{"id":156,"date":"2020-05-20T14:45:51","date_gmt":"2020-05-20T05:45:51","guid":{"rendered":"http:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng_wp\/?page_id=156"},"modified":"2026-03-11T12:49:57","modified_gmt":"2026-03-11T03:49:57","slug":"4-%e6%a5%ad%e7%b8%be","status":"publish","type":"page","link":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng\/?page_id=156","title":{"rendered":"4. \u7814\u7a76\u696d\u7e3e"},"content":{"rendered":"\n

2026\u5e74<\/mark><\/h2>\n\n\n\n
    \n
  1. Natsuki Takahashi, Miho Inoue, Ryuka Furuya, Takayuki Terukina, Hiromu Kondo*, Impact of disintegrants on the structure and disintegration of hydroxypropyl methylcellulose-based amorphous solid dispersion tablets. J Pharm Sci <\/strong><\/em>(IF:3.8) 2026;115(4)<\/strong>:104194 https:\/\/doi.org\/10.1016\/j.xphs.2026.104194<\/a><\/li>\n\n\n\n
  2. Shingo Iioka, Yuta Hatanaka, Takayuki Terukina, Takanori Kanazawa, Hiromu Kondo*, Protectant Selection for Freeze Dry of Functional Peptide-Assembled Polymer Nanoparticles Composed of Methoxy Poly Ethylene Glycol \u03b5-poly Caprolactone as a Carrier of Oligonucleotides. J Pharm Innov<\/em><\/strong><\/strong><\/em> (IF:2.7) 2026;21<\/strong>:285 https:\/\/doi.org\/10.1007\/s12247-026-10489-y<\/a><\/li>\n<\/ol>\n\n\n\n

    2025\u5e74<\/mark><\/h2>\n\n\n\n

    Publications<\/strong><\/p>\n\n\n\n

      \n
    1. Shingo Iioka, Takanori Kanazawa, Hiromu Kondo*, Design of functional peptide-assembled polymer nanoparticles with uniform dispersion for oligonucleotide delivery to the brain and spinal cord via the nose-to-brain route. J Drug Deliv Sci Tech<\/em><\/strong><\/strong><\/em> (IF:4.9) 2025;105<\/strong>:106617 https:\/\/doi.org\/10.1016\/j.jddst.2025.106617<\/a><\/li>\n\n\n\n
    2. Naoki Yoshihara, Ryota Kimata, Takayuki Terukina, Hiromu Kondo*, Consistent dry process for preparing functional particles with novel coating using two-step melt granulation. Powder Technol<\/em><\/strong> (IF:4.6) 2025;465<\/strong>:121297 https:\/\/doi.org\/10.1016\/j.powtec.2025.121297<\/a><\/li>\n<\/ol>\n\n\n\n

      \u53d7\u8cde<\/strong><\/p>\n\n\n\n

        \n
      1. \u85e4\u4e95\u53ef\u601c\uff08B4\uff09\u3001\u4ee4\u548c6\u5e74\u5ea6\u85e4\u679d\u5e02\u5730\u57df\u653f\u7b56\u7814\u7a76\u30fb\u5275\u9020\u4e8b\u696d\u6210\u679c\u5831\u544a\u4f1a \u6700\u512a\u79c0\u8cde\u300c\u8336\u306e\u9999\u6c17\u6210\u5206\u3092\u6c34\u4e2d\u6301\u7d9a\u653e\u6563\u3067\u304d\u308b\u200b\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u30b7\u30fc\u30c8\u306e\u958b\u767a\u200b\u300d<\/li>\n\n\n\n
      2. \u5927\u585a\u5343\u7d18\uff08M2\uff09\u3001\u65e5\u672c\u85ac\u5264\u5b66\u4f1a\u6c38\u4e95\u8ca1\u56e3\u5927\u5b66\u9662\u5b66\u751f\u30b9\u30ab\u30e9\u30b7\u30c3\u30d7\u300c\u540c\u8ef8\u30a8\u30ec\u30af\u30c8\u30ed\u30b9\u30d4\u30cb\u30f3\u30b0\u6cd5\u3092\u7528\u3044\u305f\u85ac\u7269\u653e\u51fa\u5236\u5fa1\u30b3\u30a2\u30b7\u30a7\u30eb\u30d5\u30a1\u30a4\u30d0\u30fc\u306e\u8abf\u88fd\u300d<\/li>\n\n\n\n
      3. \u82b9\u6fa4\u672a\u6765\uff08B6\uff09\u3001\u65e5\u672c\u85ac\u5264\u5b66\u4f1a\u6c38\u4e95\u8ca1\u56e3\u5b66\u90e8\u5b66\u751f\u4e03\u3064\u661f\u85ac\u5e2b\u5968\u52b1\u8cde\u300c\u30c1\u30ad\u30bd\u30c8\u30ed\u30d4\u30fc\u6027\u30cf\u30a4\u30c9\u30ed\u30b2\u30eb\u3092\u5229\u7528\u3057\u305f\u5674\u9727\u6027\u3068\u6ede\u7559\u6027\u3092\u4e21\u7acb\u3059\u308b\u30b9\u30d7\u30ec\u30fc\u88fd\u5264\u306e\u958b\u767a\u300d<\/li>\n\n\n\n
      4. \u5927\u585a\u5343\u7d18\uff08M2\uff09\u3001\u65e5\u672c\u85ac\u5264\u5b66\u4f1a\u7b2c40\u5e74\u4f1a \u6700\u512a\u79c0\u767a\u8868\u8005\u8cde\u300c\u540c\u8ef8\u30a8\u30ec\u30af\u30c8\u30ed\u30b9\u30d4\u30cb\u30f3\u30b0\u6cd5\u3092\u7528\u3044\u305f\u85ac\u7269\u653e\u51fa\u5236\u5fa1\u30b3\u30a2\u30b7\u30a7\u30eb\u30d5\u30a1\u30a4\u30d0\u30fc\u306e\u8abf\u88fd\u300d<\/li>\n\n\n\n
      5. \u5ca9\u5ca1\u91ce\u9ea6\uff08M2\uff09\u3001\u7b2c71\u56de\u65e5\u672c\u85ac\u5b66\u4f1a\u6771\u6d77\u652f\u90e8\u5927\u4f1a \u5b66\u751f\u512a\u79c0\u767a\u8868\u8cde\u300c\u30b7\u30e7\u7cd6\u8102\u80aa\u9178\u30a8\u30b9\u30c6\u30eb\u3068\u9ad8\u5206\u5b50\u57fa\u5264\u304c\u30af\u30eb\u30af\u30df\u30f3\u306e\u6eb6\u89e3\u6027\u6539\u5584\u306b\u53ca\u307c\u3059\u5f71\u97ff\u300d<\/li>\n\n\n\n
      6. \u6728\u5168\u5d1a\u592a\u3001\u7b2c50\u56de\u88fd\u5264\u30fb\u5275\u5264\u30bb\u30df\u30ca\u30fc Postdoctoral Presentation Award\u300c\u6eb6\u878d\u9020\u7c92\u306b\u3088\u308b\u85ac\u7269\u9ad8\u542b\u6709\u7403\u5f62\u7c92\u5b50\u88fd\u9020\u6280\u8853\u306e\u958b\u767a\u3068\u6a5f\u80fd\u6027\u4ed8\u4e0e\u300d<\/li>\n\n\n\n
      7. \u7551\u4e2d\u53cb\u592a\u3001\u7b2c50\u56de\u88fd\u5264\u30fb\u5275\u5264\u30bb\u30df\u30ca\u30fc Postdoctoral Presentation Award\u300c\u7570\u306a\u308b\u5206\u5b50\u9593\u76f8\u4e92\u4f5c\u7528\u69d8\u5f0f\u3092\u6709\u3059\u308b\u85ac\u7269-\u85ac\u7269\u30b3\u30a2\u30e2\u30eb\u30d5\u30a1\u30b9\u306e\u8a2d\u8a08\u3068\u819c\u900f\u904e\u6027\u8a55\u4fa1\u306b\u95a2\u3059\u308b\u7814\u7a76\u300d<\/li>\n<\/ol>\n\n\n\n

