Society <a href=\"https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.5c00470\">https:\/\/pubs.acs.org\/doi\/10.1021\/jacs.5c00470<\/a><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u672c\u5b66\u85ac\u5b66\u90e8 \u6e21\u8fba \u8ce2\u4e8c \u6559\u6388\u3001\u5cb8\u672c \u771f\u6cbb \u8b1b\u5e2b\u306e\u30b0\u30eb\u30fc\u30d7\u306f\u3001\u6297\u751f\u7269\u8cea\u306e\u3088\u3046\u306a\u5929\u7136\u6709\u6a5f\u5316\u5408\u7269\u306b\u9032\u5316\u306e\u5f62<span class=\"more-link\"><a href=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/?p=5235\">Continue Reading<\/a><\/span><\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[39],"tags":[],"class_list":["entry","author-hpmember","post-5235","post","type-post","status-publish","format-standard","category-39"],"_links":{"self":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/5235","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5235"}],"version-history":[{"count":13,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/5235\/revisions"}],"predecessor-version":[{"id":5249,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/5235\/revisions\/5249"}],"wp:attachment":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5235"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5235"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5235"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}