{"id":920,"date":"2021-04-27T18:49:38","date_gmt":"2021-04-27T09:49:38","guid":{"rendered":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco_wp\/?page_id=920"},"modified":"2024-11-21T16:00:08","modified_gmt":"2024-11-21T07:00:08","slug":"%e7%a0%94%e7%a9%b6%e5%86%85%e5%ae%b9-2","status":"publish","type":"page","link":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/?page_id=920","title":{"rendered":"\u7814\u7a76\u5185\u5bb9"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"920\" class=\"elementor elementor-920\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-c0bc57e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c0bc57e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-75111d3\" data-id=\"75111d3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0bd3b37 elementor-widget elementor-widget-text-editor\" data-id=\"0bd3b37\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-family: arial, helvetica, sans-serif; color: #000000;\">\u5f53\u8b1b\u5ea7\u3067\u306f\u3001\u4e3b\u306b\u7cd6\u5c3f\u75c5\u95a2\u9023\u75be\u60a3\u306e\u75c5\u56e0\u89e3\u660e\u3084\u6cbb\u7642\u85ac\u958b\u767a\u3092\u3081\u3056\u3057\u305f\u57fa\u790e\u7814\u7a76\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p><p><span style=\"font-family: arial, helvetica, sans-serif; color: #000000;\">\u8840\u7cd6\u8abf\u7bc0\u306b\u304a\u3044\u3066\u4e2d\u5fc3\u7684\u306a\u5f79\u5272\u3092\u62c5\u3063\u3066\u3044\u308b\u81b5\u5185\u5206\u6ccc\u7d30\u80de\u3001\u53ca\u3073\u8102\u80aa\u809d\u306a\u3069\u306b\u304a\u3051\u308b\u809d\u7dda\u7dad\u5316\u306e\u8cac\u4efb\u7d30\u80de\u3067\u3042\u308b\u809d\u661f\u7d30\u80de\u3092\u4e3b\u306a\u7814\u7a76\u5bfe\u8c61\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p><p><span style=\"font-family: arial, helvetica, sans-serif; color: #000000;\">\u85ac\u7406\u5b66\u7684\u89e3\u6790\u306f\u3082\u3068\u3088\u308a\u3001\u96fb\u6c17\u751f\u7406\u5b66\u3001\u751f\u5316\u5b66\u3001\u5206\u5b50\u751f\u7269\u5b66\u3001\u907a\u4f1d\u5b50\u5de5\u5b66\u7684\u89e3\u6790\u3092\u99c6\u4f7f\u3057\u3066\u3001\u201c\u5206\u5b50\u30ec\u30d9\u30eb\u304b\u3089\u500b\u4f53\u30ec\u30d9\u30eb\u307e\u3067\u201d\u3092\u30e2\u30c3\u30c8\u30fc\u306b\u7814\u7a76\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u3001\u7d30\u80de\u5185\u5206\u5b50\u52d5\u614b\u306e\u30ea\u30a2\u30eb\u30bf\u30a4\u30e0\u6e2c\u5b9a\u306a\u3069\u306e\u751f\u7d30\u80de\u3067\u306e\u89e3\u6790\u3092\u8ef8\u3068\u3057\u3066\u3001\u30db\u30eb\u30e2\u30f3\u5206\u6ccc\u3084\u5f62\u8cea\u5909\u5316\u3001\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u306a\u3069\u306b\u5bfe\u3059\u308b\u4e00\u9178\u5316\u7a92\u7d20\u3084\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9\u985e\u306a\u3069\u306e\u52b9\u679c\u3084\u7cd6\u6bd2\u6027\u3084\u8102\u80aa\u6bd2\u6027\u306a\u3069\u306b\u3088\u308b\u5f71\u97ff\u3092\u3001\u7d30\u80de\u5185\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u306e\u89e3\u660e\u306b\u91cd\u70b9\u3092\u7f6e\u3044\u3066\u7814\u7a76\u3092\u5c55\u958b\u3057\u3066\u3044\u307e\u3059\u3002\u307e\u305f\u3001\u5e45\u5e83\u3044\u5929\u7136\u7269\u7d20\u6750\u3092\u30bf\u30fc\u30b2\u30c3\u30c8\u3068\u3057\u3066\u3001\u30e6\u30cb\u30fc\u30af\u306a\u85ac\u7406\u6d3b\u6027\u3092\u6301\u3064\u65b0\u898f\u751f\u7406\u6d3b\u6027\u7269\u8cea\u306e\u63a2\u7d22\u3082\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-016ac5e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"016ac5e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9db5929\" data-id=\"9db5929\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5e38278 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"5e38278\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-cb2fd6f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"cb2fd6f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-5a8db59\" data-id=\"5a8db59\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9ad0641 elementor-widget elementor-widget-heading\" data-id=\"9ad0641\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-medium\"><a href=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco_wp\/?page_id=481\">1.