        \u5916\u90e8\u8cc7\u91d1\u7372\u5f97\uff08\u7af6\u4e89\u7684\u8cc7\u91d1\u306e\u307f\u8a18\u8f09\uff09<\/strong><\/p>\n\n\n\n

          \n
        1. \u8fd1\u85e4\u5553\uff08\u4ee3\u8868\uff09\u3001\u7167\u559c\u540d\u5b5d\u4e4b\u3001\u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76\uff08C\uff09\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
        2. \u7167\u559c\u540d\u5b5d\u4e4b\uff08\u4ee3\u8868\uff09\u3001\u79d1\u7814\u8cbb \u82e5\u624b\u7814\u7a76\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
        3. \u7551\u4e2d\u53cb\u592a\uff08\u4ee3\u8868\uff09\u3001\u79d1\u7814\u8cbb \u82e5\u624b\u7814\u7a76\uff08\u65b0\u898f\uff09<\/li>\n<\/ol>\n\n\n\n

          2024\u5e74<\/mark><\/h2>\n\n\n\n

          Publications<\/strong><\/p>\n\n\n\n

            \n
          1. Kaede Osanai, Shunske Aoki, Chihiro Otsuka, Hirotaka Watanabe, Haruhiko Hikichi, Takayuki Terukina, Hiromu Kondo*, Effect of Fluid Paraffin on the Formulation Properties of Pressure Sensitive Adhesive Formulations Containing Diclofenac Sodium. AAPS PharmSciTech<\/strong><\/em> (IF:4.026) 2024;25<\/strong>:244 https:\/\/doi.org\/10.1208\/s12249-024-02959-8<\/a><\/li>\n\n\n\n
          2. Ryota Kimata, Naoki Yoshihara, Yuya Tomita, Takayuki Terukina, Hiromu Kondo*, Polymer Characteristics for Drug Layering on Particles Using a Novel Melt Granulation Technology, MALCORE\u00ae<\/sup>. AAPS PharmSciTech<\/em><\/strong>  <\/em>(IF:4.026) 2024;25<\/strong>:81 https:\/\/doi.org\/10.1208\/s12249-024-02798-7<\/a><\/li>\n\n\n\n
          3. Yusuke Oe, Masanori Kobayashi, Takayuki Yoshida, Hiroyuki Kojima, Takayuki Terukina, Hiromu Kondo*, Injectable testosterone PLGA microsphere with different characteristics: effect of preparation method (paddle mixing versus microfluidic device), Pharmaceutical Development and Technology<\/em><\/strong> (IF:3.400) 2024;29<\/strong>:482-491. https:\/\/doi.org\/10.1080\/10837450.2024.2348580<\/a><\/li>\n\n\n\n
          4. Takayuki Oguma, Takanori Kanazawa*, Yukiko K. Kaneko*, Ren Sato, Miku Serizawa, Akira Ooka, Momoka Yamaguchi, Tomohisa Ishikawa, Hiromu Kondo, Effects of phospholipid type and particle size on lipid nanoparticle distribution in vivo and in pancreatic islets. J Control Release<\/strong><\/em> (IF:11.467), 2024;373<\/strong>:917-928. https:\/\/doi.org\/10.1016\/j.jconrel.2024.07.059<\/a><\/li>\n<\/ol>\n\n\n\n

            \u53d7\u8cde<\/strong><\/p>\n\n\n\n

              \n
            1. \u98ef\u5ca1\u771f\u543e\uff08D4\uff09\u3001\u65e5\u672c\u85ac\u5264\u5b66\u4f1a\u7b2c39\u5e74\u4f1a\u5b66\u751f\u4e3b\u50ac\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0SNPEE2024\u512a\u79c0\u767a\u8868\u8005\u8cde\u300c\u30d6\u30ed\u30c3\u30af\u30b3\u30dd\u30ea\u30de\u30fc\/\u6a5f\u80fd\u6027\u30da\u30d7\u30c1\u30c9\u5171\u96c6\u5408\u5316\u30ca\u30ce\u7c92\u5b50\u306e\u8a2d\u8a08\u3068Nose-to-Brain\u578b\u6838\u9178\u30c7\u30ea\u30d0\u30ea\u30fc\u3078\u306e\u5fdc\u7528\u300d<\/li>\n\n\n\n
            2. \u98ef\u5ca1\u771f\u543e\uff08D4\uff09\u3001\u65e5\u672c\u85ac\u5264\u5b66\u4f1a\u6c38\u4e95\u8ca1\u56e3\u5927\u5b66\u9662\u5b66\u751f\u30b9\u30ab\u30e9\u30b7\u30c3\u30d7\u300c\u30d6\u30ed\u30c3\u30af\u30b3\u30dd\u30ea\u30de\u30fc\/\u6a5f\u80fd\u6027\u30da\u30d7\u30c1\u30c9\u5171\u96c6\u5408\u5316\u30ca\u30ce\u7c92\u5b50\u306e\u8a2d\u8a08\u3068Nose-to-Brain\u578b\u6838\u9178\u30c7\u30ea\u30d0\u30ea\u30fc\u3078\u306e\u5fdc\u7528\u300d<\/li>\n\n\n\n
            3. \u7167\u559c\u540d\u5b5d\u4e4b\u30012024\u5e74\u5ea6 \u65e5\u672c\u85ac\u5b66\u4f1a\u6771\u6d77\u652f\u90e8\u5b66\u8853\u5968\u52b1\u8cde \u300c\u30ec\u30aa\u30ed\u30b8\u30fc\u89e3\u6790\u306e\u5fdc\u7528\u306b\u57fa\u3065\u304f\u88fd\u5264\u8a2d\u8a08\u3068\u8a55\u4fa1\u300d<\/li>\n\n\n\n
            4. \u798f\u6e80\u65e9\u7d00\uff08B6\uff09\u3001\u7b2c70\u56de\u65e5\u672c\u85ac\u5b66\u4f1a\u6771\u6d77\u652f\u90e8\u5927\u4f1a \u5b66\u751f\u512a\u79c0\u767a\u8868\u8cde\u300c\u30a4\u30c8\u30e9\u30b3\u30ca\u30be\u30fc\u30eb\u542b\u6709\u56fa\u4f53\u5206\u6563\u4f53\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u30b7\u30fc\u30c8\u306e\u8abf\u88fd\u3068\u8a55\u4fa1\u300d<\/li>\n\n\n\n
            5. \u5927\u585a\u5343\u7d18\uff08M1\uff09\u3001\u7b2c49\u56de\u88fd\u5264\u30fb\u5275\u5264\u30bb\u30df\u30ca\u30fc Best Poster Presentation Award\u300cBCS\u30af\u30e9\u30b9\u2162\u5316\u5408\u7269\u542b\u6709\u7c98\u819c\u4ed8\u7740\u6027\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u30b7\u30fc\u30c8\u306e\u8a2d\u8a08\u3068\u7d4c\u53e3\u5438\u53ce\u6027\u6539\u5584\u306e\u691c\u8a0e\u300d<\/li>\n\n\n\n
            6. \u98ef\u5ca1\u771f\u543e\uff08D4\uff09\u3001\u7b2c29\u56de \u5275\u5264\u30d5\u30a9\u30fc\u30e9\u30e0 \u82e5\u624b\u7814\u7a76\u4f1a \u6700\u512a\u79c0\u767a\u8868\u8cde\u300c\u6a5f\u80fd\u6027\u30da\u30d7\u30c1\u30c9\u5171\u96c6\u5408\u5316\u30d6\u30ed\u30c3\u30af\u30b3\u30dd\u30ea\u30de\u30fc\u30ca\u30ce\u7c92\u5b50\u306e\u51cd\u7d50\u4e7e\u71e5\u306b\u304a\u3051\u308b\u51cd\u7d50\u4fdd\u8b77\u5264\u306e\u9078\u5b9a\u3068\u7269\u7406\u5316\u5b66\u7684\u7279\u6027\u8a55\u4fa1\u300d<\/li>\n\n\n\n
            7. \u6728\u5168\u5d1a\u592a\u3001\u7b2c32\u56deDDS\u30ab\u30f3\u30d5\u30a1\u30e9\u30f3\u30b9 Postdoctoral Presentation Award\u300c\u4e8c\u5de5\u7a0b\u6eb6\u878d\u9020\u7c92\u306b\u3088\u308b\u85ac\u7269\u9ad8\u542b\u6709\u7403\u5f62\u7c92\u5b50\u88fd\u9020\u6280\u8853\u306e\u958b\u767a\u300d<\/li>\n<\/ol>\n\n\n\n

