Graduate students from other universities and departments are welcome.

Hamashima Synthetic Organic Chemistry Laboratory

2013/10/31 Lawn Park

Synthetic organic chemistry plays an important role not only in drug discovery but also in material sciences.  Since pharmaceutical drugs are essential for the welfare of humankind, their chemical synthesis should be environmentally friendly and not produce any toxic wastes.  We believe that we can find some hints in nature for the improvement of our synthetic technology.  Through appreciation and reorganization of nature’s principles, we aim at developing molecular catalysts to achieve efficient chemical syntheses.  Another important feature of organic chemistry is creating valuable functional molecules by designing novel molecular frameworks.  For the development of biologically-relevant molecules, we have a great interest in utilizing as key probes particular elements and atomic groups that are not found in the human body.

As a part of our study of synthetic methodologies, we have been engaged in asymmetric catalysis using transition metal complexes, and have achieved efficient total syntheses of a variety of bioactive compounds.  We have also developed various efficient methods of incorporating fluorine atoms that are useful for designing new functional molecules.  With these research projects as our main focus, we are currently investigating the following areas in our laboratory:

1.      Development of novel catalytic reactions and asymmetric synthesis

2.      Synthetic studies of biologically interesting natural and unnatural compounds

3.      Investigations into allenes and their synthetic applications

4.      Studies of bio-organometallic chemistry for controlling biological events

News & Topics

2014.02.10. English HP is opened.