\u3000\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u5236\u5fa1\u6a5f\u69cb\u306e\u89e3\u6790<\/a><\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-53bcadc0 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"53bcadc0\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-66896e7f\" data-id=\"66896e7f\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3954e69 elementor-widget elementor-widget-text-editor\" data-id=\"3954e69\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #000000; font-family: arial, helvetica, sans-serif;\">\u8fd1\u5e74\u306e\u300c\u79d1\u5b66\u6280\u8853\u91cd\u8981\u65bd\u7b56\u30a2\u30af\u30b7\u30e7\u30f3\u30d7\u30e9\u30f3\u300d\u306e\u91cd\u70b9\u7684\u53d6\u308a\u7d44\u307f\u306b\u63b2\u3052\u3089\u308c\u3066\u3044\u308b\u3088\u3046\u306b\u3001\u5897\u3048\u7d9a\u3051\u308b\u7cd6\u5c3f\u75c5\u306b\u5bfe\u3059\u308b\u65b0\u3057\u3044\u6cbb\u7642\u3092\u958b\u767a\u3059\u308b\u3053\u3068\u306f\u3001\u7126\u7709\u306e\u8ab2\u984c\u3067\u3059\u3002\u6211\u304c\u56fd\u306e\u7cd6\u5c3f\u75c5\u306e\u5927\u534a\u3092\u5360\u3081\u308b\uff12\u578b\u7cd6\u5c3f\u75c5\u306e\u539f\u56e0\u3068\u3057\u3066\u306f\u3001\u81b5B\u7d30\u80de\u304b\u3089\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u969c\u5bb3\u306e\u5360\u3081\u308b\u5272\u5408\u304c\u5927\u304d\u3044\u3053\u3068\u304c\u81e8\u5e8a\u7814\u7a76\u3088\u308a\u660e\u3089\u304b\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u3088\u3063\u3066\u3001\uff12\u578b\u7cd6\u5c3f\u75c5\u306e\u75c5\u56e0\u3092\u7a76\u660e\u3057\u7cd6\u5c3f\u75c5\u6cbb\u7642\u85ac\u3092\u5275\u51fa\u3059\u308b\u306b\u306f\u3001\u81b5B\u7d30\u80de\u306b\u304a\u3051\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u306e\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u304c\u5fc5\u8981\u3067\u3059\u3002\u79c1\u305f\u3061\u306f\u3001\u5206\u5b50\u30b9\u30a4\u30c3\u30c1\u3067\u3042\u308bG\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7740\u76ee\u3057\u3001\u81b5B\u7d30\u80de\u3067\u30a4\u30f3\u30b9\u30ea\u30f3\u3092\u84c4\u3048\u3066\u3044\u308b\u5c0f\u80de(\u30a4\u30f3\u30b9\u30ea\u30f3\u9846\u7c92)\u306e\u52d5\u614b\u304c\u6642\u9593\u7684\u30fb\u7a7a\u9593\u7684\u306b\u3069\u306e\u3088\u3046\u306b\u5236\u5fa1\u3055\u308c\u3066\u3044\u308b\u306e\u304b\u3092\u89e3\u6790\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-10283ee9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"10283ee9\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-23814c85\" data-id=\"23814c85\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-245861ae elementor-widget elementor-widget-text-editor\" data-id=\"245861ae\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>\u3000<span style=\"font-family: arial, helvetica, sans-serif; color: #000000;\">G\u30bf\u30f3\u30d1\u30af\u8cea\u306f\u3001GTP\u578b\u304c\u6d3b\u6027\u578b(\u30b9\u30a4\u30c3\u30c1\u306e\u30aa\u30f3)\u3067GDP\u578b\u304c\u4e0d\u6d3b\u6027\u578b(\u30b9\u30a4\u30c3\u30c1\u306e\u30aa\u30d5)\u3068\u3053\u308c\u307e\u3067\u8003\u3048\u3089\u308c\u3066\u304d\u307e\u3057\u305f\u3002\u79c1\u305f\u3061\u306f\u3001GDP\u578b\u306eG\u30bf\u30f3\u30d1\u30af\u8cea(Rab27a)\u306b\u7d50\u5408\u3057\u3001\u4e0b\u6d41\u306b\u30b7\u30b0\u30ca\u30eb\u3092\u4f1d\u3048\u308b\u5206\u5b50(coronin3\u3001IQGAP1)\u3092\u4e16\u754c\u306b\u5148\u99c6\u3051\u3066\u767a\u898b\u3057\u307e\u3057\u305f\u3002\u79c1\u305f\u3061\u306f\u3001\u300cGDP\u578b\u4f9d\u5b58\u6027\u30a8\u30d5\u30a7\u30af\u30bf\u30fc\u300d\u306e\u6982\u5ff5\u3092\u63d0\u5531\u3057\u3001\u4f4e\u5206\u5b50\u91cfG\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u306f\u3069\u306e\u304f\u3089\u3044\u666e\u904d\u7684\u306a\u73fe\u8c61\u3067\u3042\u308b\u306e\u304b\u3092\u691c\u8a0e\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6c50bfa6 