              \u5916\u90e8\u8cc7\u91d1\u7372\u5f97\uff08\u7af6\u4e89\u7684\u8cc7\u91d1\u306e\u307f\u8a18\u8f09\uff09<\/strong><\/h4>\n\n\n\n
                \n
              1. \u8fd1\u85e4\u5553\uff08\u4ee3\u8868\uff09\u3001\u7167\u559c\u540d\u5b5d\u4e4b\u3001\u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76\uff08C\uff09\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
              2. \u7167\u559c\u540d\u5b5d\u4e4b\uff08\u4ee3\u8868\uff09\u3001\u79d1\u7814\u8cbb \u82e5\u624b\u7814\u7a76\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
              3. \u98ef\u5ca1\u771f\u543e\uff08\u4ee3\u8868\uff09\u3001\u7279\u5225\u7814\u7a76\u54e1\u5968\u52b1\u8cbb\uff08DC1\uff09\uff08\u7d99\u7d9a\uff09<\/li>\n<\/ol>\n\n\n\n

                2023\u5e74<\/mark><\/mark><\/h2>\n\n\n\n

                Publications<\/h4>\n\n\n\n
                  \n
                1. Ryota Kimata, Naoki Yoshihara, Takayuki Terukina, Takanori Kanazawa, Hiromu Kondo*, Impact of properties of hydrated silicon dioxide as core material on the characteristics of drug-containing particles prepared by the 2-step process melt granulation technology, MALCORE\u00ae<\/sup>. AAPS PharmSciTech<\/em><\/strong>  <\/em>(IF:4.026) 2023;24<\/strong>:28 https:\/\/doi.org\/10.1208\/s12249-022-02492-6<\/a><\/li>\n\n\n\n
                2. Sorato Ikeda, Masanori Kobayashi, Soken Aoki, Takayuki Terukina, Takanori Kanazawa, Hiroyuki Kojima, Hiromu Kondo*, 3D-Printed Fast-Dissolving Oral Dosage Forms via Fused Deposition Modeling Based on Sugar Alcohol and Poly(Vinyl Alcohol)\u2014Preparation, Drug Release Studies and In Vivo<\/em> Oral Absorption. Pharmaceutics<\/em><\/strong> <\/em>(IF:6.525) 2023;15<\/strong>(2):395 https:\/\/doi.org\/10.3390\/pharmaceutics15020395<\/a><\/li>\n\n\n\n
                3. Takayuki Terukina, Jun Tanaka, Yumi Takayama, Kaede Osanai, Shusuke Kino, Takanori Kanazawa, Hiromu Kondo*, Sangelose-based gels and films: effect of glycerol and \u03b1-cyclodextrin and pharmaceutical application. Drug Development and Industrial Pharmacy<\/strong><\/em> (IF:3.727) 2023;49<\/strong>(1):75-83. https:\/\/doi.org\/10.1080\/03639045.2023.2182127<\/a><\/li>\n\n\n\n
                4. Takayuki Terukina, Saori Muramoto, Kaede Osanai, Miho Inoue, Hirotaka Watanabe, Yuki Hakamata, Haruhiko Hikichi, Hiromu Kondo: Effect of Liquid Paraffin on the Characteristics of Pressure-Sensitive Adhesives Applied to Medical Tape Formulations. Journal of Pharmaceutical Innovation <\/strong><\/em>(IF:2.538) 2023;18<\/strong>:2110-2119. https:\/\/doi.org\/10.1007\/s12247-023-09777-8<\/a><\/li>\n\n\n\n
                5. Naoki Yoshihara, Ryota Kimata, Takayuki Terukina, Hiromu Kondo: Effect of Manufacturing Conditions on Particle Characteristics in the Drug-Layering Process of a Novel Melt Granulation Technology, MALCORE\u00ae<\/sup>, Using a Design of Experiments.  Journal of Pharmaceutical Innovation <\/strong><\/em>(IF:2.538) 2023;18<\/strong>:2158-2169. https:\/\/doi.org\/10.1007\/s12247-023-09777-8<\/a><\/li>\n\n\n\n
                6. Hiroyuki Kojima, Takayuki Yoshida, Hiromu Kondo, Kazuhiro Sako: Drug Extended-Release System Utilizing Micelle Formation of Highly Water-Soluble Drugs and a Counter Polymer. Molecular Pharmaceutics<\/strong><\/em> (IF: 5.364) 2023;20<\/strong>:6056-6065. https:\/\/doi.org\/10.1021\/acs.molpharmaceut.3c00377<\/a><\/li>\n<\/ol>\n\n\n\n

                  Revi<\/strong>ew article\/Book chapter<\/h4>\n\n\n\n

                  \u90a6\u6587\u8ad6\u6587\u30fb\u7dcf\u8aac\u30fb\u8457\u66f8<\/h4>\n\n\n\n
                    \n
                  1. \u91d1\u6ca2\u8cb4\u61b2\u3001\u975e\u4fb5\u8972\u7684\u6838\u9178\u30c7\u30ea\u30d0\u30ea\u30fc\u3001\u7279\u96c6\u300c\u6838\u9178\u533b\u85ac\u3068\u795e\u7d4c\u75be\u60a3\u300d\u3001Clinical Neuroscience\u30012023:41(5);671-674<\/li>\n\n\n\n
                  2. \u91d1\u6ca2\u8cb4\u61b2\u3001Nose-to-Brain\u7d4c\u8def\u306b\u7740\u76ee\u3057\u305fCNS\u75be\u60a3\u3092\u6a19\u7684\u3068\u3059\u308bDDS\u3001\u88fd\u5264\u8a2d\u8a08\u30fb\u88fd\u9020\u6280\u8853 BASIC & FRONTEER\uff08\u76e3\u4fee\uff1a\u5ca1\u7530\u5f18\u6643\u3001\u5ddd\u4e0a\u4e98\u4f5c\uff09\u30012023;525-537<\/li>\n<\/ol>\n\n\n\n

