1. Iwao, Y., Hiraike, M., Kragh-Hansen, U., Kawai, K., Suenaga, A., Maruyama, T., and Otagiri, M. "Altered chain-length and glycosylation modify the pharmacokinetics of human serum albumin," Biochim Biophys Acta 1794 (2009):634-41.
  2. Taguchi, K., Maruyama, T., Iwao, Y., Sakai, H., Kobayashi, K., Horinouchi, H., Tsuchida, E., Kai, T., and Otagiri, M. "Pharmacokinetics of single and repeated injection of hemoglobin-vesicles in hemorrhagic shock rat model," J Control Release (2009): in press.
  1. Itoh, Y., Shimazu, A., Sadzuka, Y., Sonobe, T., and Itai, S. "Novel method for stratum corneum pore size determination using positron annihilation lifetime spectroscopy," Int J Pharm 358 (2008): 91-5.
  2. Kamiya, S., Yamada, M., Kurita, T., Miyagishima, A., Arakawa, M., and Sonobe, T. "Preparation and stabilization of nifedipine lipid nanoparticles," Int J Pharm 354 (2008): 242-7.
  3. Nakamori, T., Miyagishim, A., Nozawa, Y., Sadzuka, Y., and Sonobe, T. "Influence of load on particle size distribution of lactose-crystalline cellulose mixed powder," Int J Pharm 354 (2008): 255-9.
  4. Sadzuka, Y., Hatakeyama, H., Daimon, T., and Sonobe, T. "Screening of biochemical modulator by tumor cell permeability of doxorubicin," Int J Pharm 354 (2008): 63-9.
  5. Sadzuka, Y., Nakagawa, K., Yoshioka, H., and Sonobe, T. "A liposomal formulation study of 2,7-dichlorodihydrofluorescein for detection of reactive oxygen species," Int J Pharm 356 (2008): 300-5.
  6. Mizumoto, T., Tamura, T., Kawai, H., Kajiyama, A., and Itai, S. "Formulation design of an oral, fast-disintegrating dosage form containing taste-masked particles of famotidine," Chem Pharm Bull (Tokyo) 56 (2008): 946-50.
  7. Mizumoto, T., Tamura, T., Kawai, H., Kajiyama, A., and Itai, S. "Formulation design of taste-masked particles, including famotidine, for an oral fast-disintegrating dosage form," Chem Pharm Bull (Tokyo) 56 (2008): 530-5.
  8. Iwao, Y., Nakajou, K., Nagai, R., Kitamura, K., Anraku, M., Maruyama, T., and Otagiri, M. "CD36 is one of important receptors promoting renal tubular injury by advanced oxidation protein products," Am J Physiol Renal Physiol 295 (2008): F1871-80.
  9. Nagai, R., Fujiwara, Y., Mera, K., Motomura, K., Iwao, Y., Tsurushima, K., Nagai, M., Takeo, K., Yoshitomi, M., Otagiri, M., and Ikeda, T. "Usefulness of antibodies for evaluating the biological significance of AGEs," Ann N Y Acad Sci 1126 (2008): 38-41.
  1. Hayashi, T., Kanbe, H., Okada, M., Kawase, I., Ikeda, Y., Onuki, Y., Kaneko, T., and Sonobe, T. "In vitro and in vivo sustained-release characteristics of theophylline matrix tablets and novel cluster tablets," Int J Pharm 341 (2007): 105-13.
  2. Kanbe, H., Hayashi, T., Onuki, Y., and Sonobe, T. "Manufacture of fine spherical granules by an extrusion/spheronization method," Int J Pharm 337 (2007): 56-62.
  3. Sadzuka, Y., Iwasaki, F., Sugiyama, I., Horiuchi, K., Hirano, T., Ozawa, H., Kanayama, N., and Sonobe, T. "Study on liposomalization of zinc-coproporphyrin I as a novel drug in photodynamic therapy," Int J Pharm 338 (2007): 306-9.
  4. Sadzuka, Y., and Sonobe, T. "Anserine induced advantage effects on the antitumor activity of doxorubicin," Food Chem Toxicol 45 (2007): 985-9.
  5. Sugiyama, I., and Sadzuka, Y. "Characterization of novel mixed polyethyleneglycol modified liposomes," Biol Pharm Bull 30 (2007): 208-11.
  6. Iwao, Y., Hiraike, M., Kragh-Hansen, U., Mera, K., Noguchi, T., Anraku, M., Kawai, K., Maruyama, T., and Otagiri, M. "Changes of net charge and alpha-helical content affect the pharmacokinetic properties of human serum albumin," Biochim Biophys Acta 1774 (2007): 1582-90.
  7. Nagai, R., Mera, K., Nakajou, K., Fujiwara, Y., Iwao, Y., Imai, H., Murata, T., and Otagiri, M. "The ligand activity of AGE-proteins to scavenger receptors is dependent on their rate of modification by AGEs," Biochim Biophys Acta 1772 (2007): 1192-8.
  8. Zsila, F., and Iwao, Y. "The drug binding site of human alpha1-acid glycoprotein: insight from induced circular dichroism and electronic absorption spectra," Biochim Biophys Acta 1770 (2007): 797-809.
  1. Sadzuka, Y., Sugiyama, I., Tsuruda, T., and Sonobe, T. "Characterization and cytotoxicity of mixed polyethyleneglycol modified liposomes containing doxorubicin," Int J Pharm 312 (2006): 83-9.
  2. Sadzuka, Y., Tokutomi, K., Iwasaki, F., Sugiyama, I., Hirano, T., Konno, H., Oku, N., and Sonobe, T. "The phototoxicity of photofrin was enhanced by PEGylated liposome in vitro," Cancer Lett 241 (2006): 42-8.
  3. Sadzuka, Y., Sugiyama, T., Nagamine, M., Umegaki, K., and Sonobe, T. "Efficacy of theanine is connected with theanine metabolism by any enzyme, not only drug metabolizing enzymes," Food Chem Toxicol 44 (2006): 286-92.
  4. Kamiya, S., Nozawa, Y., Miyagishima, A., Kurita, T., Sadzuka, Y., and Sonobe, T. "Physical characteristics of freeze-dried griseofulvin-lipids nanoparticles," Chem Pharm Bull (Tokyo) 54 (2006): 181-4.
  5. Iwao, Y., Anraku, M., Hiraike, M., Kawai, K., Nakajou, K., Kai, T., Suenaga, A., and Otagiri, M. "The structural and pharmacokinetic properties of oxidized human serum albumin, advanced oxidation protein products (AOPP)," Drug Metab Pharmacokinet 21 (2006): 140-6.
  6. Iwao, Y., Anraku, M., Yamasaki, K., Kragh-Hansen, U., Kawai, K., Maruyama, T., and Otagiri, M. "Oxidation of Arg-410 promotes the elimination of human serum albumin," Biochim Biophys Acta 1764 (2006): 743-9.
  7. Kragh-Hansen, U., Watanabe, H., Nakajou, K., Iwao, Y., and Otagiri, M. "Chain length-dependent binding of fatty acid anions to human serum albumin studied by site-directed mutagenesis," J Mol Biol 363 (2006): 702-12.