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6c50bfa6\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-54752210\" data-id=\"54752210\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1923de35 elementor-widget elementor-widget-image\" data-id=\"1923de35\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img fetchpriority=\"high\" decoding=\"async\" width=\"768\" height=\"549\" src=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-768x549.png\" class=\"attachment-medium_large size-medium_large wp-image-895\" alt=\"\" srcset=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-768x549.png 768w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-300x214.png 300w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-1024x732.png 1024w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-1536x1098.png 1536w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-2048x1464.png 2048w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-688111bf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"688111bf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7d6705db\" data-id=\"7d6705db\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5613955b elementor-widget elementor-widget-text-editor\" data-id=\"5613955b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-family: arial, helvetica, sans-serif; color: #000000;\">\u3000\u3055\u3089\u306b\u79c1\u305f\u3061\u306f\u3001\u958b\u53e3\u653e\u51fa\u306b\u3088\u308a\u7d30\u80de\u819c\u306b\u878d\u5408\u3057\u305f\u30a4\u30f3\u30b9\u30ea\u30f3\u9846\u7c92\u819c\u3092\u518d\u3073\u7d30\u80de\u5185\u306b\u53d6\u308a\u8fbc\u3080\u3053\u3068\u3067(\u30a8\u30f3\u30c9\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9)\u3001\u7d30\u80de\u306e\u5bb9\u7a4d\u3092\u5206\u6ccc\u5f8c\u3082\u4e00\u5b9a\u306b\u4fdd\u3064\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u660e\u3089\u304b\u306b\u3057\u307e\u3057\u305f\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u523a\u6fc0\u3067\u3042\u308b\u30b0\u30eb\u30b3\u30fc\u30b9\u306f\u3001\u540c\u6642\u306b\u30a8\u30f3\u30c9\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9\u306b\u95a2\u308f\u308b\u30bf\u30f3\u30d1\u30af\u8cea\u7fa4(coronin3\u3068Rab27a)\u3092\u8db3\u5834\u30bf\u30f3\u30d1\u30af\u8cea(IQGAP1)\u3092\u4ecb\u3057\u3066\u7d30\u80de\u819c\u8fd1\u508d\u306b\u30ea\u30af\u30eb\u30fc\u30c8\u3057\u307e\u3059\u3002\u30ea\u30af\u30eb\u30fc\u30c8\u3055\u308c\u305fcoronin3\u306f\u3001GDP\u578bRab27a\u3068\u7d50\u5408\u3059\u308b\u3053\u3068\u3067\u7d30\u80de\u9aa8\u683c(\u30a2\u30af\u30c1\u30f3)\u3092\u675f\u306d\u3001\u30a8\u30f3\u30c9\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9\u3092\u5236\u5fa1\u3059\u308b\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u3053\u308c\u306f\u3001GDP\u578b\u4f9d\u5b58\u6027\u30a8\u30d5\u30a7\u30af\u30bf\u30fc\u306e\u30b7\u30b0\u30ca\u30eb\u4f1d\u9054\u3092\u660e\u3089\u304b\u306b\u3057\u305f\u6700\u521d\u306e\u5831\u544a\u3067\u3059\u3002<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-329e6962 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"329e6962\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-527fdcf8\" data-id=\"527fdcf8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-43f4955e elementor-widget