                    \u53d7\u8cde<\/h4>\n\n\n\n
                      \n
                    1. \u9577\u5185\u6953\uff08M2\uff09\u3001\u65e5\u672c\u85ac\u5264\u5b66\u4f1a\u7b2c38\u5e74\u4f1a\u6700\u512a\u79c0\u767a\u8868\u8005\u8cde\u300c\u30c6\u30fc\u30d7\u5264\u306b\u304a\u3051\u308bSIS\u30d6\u30ed\u30c3\u30af\u5171\u91cd\u5408\u4f53\u3092\u7528\u3044\u305f\u7c98\u7740\u5c64\u306e\u7269\u6027\u306b\u53ca\u307c\u3059\u6d41\u52d5\u30d1\u30e9\u30d5\u30a3\u30f3\u306e\u5f71\u97ff\u300d<\/li>\n\n\n\n
                    2. \u771f\u91ce\u7d50\u5948\uff08B6\uff09\u3001\u7b2c39\u56de\u65e5\u672cDDS\u5b66\u4f1a\u512a\u79c0\u767a\u8868\u8cde\u300c\u30de\u30a4\u30af\u30ed\u6d41\u4f53\u30c7\u30d0\u30a4\u30b9\u6cd5\u306b\u3088\u308a\u8abf\u88fd\u3057\u305fDOPC\u30ca\u30ce\u7c92\u5b50\u306e\u5f62\u614b\u306b\u53ca\u307c\u3059\u30b3\u30ec\u30b9\u30c6\u30ed\u30fc\u30eb\u542b\u91cf\u30fbPEG\u4fee\u98fe\u306e\u5f71\u97ff\u300d<\/li>\n<\/ol>\n\n\n\n

                      \u5916\u90e8\u8cc7\u91d1\u7372\u5f97\uff08\u7af6\u4e89\u7684\u8cc7\u91d1\u306e\u307f\u8a18\u8f09\uff09<\/strong><\/h4>\n\n\n\n
                        \n
                      1. \u8fd1\u85e4\u5553\uff08\u4ee3\u8868\uff09\u3001\u91d1\u6ca2\u8cb4\u61b2\u3001\u7167\u559c\u540d\u5b5d\u4e4b\u3001\u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76\uff08C\uff09\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                      2. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u4e0a\u539f\u8a18\u5ff5\u751f\u547d\u79d1\u5b66\u8ca1\u56e3 \u7814\u7a76\u52a9\u6210\u91d1\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                      3. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001AMED \u5275\u85ac\u57fa\u76e4\u63a8\u9032\u7814\u7a76\u4e8b\u696d\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                      4. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76\uff08B)\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                      5. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u4ed6\u3001\u79d1\u7814\u8cbb \u6311\u6226\u7684\u7814\u7a76\uff08\u840c\u82bd\uff09\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                      6. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u30ad\u30e4\u30ce\u30f3\u8ca1\u56e3\u52a9\u6210\u30d7\u30ed\u30b0\u30e9\u30e0\u300c\u65b0\u7523\u696d\u3092\u751f\u3080\u79d1\u5b66\u6280\u8853\u300d\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                      7. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u4ed6\u3001JST A-STEP\u30c8\u30e9\u30a4\u30a2\u30a6\u30c8\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                      8. \u91d1\u6ca2\u8cb4\u61b2\uff08\u5206\u62c5\uff09\u3001\u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76 (B)\uff08\u4ee3\u8868\uff1a\u9ad8\u6a4b\u8449\u5b50\uff09\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                      9. \u91d1\u6ca2\u8cb4\u61b2\uff08\u5206\u62c5\uff09\u3001AMED \u5275\u85ac\u57fa\u76e4\u63a8\u9032\u7814\u7a76\u4e8b\u696d\uff08\u4ee3\u8868\uff1a\u77f3\u7530\u7adc\u5f18\uff09\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                      10. \u7167\u559c\u540d\u5b5d\u4e4b\uff08\u4ee3\u8868\uff09\u3001\u79d1\u7814\u8cbb \u82e5\u624b\u7814\u7a76\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                      11. \u98ef\u5ca1\u771f\u543e\uff08\u4ee3\u8868\uff09\u3001\u7279\u5225\u7814\u7a76\u54e1\u5968\u52b1\u8cbb\uff08DC1\uff09\uff08\u7d99\u7d9a\uff09<\/li>\n<\/ol>\n\n\n\n

                        2022\u5e74<\/mark><\/h2>\n\n\n\n

                        Publications<\/h4>\n\n\n\n
                          \n
                        1. Naoki Yoshihara, Ryota Kimata, Takayuki Terukina, Takanori Kanazawa, Hiromu Kondo*: Novel preparation approach with a 2-step process for spherical particles with high drug loading and controlled size distribution using melt granulation: MALCORE\u00ae. Adv Powder Technol<\/strong><\/em> (IF:4.833), 2022;33<\/strong>:103409. https:\/\/doi.org\/10.1016\/j.apt.2021.103409<\/a><\/li>\n\n\n\n
                        2. Hisako Ibaraki, Naruhiro Hatakeyama, Naoki Arima, Akihiro Takeda, Yasuo Seta, Takanori Kanazawa*: Systemic delivery of siRNA to the colon using peptide modified PEG-PCL polymer micelles for the treatment of ulcerative colitis, Euro J Pharm Biopharm<\/em><\/strong> (IF:5.571), 2022;170<\/strong>:170\u2013178. <\/em>https:\/\/doi.org\/10.1016\/j.ejpb.2021.12.009<\/a><\/li>\n\n\n\n
                        3. Takumi Kurano, Takanori Kanazawa*, Aoi Ooba, Yudai Masuyama, Nao Maruhana, Mayu Yamada, Hisako Ibaraki, Yasuhiro Kosuge, Hiromu Kondo, Toyofumi Suzuki, Nose-to-brain\/spinal cord delivery kinetics of liposomes with different surface properties, J Control Release<\/strong><\/em> (IF:9.776), 2022;344:225-234. https:\/\/doi.org\/10.1016\/j.jconrel.2022.03.017<\/a><\/li>\n\n\n\n
                        4. Yusuke Oe, Shinichi Ogino, Masanori Kobayashi, Hiroyuki Kojima, Takayuki Terukina, Takanori Kanazawa, Hiromu Kondo H*, Testosterone sustained release microspheres for the treatment of fecal incontinence, J Pharm Sci<\/em><\/strong> (IF:3.534), 2022;111:2322\u22122329. https:\/\/doi.org\/10.1016\/j.xphs.2022.03.008<\/a><\/li>\n\n\n\n
                        5. Takayuki Terukina, Yoshiki Uchiyama, Fumiya Kikuma, Saki Fukumitsu, Nana Iwata, Takanori Kanazawa, Hiromu Kondo*: A new approach for characterizing the thixotropic properties of gel formulations as sprayable agents based on rheological analysis. AAPS PharmSci Tech <\/em><\/strong>(IF:3.246), 2022;23<\/strong>:119. https:\/\/doi.org\/10.1208\/s12249-022-02276-y<\/a><\/li>\n\n\n\n
                        6. Hisako Ibaraki, Naruhiro Hatakeyama, Akihiro Takeda, Naoki Arima, Takanori Kanazawa*, Multifunctional peptide carrier-modified polymer micelle accelerates oral siRNA-delivery to the colon and improves gene silencing-mediated therapeutic effects in ulcerative colitis. J Drug Deliv Sci Tech<\/em><\/strong> (IF:3.981), 2022;73<\/strong>:103481. https:\/\/doi.org\/10.1016\/j.jddst.2022.103481<\/a><\/li>\n\n\n\n
                        7. Momoka Yamaguchi*, Takanori Kanazawa*, Sumire Morino, Shingo Iioka, Yuta Watanabe, Naoki Dohi, Kenjirou Higashi, Hiromu Kondo, Tomohisa Ishikawa, Increased tropism of extracellular vesicles derived from palmitic acid-treated hepatocytes to activated hepatic stellate cells. Membranes <\/em><\/strong>(IF:4.562), 2022;12<\/strong>:1023. https:\/\/doi.org\/10.3390\/membranes12101023<\/a><\/li>\n\n\n\n
                        8. Takumi Kurano, Takanori Kanazawa*, Shingo Iioka, Hiromu Kondo, Yasuhiro Kosuge, Toyofumi Suzuki*, Intranasal Administration of N-acetyl-L-cysteine Combined with Cell-Penetrating Peptide-Modified Polymer Nanomicelles as a Potential Therapeutic Approach for Amyotrophic Lateral Sclerosis. Pharmaceutics<\/em><\/strong> 2022;14<\/strong>(12):2590. https:\/\/doi.org\/10.3390\/pharmaceutics14122590<\/a><\/li>\n<\/ol>\n\n\n\n

                          Revi<\/strong>ew artcle\/Book chapter<\/h4>\n\n\n\n
                            \n
                          1. Atsushi Kambayashi, Mika Murano, Shunji Imai, Kenichi Miyata, Katsuji Sugita, Yoshimine Fujii, Masahiro Kinoshita, Akinori Nomura, Takahiro Kimoto, Yoshikazu Miyazaki, Hiroyuki Sakakibara, Sahoe Kakuda, Takuya Tsujimoto, Yuu Fujita, Mayumi Kano, Hideaki Nakamura, Seiichirou Akaogi, Makoto Honda, Makoto Anraku, Noboru Kamada, Kotoe Ohta, Masashi Uchida, Makoto Kataoka, Hiroshi Kikuchi, Shinji Yamashita, Hiromu Kondo, Interspecies differences in gastrointestinal physiology affecting the in vivo<\/em> performance of oral pharmaceutical solid dosage forms. J Drug Deliv Sci Tech<\/em><\/strong> (IF:3.981), 2022;22<\/strong>:102923. https:\/\/doi.org\/10.1016\/j.jddst.2021.102923<\/a> Review article<\/li>\n\n\n\n
                          2. Hisako Ibaraki, Takanori Kanazawa*: In Vivo<\/em> Topical and Systemic Distribution Kinetics of Liposomes with Various Properties for Application to Drug Delivery Systems. Sensors and Materials<\/strong><\/em> (IF:0.759), 2022;34<\/strong>: 987\u20131005. https:\/\/www.myukk.org\/SM2017\/article.php?ss=3673<\/a> Review article<\/li>\n\n\n\n
                          3. Takayuki Yoshida, Hiroyuki Kojima, Kazuhiro Sako, Hiromu Kondo*, Drug delivery to the intestinal lymph by oral formulations. Pharm Dev Technol<\/em><\/strong> (IF:3.133), 2022; https:\/\/doi.org\/10.1080\/10837450.2022.2030353<\/a> Review article<\/li>\n\n\n\n
                          4. Takanori Kanazawa*, Chapter 16: Polymer micelle, Cell-penetrating peptides: Design, Development and Applications (Oba M & Demizu Y, ed.), Wiley-VCH Verlag GmbH & Co.<\/em><\/strong>, 2022;285-313. Book chapter https:\/\/doi.org\/10.1002\/9783527835997.ch16<\/a><\/li>\n\n\n\n
                          5. Takanori Kanazawa*, Chapter 18: Nose-to-brain delivery, Polymer micelles for drug delivery (Kesharwani P & Greish K, ed.), Elsevier<\/em><\/strong>, 2022;479-496 Book chapter https:\/\/doi.org\/10.1016\/B978-0-323-89868-3.00027-6<\/a><\/li>\n<\/ol>\n\n\n\n

                            \u90a6\u6587\u8ad6\u6587\u30fb\u7dcf\u8aac\u30fb\u8457\u66f8<\/h4>\n\n\n\n
                              \n
                            1. \u91d1\u6ca2\u8cb4\u61b2, \u7b2c2\u7ae0 \u9f3b-\u8133\u8f38\u9001\u6a5f\u69cb\u3092\u57fa\u76e4\u3068\u3059\u308b\u4e2d\u67a2\u6a19\u7684DDS\u30ca\u30ce\u30ad\u30e3\u30ea\u30a2\u306e\u958b\u767a, \u4e2d\u5206\u5b50\u5275\u85ac\u306b\u5411\u3051\u305fDDS\u958b\u767a\u306e\u65b0\u5c55\u958b, \u6749\u6797\u5805\u6b21 \u76e3\u4fee, \u30b7\u30fc\u30a8\u30e0\u30b7\u30fc\u51fa\u7248 (2022)<\/li>\n\n\n\n
                            2. \u8328\u6728\u3072\u3055\u5b50, \u91d1\u6ca2\u8cb4\u61b2, \u7b2c9\u7ae0 \u7d30\u80de\u9593\u9699\u3092\u6a19\u7684\u3068\u3057\u305fsiRNA\u7d44\u7e54\u5185\u6d78\u900f\u578bDDS\u306e\u8a2d\u8a08, \u4e2d\u5206\u5b50\u5275\u85ac\u306b\u5411\u3051\u305fDDS\u958b\u767a\u306e\u65b0\u5c55\u958b, \u6749\u6797\u5805\u6b21 \u76e3\u4fee, \u30b7\u30fc\u30a8\u30e0\u30b7\u30fc\u51fa\u7248 (2022)<\/li>\n\n\n\n
                            3. \u8fd1\u85e4\u5553, \u7814\u7a76\u5ba4\u7d39\u4ecb\uff1a\u88fd\u5264\u5b66\u3068\u697d\u3057\u304f\u3001\u9762\u767d\u304f\u4ed8\u304d\u5408\u3063\u3066\u3044\u304d\u305f\u3044, \u85ac\u5264\u5b66, 2022;82(2):94-97.<\/li>\n\n\n\n
                            4. \u7167\u559c\u540d\u5b5d\u4e4b, \u8fd1\u85e4\u5553, \u8cbc\u4ed8\u5264\u306e\u88fd\u5264\u5b66\u7684\u7279\u6027\u3092\u8b58\u5225\u53ef\u80fd\u3068\u3059\u308b\u8a55\u4fa1\u6cd5\u306b\u95a2\u3059\u308b\u691c\u8a0e, \u533b\u5b66\u3068\u85ac\u5b66, 2022;79<\/li>\n<\/ol>\n\n\n\n