elementor-widget-image\" data-id=\"43f4955e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"768\" height=\"520\" src=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/2b530e80c7d0de90885e285c5d798063-768x520.png\" class=\"attachment-medium_large size-medium_large wp-image-896\" alt=\"\" srcset=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/2b530e80c7d0de90885e285c5d798063-768x520.png 768w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/2b530e80c7d0de90885e285c5d798063-300x203.png 300w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/2b530e80c7d0de90885e285c5d798063-1024x694.png 1024w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/2b530e80c7d0de90885e285c5d798063-1536x1041.png 1536w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/2b530e80c7d0de90885e285c5d798063-2048x1388.png 2048w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-722e585 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"722e585\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6dc94744\" data-id=\"6dc94744\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1c6dbde8 elementor-widget elementor-widget-text-editor\" data-id=\"1c6dbde8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-family: arial, helvetica, sans-serif; color: #000000;\">\u3000\u30b0\u30eb\u30b3\u30fc\u30b9\u306b\u3088\u308aRab27a\u304cGDP\u578b\u306b\u5909\u63db\u3055\u308c\u308b\u79c1\u305f\u3061\u306e\u7d50\u679c\u3068\u5408\u308f\u305b\u308b\u3068\u3001GTP\u578b\u3068GDP\u578b\u9593\u3067\u306eRab27a\u306e\u300c\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u300d\u306f\u3001\u81b5B\u7d30\u80de\u5185\u3067\u306e\u9846\u7c92\u819c\u306e\u300c\u30ea\u30b5\u30a4\u30af\u30ea\u30f3\u30b0\u300d\u3068\u540c\u671f\u3057\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u958b\u53e3\u653e\u51fa\u3001\u3042\u308b\u3044\u306f\u305d\u306e\u4e0a\u6d41\u306b\u4ecb\u5728\u3059\u308b\u5206\u6ccc\u6a5f\u69cb\u306b\u95a2\u3059\u308b\u5831\u544a\u306f\u679a\u6319\u306b\u3044\u3068\u307e\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u3057\u304b\u3057\u3001\u30a8\u30f3\u30c9\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9\u306e\u5236\u5fa1\u306f\u307b\u3068\u3093\u3069\u624b\u304c\u3064\u3051\u3089\u308c\u3066\u3044\u306a\u3044\u3068\u8a00\u3063\u3066\u904e\u8a00\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u79c1\u305f\u3061\u306f\u3001\u958b\u53e3\u653e\u51fa\u5f8c\u306e\u30a4\u30f3\u30b9\u30ea\u30f3\u9846\u7c92\u819c\u306e\u52d5\u614b\u3068\u305d\u306e\u5236\u5fa1\u6a5f\u69cb\u306e\u89e3\u660e\u304b\u3089\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u306e\u65b0\u3057\u3044\u5206\u6ccc\u5236\u5fa1\u6a5f\u69cb\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-654cdb9d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"654cdb9d\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-18f57afa\" data-id=\"18f57afa\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-17125d21 elementor-widget elementor-widget-image\" data-id=\"17125d21\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"768\" height=\"666\" src=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/c8856789ec11ab8b1013037cef6929f9-768x666.png\" class=\"attachment-medium_large size-medium_large wp-image-900\" alt=\"\" srcset=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/c8856789ec11ab8b1013037cef6929f9-768x666.png 768w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/c8856789ec11ab8b1013037cef6929f9-300x260.png 300w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/c8856789ec11ab8b1013037cef6929f9-1024x887.png 1024w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/c8856789ec11ab8b1013037cef6929f9-1536x1331.png 1536w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/c8856789ec11ab8b1013037cef6929f9.png 