                              \u53d7\u8cde<\/h4>\n\n\n\n
                                \n
                              1. \u7530\u4e2d\u60c7\uff08M1\uff09\u3001\u65e5\u672c\u85ac\u5264\u5b66\u4f1a\u6c38\u4e95\u8ca1\u56e3\u5927\u5b66\u9662\u751f\u30b9\u30ab\u30e9\u30b7\u30c3\u30d7\u300c\u30cf\u30a4\u30c9\u30ed\u30b2\u30eb\u5f62\u6210\u5f90\u653e\u6027\u9320\u306e\u30b2\u30eb\u7c98\u5f3e\u6027\u3068\u6eb6\u51fa\u7279\u6027\u3068\u306e\u95a2\u9023\u6027\u300d<\/li>\n\n\n\n
                              2. \u5185\u5c71\u5609\u7a00\uff08M2\uff09\u3001\u65e5\u672c\u85ac\u5264\u5b66\u4f1a\u7b2c37\u5e74\u4f1a\u6700\u512a\u79c0\u767a\u8868\u8005\u8cde\u300c\u6301\u7d9a\u6eb6\u51fa\u6027\u306a\u3089\u3073\u306b\u7c98\u819c\u4ed8\u7740\u6027\u3092\u6709\u3059\u308b\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u30b7\u30fc\u30c8\u88fd\u5264\u306e\u8a2d\u8a08\u3068\u8a55\u4fa1\u300d<\/li>\n\n\n\n
                              3. \u98ef\u5ca1\u771f\u543e\uff08D2\uff09\u3001\u65e5\u672c\u6838\u9178\u533b\u85ac\u5b66\u4f1a\u7b2c7\u56de\u5e74\u4f1a\u5ddd\u539f\u8cde\u300cALS\u30e2\u30c7\u30eb\u30de\u30a6\u30b9\u306b\u304a\u3051\u308bsiRNA\u642d\u8f09Nose-to-Brain\u30df\u30bb\u30eb\u306e\u810a\u9ac4\u5185\u6a19\u7684\u907a\u4f1d\u5b50\u767a\u73fe\u6291\u5236\u52b9\u679c\u3068\u6cbb\u7642\u52b9\u679c\u300d<\/li>\n\n\n\n
                              4. \u5c3e\u718a\u8cb4\u4e4b\uff08\u793e\u4f1a\u4ebaD2\uff09\u3001\u5275\u5264\u30d5\u30a9\u30fc\u30e9\u30e0\u7b2c27\u56de\u82e5\u624b\u7814\u7a76\u4f1a\u6700\u512a\u79c0\u767a\u8868\u8cde\u300cBxPC-3\u62c5\u304c\u3093\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u7d44\u7e54\u6d78\u900f\u6027siRNA\u5185\u5c01\u30ea\u30dd\u30bd\u30fc\u30e0\u306e\u816b\u760d\u5185\u5206\u5e03\u3068\u6297\u816b\u760d\u52b9\u679c\u300d<\/li>\n\n\n\n
                              5. \u98ef\u5ca1\u771f\u543e\uff08D2\uff09\u3001\u5275\u5264\u30d5\u30a9\u30fc\u30e9\u30e0\u7b2c27\u56de\u82e5\u624b\u7814\u7a76\u4f1a\u512a\u79c0\u767a\u8868\u8cde\u300c\u30de\u30a4\u30af\u30ed\u6d41\u4f53\u30c7\u30d0\u30a4\u30b9\u3092\u7528\u3044\u305f\u30d6\u30ed\u30c3\u30af\u30dd\u30ea\u30de\u30fc\u30ca\u30ce\u7c92\u5b50\u306e\u7269\u6027\u304a\u3088\u3073Nose-to-Brain\u5206\u5e03\u52d5\u614b\u306b\u53ca\u307c\u3059\u5206\u5b50\u91cf\u306e\u5f71\u97ff\u300d<\/li>\n<\/ol>\n\n\n\n

                                \u5916\u90e8\u8cc7\u91d1\u7372\u5f97\uff08\u7af6\u4e89\u7684\u8cc7\u91d1\u306e\u307f\u8a18\u8f09\uff09<\/strong><\/h4>\n\n\n\n
                                  \n
                                1. \u8fd1\u85e4\u5553\uff08\u4ee3\u8868\uff09\u3001\u91d1\u6ca2\u8cb4\u61b2\u3001\u7167\u559c\u540d\u5b5d\u4e4b\u3001\u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76\uff08C\uff09\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                                2. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u4ed6\u3001 \u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76 (B) \uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                                3. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001AMED \u5275\u85ac\u7dcf\u5408\u652f\u63f4\u4e8b\u696d\uff08\u5275\u85ac\u30d6\u30fc\u30b9\u30bf\u30fc\uff09\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                                4. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u4ed6\u3001\u5c0f\u91ce\u533b\u5b66\u7814\u7a76\u8ca1\u56e3\u3001\u7814\u7a76\u5968\u52b1\u52a9\u6210\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                5. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u30ad\u30e4\u30ce\u30f3\u8ca1\u56e3\u52a9\u6210\u30d7\u30ed\u30b0\u30e9\u30e0\u300c\u65b0\u7523\u696d\u3092\u751f\u3080\u79d1\u5b66\u6280\u8853\u300d\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                6. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u4ed6\u3001\u79d1\u7814\u8cbb \u6311\u6226\u7684\u7814\u7a76\uff08\u840c\u82bd\uff09\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                7. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u4ed6\u3001JST A-STEP\u30c8\u30e9\u30a4\u30a2\u30a6\u30c8\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                8. \u91d1\u6ca2\u8cb4\u61b2\uff08\u5206\u62c5\uff09\u3001\u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76 (B)\uff08\u4ee3\u8868\uff1a\u9ad8\u6a4b\u8449\u5b50\uff09\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                9. \u91d1\u6ca2\u8cb4\u61b2\uff08\u5206\u62c5\uff09\u3001AMED \u5275\u85ac\u57fa\u76e4\u63a8\u9032\u7814\u7a76\u4e8b\u696d\uff08\u4ee3\u8868\uff1a\u77f3\u7530\u7adc\u5f18\uff09\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                10. \u91d1\u6ca2\u8cb4\u61b2\uff08\u5206\u62c5\uff09\u3001\u6d66\u4e0a\u98df\u54c1\u30fb\u98df\u6587\u5316\u632f\u8208\u8ca1\u56e3 \u7814\u7a76\u52a9\u6210\uff08\u4ee3\u8868\uff1a\u5c71\u53e3\u6843\u751f\uff09\uff08\u65b0\u898f\uff09 <\/li>\n\n\n\n
                                11. \u7167\u559c\u540d\u5b5d\u4e4b\uff08\u4ee3\u8868\uff09\u3001\u79d1\u7814\u8cbb \u82e5\u624b\u7814\u7a76\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                                12. \u98ef\u5ca1\u771f\u543e\uff08\u4ee3\u8868\uff09\u3001\u7279\u5225\u7814\u7a76\u54e1\u5968\u52b1\u8cbb\uff08DC1\uff09\uff08\u65b0\u898f\uff09<\/li>\n<\/ol>\n\n\n\n

                                  <\/p>\n\n\n\n

                                  2021\u5e74<\/mark><\/h2>\n\n\n\n

                                  Publications<\/h4>\n\n\n\n
                                    \n
                                  1. Takayuki Terukina, Taisei Takizawa, Shingo Iioka, Fuya Suzuki, Takanori Kanazawa, Hiromu Kondo*, Characterization of the viscoelasticity of disintegrants by dynamic rheological analysis. Powder Technol<\/strong><\/em> (IF:5.134), 2021;392<\/strong>:150-156. https:\/\/doi.org\/10.1016\/j.powtec.2021.07.009<\/a><\/li>\n\n\n\n
                                  2. Misako Kawai, Hisako Ibaraki, Yuuki Takashima, Takanori Kanazawa*, Hiroaki Okada: Development of a Liquid Crystal Formulation that Can Penetrate the Stratum Corneum for Intradermal Delivery of Small Interfering RNA. Mol Pharm<\/strong><\/em> (IF:4.939), 2021;18<\/strong>(3):1038-1047. doi: 10.1021\/acs.molpharmaceut.0c00997<\/li>\n\n\n\n
                                  3. Hisako Ibaraki, Akihiro Takeda, Naoki Arima, Naruhiro Hatakeyama, Yuuki Takashima, Yasuo Seta, Takanori Kanazawa*: In vivo<\/em> fluorescence imaging of passive inflammation site accumulation of liposomes via intravenous administration focused on their surface charge and PEG modification. Pharmaceutics<\/strong><\/em> (IF:6.321), 2021;13<\/strong>:104. doi: 10.3390\/pharmaceutics13010104<\/li>\n\n\n\n
                                  4. Mitsuyoshi Fukuda, Takanori Kanazawa*, Shingo Iioka, Takayuki Oguma , Ryohei Iwasa, Saki Masuoka, Naoto Suzuki, Yasuhiro Kosuge, Toyofumi Suzuki*, Quantitative analysis of inulin distribution in the brain focused on nose-to-brain route via olfactory epithelium by reverse esophageal cannulation, J Control Release<\/strong><\/em> (IF:9.776), 2021;332<\/strong>:493-501.doi: 10.1016\/j.jconrel.2021.02.024.<\/li>\n\n\n\n
                                  5. Takanori Kanazawa*, Yuki Hoashi, Hisako Ibaraki, Yuuki Takashima, Hiroaki Okada, Electroporation-based ex vivo<\/em> gene delivery into dendritic cells by anionic polymer-coated versatile nuclear localization signal\/pDNA complex, Biol Pharm Bull<\/em><\/strong> (IF:2.233), 2021;44<\/strong>:<\/li>\n\n\n\n
                                  6. Noriyasu Kamei, Susumu Suwabe, Kenji Arime, Hidemi Bando, Kaho Murata, Maika Yamaguchi, Natsuki Yokoyama, Erina Tanaka, Ayaka Hashimoto, Takanori Kanazawa, Yukio Ago, Mariko Takeda-Morishita, Investigation of the transport pathways associated with enhanced brain delivery of peptide drugs by intranasal coadministration with penetratin. Pharmaceutics<\/strong><\/em> (IF:6.321), 2021;13<\/strong>:1745. https:\/\/doi.org\/10.3390\/pharmaceutics13111745<\/li>\n<\/ol>\n\n\n\n

                                    \u548c\u6587\u7dcf\u8aac<\/h4>\n\n\n\n
                                      \n
                                    1. \u8fd1\u85e4\u5553: \u7d4c\u53e3\u653e\u51fa\u5236\u5fa1\u88fd\u5264\u6280\u8853\u306e\u6700\u8fd1\u306e\u52d5\u5411, \u6708\u520a\u30d5\u30a1\u30a4\u30f3\u30b1\u30df\u30ab\u30eb, 2021; 50(1):5-9.<\/li>\n\n\n\n
                                    2. \u91d1\u6ca2\u8cb4\u61b2: \u9f3b-\u8133\u8f38\u9001\u6a5f\u69cb\u3092\u57fa\u76e4\u3068\u3059\u308b\u4e2d\u67a2\u6a19\u7684DDS\u30ca\u30ce\u30ad\u30e3\u30ea\u30a2\u306e\u958b\u767a, \u6708\u520a\u30d5\u30a1\u30a4\u30f3\u30b1\u30df\u30ab\u30eb, 2021;50(6):17-23<\/li>\n\n\n\n
                                    3. \u8328\u6728\u3072\u3055\u5b50\u3001\u91d1\u6ca2\u8cb4\u61b2: \u7d30\u80de\u9593\u9699\u3092\u6a19\u7684\u3068\u3057\u305fsiRNA\u7d44\u7e54\u5185\u6d78\u900f\u578bDDS\u306e\u8a2d\u8a08, \u6708\u520a\u30d5\u30a1\u30a4\u30f3\u30b1\u30df\u30ab\u30eb, 2021;50(6):29-34<\/li>\n\n\n\n
                                    4. \u91d1\u6ca2\u8cb4\u61b2: \u6838\u9178\u533b\u85ac\u306b\u304a\u3051\u308b\u975e\u4fb5\u8972\u7684\u306a\u6295\u4e0e\u30eb\u30fc\u30c8\u3068 DDS, \u6838\u9178\u533b\u85ac\u3000\u672c\u9818\u3092\u767a\u63ee\u3059\u308b\u5275\u85ac\u30e2\u30c0\u30ea\u30c6\u30a3, \u5b9f\u9a13\u533b\u5b66\u5897\u520a\u53f7, 2021;39(17):102-108<\/li>\n<\/ol>\n\n\n\n

                                      \u53d7\u8cde<\/h4>\n\n\n\n
                                        \n
                                      1. \u89d2\u7530\u8ce2\u54c9\uff08B6\uff09\u3001\u65e5\u672c\u85ac\u5264\u5b66\u4f1a\u6c38\u4e95\u8ca1\u56e3\u5b66\u90e8\u5b66\u751f\u4e03\u3064\u661f\u85ac\u5e2b\u5968\u52b1\u8cde\u300c\u30a4\u30c8\u30e9\u30b3\u30ca\u30be\u30fc\u30eb\u306e\u56fa\u4f53\u5206\u6563\u4f53\u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u30b7\u30fc\u30c8\u88fd\u5264\u306e\u8abf\u88fd\u3068\u8a55\u4fa1\u300d<\/li>\n\n\n\n
                                      2. \u7530\u4e2d\u60c7\uff08B4\uff09\u3001\u7b2c67\u56de\u65e5\u672c\u85ac\u5b66\u4f1a\u6771\u6d77\u652f\u90e8\u5927\u4f1a \u5b66\u751f\u512a\u79c0\u767a\u8868\u8cde\u53d7\u8cde\u300c\u30cf\u30a4\u30c9\u30ed\u30b2\u30eb\u5f62\u6210\u5f90\u653e\u9320\u306e\u30b2\u30eb\u7c98\u5f3e\u6027\u3068\u6eb6\u51fa\u6027\u3068\u306e\u95a2\u9023\u6027\u300d<\/li>\n\n\n\n
                                      3. \u91d1\u6ca2\u8cb4\u61b2\u3001\u4ee4\u548c2\u5e74\u5ea6\u5b66\u9577\u8868\u5f70<\/li>\n<\/ol>\n\n\n\n

                                        \u305d\u306e\u4ed6<\/h4>\n\n\n\n
                                          \n
                                        1. \u8fd1\u85e4\u5553: \u3088\u308a\u4f7f\u3044\u3084\u3059\u304f\u3001\u78ba\u304b\u306a\u52b9\u679c\u3092 \u9032\u5316\u3059\u308b\u88fd\u5264\u6280\u8853\u3001\u4fdd\u5065\u540c\u4eba\u793e\u300c\u307f\u3093\u306a\u306e\u5065\u5eb7\u30e9\u30a4\u30d6\u30e9\u30ea\u30fc\u300d\u3001\u6bce\u65e5\u65b0\u805e\u300c\u533b\u7642\u30d7\u30ec\u30df\u30a2\u300d<\/li>\n<\/ol>\n\n\n\n