1785w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-11cff8fa elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"11cff8fa\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2b43cf73\" data-id=\"2b43cf73\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-191e89fc elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"191e89fc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-988a12b elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"988a12b\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-a6d4ff1\" data-id=\"a6d4ff1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-31707a1 elementor-widget elementor-widget-heading\" data-id=\"31707a1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-medium\"><a href=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco_wp\/?page_id=973\">2.\u3000\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3068\u81b5\u03b2\u7d30\u80de\u91cf\u306e\u8abf\u7bc0\u306b\u95a2\u4e0e\u3059\u308b\u7d30\u80de\u5185\u60c5\u5831\u4f1d\u9054\u6a5f\u69cb\u306e\u89e3\u6790<\/a><\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8cca8dc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8cca8dc\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-dd04abb\" data-id=\"dd04abb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bd9117d elementor-widget elementor-widget-text-editor\" data-id=\"bd9117d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-family: arial, helvetica, sans-serif; color: #000000;\">\u3000\u7cd6\u5c3f\u75c5\u306f\u30a4\u30f3\u30b9\u30ea\u30f3\u4f5c\u7528\u4e0d\u8db3\u306b\u3088\u308b\u6162\u6027\u306e\u9ad8\u8840\u7cd6\u72b6\u614b\u3092\u4e3b\u5fb4\u3068\u3059\u308b\u4ee3\u8b1d\u6027\u75be\u60a3\u3067\u3059\u3002\u7cd6\u5c3f\u75c5\u60a3\u8005\u6570\u306f\u98df\u751f\u6d3b\u306e\u5909\u5316\u3001\u30e9\u30a4\u30d5\u30b9\u30bf\u30a4\u30eb\u306e\u5909\u5316\u306b\u3088\u308a\u5168\u4e16\u754c\u7684\u306b\u5897\u52a0\u306e\u4e00\u9014\u3092\u305f\u3069\u3063\u3066\u3044\u307e\u3059\u3002\u4e16\u754c\u306e\u7cd6\u5c3f\u75c5\u4eba\u53e3\u306f2019\u5e74\u306b\u306f4\u51046000\u4e07\u4eba\u304c\u7f79\u60a3\u3057\u3066\u304a\u308a\u30012045\u5e74\u307e\u3067\u306b7\u5104\u4eba\u307e\u3067\u5897\u52a0\u3059\u308b\u3068\u63a8\u5b9a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u65e5\u672c\u306b\u304a\u3044\u3066\u3082\u3001\u7cd6\u5c3f\u75c5\u4e88\u5099\u8ecd\u3092\u5408\u308f\u305b\u3001\u60a3\u8005\u6570\u306f2000\u4e07\u4eba\u306b\u306e\u307c\u308a\u3001\u4eca\u5f8c\u3082\u62e1\u5927\u3057\u3066\u3044\u304f\u3068\u63a8\u6e2c\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u7cd6\u5c3f\u75c5\u306f\u4e3b\u306b\u3001\u81ea\u5df1\u514d\u75ab\u75be\u60a3\u3067\u3042\u308b1\u578b\u7cd6\u5c3f\u75c5\u3068\u3001\u666e\u6bb5\u304b\u3089\u306e\u751f\u6d3b\u7fd2\u6163\u304c\u5f15\u304d\u91d1\u3068\u306a\u308a\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u4e0d\u5168\u3084\u30a4\u30f3\u30b9\u30ea\u30f3\u4f5c\u7528\u4e0d\u8db3\u3092\u5f15\u304d\u8d77\u3053\u30592\u578b\u7cd6\u5c3f\u75c5\u306b\u5927\u5225\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u60a3\u8005\u6570\u306f2\u578b\u7cd6\u5c3f\u75c5\u306e\u307b\u3046\u304c\u5727\u5012\u7684\u306b\u591a\u304f\u3001\u65e5\u672c\u3067\u306f95% \u4ee5\u4e0a\u3092\u5360\u3081\u30012\u578b\u7cd6\u5c3f\u75c5\u306e\u4e88\u9632\u3068\u514b\u670d\u306f\u3001\u7126\u7709\u306e\u8ab2\u984c\u3068\u306a\u3063\u3066\u3044\u307e\u3059\u3002<\/span><br \/><span style=\"font-family: arial, helvetica, sans-serif; color: #000000;\">\u30002\u578b\u7cd6\u5c3f\u75c5\u306f\u3001\u81b5\u03b2\u7d30\u80de\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u6a5f\u80fd\u306e\u969c\u5bb3\u3084\u3001\u03b2\u7d30\u80de\u91cf\u306e\u4f4e\u4e0b\u304c\u5f15\u304d\u91d1\u3068\u306a\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3001\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u7cd6\u5c3f\u75c5\u306e\u767a\u75c7\u30fb\u9032\u884c\u3092\u98df\u3044\u6b62\u3081\u308b\u305f\u3081\u306b\u3001\u81b5\u03b2\u7d30\u80de\u6a5f\u80fd\u304a\u3088\u3073\u7d30\u80de\u91cf\u4f4e\u4e0b\u306e\u6291\u6b62\u3092\u76ee\u6307\u3057\u81b5\u03b2\u7d30\u80de\u6a5f\u80fd\u306e\u89e3\u6790\u3092\u884c\u3063\u3066\u304d\u307e\u3057\u305f\u3002\u65b9\u6cd5\u3068\u3057\u3066\u3001\u30de\u30a6\u30b9\u304a\u3088\u3073\u30e9\u30c3\u30c8\u3088\u308a\u81b5\u5cf6\u3092\u5358\u96e2\u3057\u305f\u3082\u306e\u3001\u304a\u3088\u3073\u81b5\u03b2\u7d30\u80de\u682a\u3092\u7528\u3044\u3001\u591a\u7a2e\u306e\u523a\u6fc0\u306b\u5bfe\u3059\u308b\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u53cd\u5fdc\u3084\u3001\u907a\u4f1d\u5b50\u30fb\u30bf\u30f3\u30d1\u30af\u8cea\u767a\u73fe\u306e\u89e3\u6790\u3001\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u52d5\u7269\u3084\u907a\u4f1d\u5b50\u7d44\u307f\u63db\u3048\u5b9f\u9a13\u306b\u3088\u308a\u3001\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u3084\u03b2\u7d30\u80de\u6a5f\u80fd\u7dad\u6301\u306b\u95a2\u308f\u308b\u5206\u5b50\u30fb\u7269\u8cea\u306e\u63a2\u7d22\u3084\u6a5f\u80fd\u89e3\u6790\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u307e\u3067\u306b\u3001\u4e2d\u6027\u8102\u8cea\u3067\u3042\u308b\u30b8\u30a2\u30b7\u30eb\u30b0\u30ea\u30bb\u30ed\u30fc\u30eb\u3092\u4ee3\u8b1d\u3059\u308b\u9175\u7d20\u3067\u3042\u308b\u30b8\u30a2\u30b7\u30eb\u30b0\u30ea\u30bb\u30ed\u30fc\u30eb\u30ad\u30ca\u30fc\u30bc\u304c\u30a4\u30f3\u30b9\u30ea\u30f3\u5206\u6ccc\u6a5f\u80fd\u3084\u03b2\u7d30\u80de\u5897\u6b96\u6a5f\u69cb\u306b\u91cd\u8981\u306a\u5f79\u5272\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3053\u3068\u3001\u5404\u7a2e\u5929\u7136\u7269\u306b\u542b\u6709\u3055\u308c\u308b\u30d5\u30e9\u30dc\u30ce\u30a4\u30c9\u6210\u5206\u304c\u81b5\u03b2\u7d30\u80de\u6a5f\u80fd\u7dad\u6301\u306b\u5bc4\u4e0e\u3059\u308b\u3053\u3068\u306a\u3069\u3092\u898b\u51fa\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u7814\u7a76\u3092\u901a\u3058\u03b2\u7d30\u80de\u6a5f\u80fd\u7dad\u6301\u306b\u3088\u308b\u3001\u81b5\u03b2\u7d30\u80de\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u305f\u306a\u7cd6\u5c3f\u75c5\u767a\u75c7\u4e88\u9632\u6cd5\u3001\u6cbb\u7642\u6cd5\u306e\u958b\u767a\u3092\u76ee\u6307\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-190057e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"190057e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fa1086d\" data-id=\"fa1086d\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9cb586a elementor-widget elementor-widget-image\" data-id=\"9cb586a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"790\" height=\"373\" src=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/05\/image.png\" class=\"attachment-large size-large wp-image-1446\" alt=\"\" srcset=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/05\/image.png 891w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/05\/image-300x142.png 300w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/05\/image-768x363.png 768w\" sizes=\"(max-width: 790px) 100vw, 790px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-deff9d3 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"deff9d3\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d4ed68a\" data-id=\"d4ed68a\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-eab245c elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"eab245c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ee512f5 elementor-section-stretched elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ee512f5\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;stretch_section&quot;:&quot;section-stretched&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9830933\" data-id=\"9830933\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1f0f08d elementor-widget elementor-widget-heading\" data-id=\"1f0f08d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<span class=\"elementor-heading-title elementor-size-medium\"><a href=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco_wp\/?page_id=978\">3.\u3000\u809d\u7dda\u7dad\u75c7\u767a\u75c7\u306b\u95a2\u4e0e\u3059\u308b\u7d30\u80de\u5185\u60c5\u5831\u4f1d\u9054\u6a5f\u69cb\u306e\u89e3\u6790\u3068\u75be\u75c5\u4e88\u9632\u3078\u306e\u5fdc\u7528<\/a><\/span>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-583747c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"583747c\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-54533eb\" data-id=\"54533eb\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0e172c0 elementor-widget elementor-widget-text-editor\" data-id=\"0e172c0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"color: #000000; font-family: arial, helvetica, sans-serif;\">\u3000\u809d\u975e\u5b9f\u8cea\u7d30\u80de\u306e\u4e00\u3064\u3067\u3042\u308b\u809d\u661f\u7d30\u80de\uff08Hepatic stellate cell: HSC\uff09\u306f\u3001\u809d\u50b7\u5bb3\u6642\u306b\u6d3b\u6027\u5316\u3055\u308c\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u7523\u751f\u30fb\u5206\u6ccc\u3059\u308b\u7b4b\u7dda\u7dad\u82bd\u7d30\u80de\u69d8\u306e\u5f62\u614b\u3092\u793a\u3057\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u6d3b\u6027\u578bHSC\u306f\u809d\u7dda\u7dad\u5316\u306e\u8cac\u4efb\u7d30\u80de\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u73fe\u72b6\u3001\u9032\u884c\u3057\u305f\u809d\u7dda\u7dad\u5316\u306e\u6cbb\u7642\u306f\u96e3\u3057\u3044\u3068\u3055\u308c\u308b\u304c\u3001\u9759\u6b62\u578bHSC\u304c\u30b3\u30e9\u30fc\u30b2\u30f3\u306a\u3069\u306e\u7d30\u80de\u5916\u57fa\u8cea\u3092\u5206\u89e3\u3059\u308bmatrix metalloproteinase\uff08MMP\uff09\u3092\u5206\u6ccc\u3059\u308b\u3053\u3068\u304b\u3089\u3001\u6d3b\u6027\u578bHSC\u3092\u9759\u6b62\u578bHSC\u3078\u3068\u8131\u6d3b\u6027\u5316\u3067\u304d\u308c\u3070\u3001\u809d\u7dda\u7dad\u5316\u3082\u6cbb\u7642\u53ef\u80fd\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u307e\u3059\u3002<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3917dd7 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3917dd7\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-266e040\" data-id=\"266e040\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8d9ab92 elementor-widget elementor-widget-image\" data-id=\"8d9ab92\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"790\" height=\"349\" src=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-1-1024x453.png\" class=\"attachment-large size-large wp-image-1044\" alt=\"\" srcset=\"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-1-1024x453.png 1024w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-1-300x133.png 300w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-1-768x340.png 768w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-1-1536x680.png 1536w, https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmaco\/wp-content\/uploads\/2021\/04\/795316b92fc766b0181f6fef074f03fa-1.png 1577w\" sizes=\"(max-width: 790px) 100vw, 790px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-d33aa84 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d33aa84\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-16bc625\" data-id=\"16bc625\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-705ddd6 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"705ddd6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span 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