                                          \u5916\u90e8\u8cc7\u91d1\u7372\u5f97\uff08\u7af6\u4e89\u7684\u8cc7\u91d1\u306e\u307f\u8a18\u8f09\uff09<\/strong><\/p>\n\n\n\n

                                            \n
                                          1. \u8fd1\u85e4\u5553\uff08\u4ee3\u8868\uff09\u3001\u91d1\u6ca2\u8cb4\u61b2\u3001\u7167\u559c\u540d\u5b5d\u4e4b\u3001\u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76\uff08C\uff09\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                          2. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u4ed6\u3001 \u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76 (B) \uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                                          3. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u8fd1\u85e4\u5553\u3001\u7167\u559c\u540d\u5b5d\u4e4b\u3001JST A-STEP\u30c8\u30e9\u30a4\u30a2\u30a6\u30c8\uff08\u7d99\u7d9a\uff09<\/li>\n\n\n\n
                                          4. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u4e2d\u5bcc\u5065\u5eb7\u79d1\u5b66\u8ca1\u56e3 \u7814\u7a76\u52a9\u6210\u91d1\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                          5. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001\u6b66\u7530\u79d1\u5b66\u632f\u8208\u8ca1\u56e3 \u85ac\u5b66\u7cfb\u7814\u7a76\u52a9\u6210\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                          6. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\u3001AMED \u5275\u85ac\u7dcf\u5408\u652f\u63f4\u4e8b\u696d\uff08\u5275\u85ac\u30d6\u30fc\u30b9\u30bf\u30fc\uff09\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                          7. \u7167\u559c\u540d\u5b5d\u4e4b\uff08\u4ee3\u8868\uff09\u3001\u79d1\u7814\u8cbb \u82e5\u624b\u7814\u7a76\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                          8. \u7167\u559c\u540d\u5b5d\u4e4b\uff08\u4ee3\u8868\uff09\u3001\u9759\u5ca1\u770c\u5316\u7ca7\u54c1\u958b\u767a\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u5f37\u5316\u306b\u8cc7\u3059\u308b\u7814\u7a76\uff08\u7d99\u7d9a\uff09<\/li>\n<\/ol>\n\n\n\n

                                            <\/p>\n\n\n\n

                                            2020\u5e74<\/mark><\/h2>\n\n\n\n

                                            Publications<\/h4>\n\n\n\n
                                              \n
                                            1. Kambayashi A, Sako K, Kondo H*, Effects of Diurnal Variation and Food on Gastrointestinal Transit of 111In-Labeled Hydrogel Matrix Extended-Release Tablets and 99mTc-Labeled Pellets in Humans. J. Pharm. Sci.<\/em>, 2020;109(2):1020-1025.<\/li>\n\n\n\n
                                            2. Kambayashi A, Sako K, Kondo H*, Characterization of the buccal and gastric transit of orally disintegrating tablets in humans using gamma scintigraphy. Int. J. Pharm.<\/em>, 2020;576:118937.<\/li>\n\n\n\n
                                            3. Yoshida T, Sako K, Kondo H*, Design of novel tacrolimus formulations with chemically synthesized oils for oral lymphatic delivery. Drug Dev. Ind. Pharm.<\/em>, 2020;46(2):219-226.<\/li>\n\n\n\n
                                            4. Kanazawa T*, Taki H, Okada H, Nose-to-brain drug delivery system with ligand\/cell-penetrating peptide-modified polymeric nano-micelles for intracerebral gliomas, Euro. J. Pharm. Biopharm.<\/em>, 2020;152:85\u201394.<\/li>\n\n\n\n
                                            5. Ibaraki H, Kanazawa T*, Chien WY, Nakaminami H*, Aoki M, Ozawa K, Kaneko H, Takashima Y, Noguchi N, Seta Y, The effects of surface properties of liposomes on their activity against Pseudomonas aeruginosa PAO-1 biofilm, J. Drug Deliv. Sci. Tech.<\/em> 2020;57:101754.<\/li>\n\n\n\n
                                            6. Nango H, Kosuge Y Yoshimura N, Miyagishi H, Kanazawa T, Hashizaki K, Suzuki T, Ishige K, The molecular mechanisms underlying prostaglandin D2-induced neuritogenesis in motor neuron-like NSC-34 cells, Cells<\/em>, 2020;9(4):934.<\/li>\n\n\n\n
                                            7. Suzuki N, Kanazawa T, Takatori K, Suzuki T, Fukami T, Crystal Structure Analysis and Pharmaceutical Properties of Amide Salts Consisting of Paracetamol\/Sulfonic Acids as Solid Forms Prepared by Grinding. Cryst. Growth. Des.<\/em>, 2020;20(2):590-599.<\/li>\n\n\n\n
                                            8. Ibaraki H, Kanazawa T*, Owada M, Iwaya K, Takashima Y, Seta Y, Anti-Metastatic Effects on Melanoma via Intravenous Administration of Anti-NF-\u03baB siRNA Complexed with Functional Peptide-Modified Nano-Micelles, Pharmaceutics<\/em>, 2020;12(1):64.<\/li>\n\n\n\n
                                            9. Salam MT, Kumar A, Hata A, Kondo H, Salam MA, Wahed M, Khan RI, Barman RK, Accelerated Aqueous Solubility and Antibacterial Activity of Cefuroxime Axetil Using Microcrystalline Cellulose as Carrier, Pharmacology & Pharmacy<\/em>, 2020;11:159-173.<\/li>\n\n\n\n
                                            10. Suzuki T, Kurano T, Kanazawa T, Suzuki N, Establishment of a Novel Method to Evaluate Water Permeation Rates by Combining the Dynamic Contact Angle and Thermographic Approach: Signicance of Disintegration Properties of Orally Disintegrating Tablets, Yakugaku Zasshi<\/em>, 2020;140(8):1071-1080.<\/li>\n\n\n\n
                                            11. Atsushi Kambayashi, Kazuhiro Sako, Hiromu Kondo*: Scintigraphic evaluation of the in vivo performance of dry-coated delayed release tablets in humans, Euro. J. Pharm. Biopharm.<\/em>, 2020;152:116\u2013122<\/li>\n<\/ol>\n\n\n\n

                                              <\/p>\n\n\n\n

                                              \u548c\u6587\u7dcf\u8aac<\/h4>\n\n\n\n
                                                \n
                                              1. \u9234\u6728\u76f4\u4eba, \u91d1\u6ca2\u8cb4\u61b2, \u9234\u6728\u8c4a\u53f2: Nose-to-Brain\u30c7\u30ea\u30d0\u30ea\u30fc\u3092\u6307\u5411\u3057\u305f\u7d4c\u9f3b\u6295\u4e0e\u88fd\u5264\u306e\u8a2d\u8a08, PHARM TECH JAPAN<\/em><\/i>, 2020;36(7):128-132<\/li>\n\n\n\n
                                              2. \u9234\u6728\u8c4a\u53f2, \u9234\u6728\u76f4\u4eba, \u91d1\u6ca2\u8cb4\u61b2: \u9f3b\u304b\u3089\u8133\u3078\u306e\u85ac\u7269\u9001\u9054\u306b\u304a\u3051\u308b\u8f38\u9001\u6a5f\u69cb\u3068\u30ca\u30ce\u30b7\u30b9\u30c6\u30e0\u306e\u5f79\u5272, \u30aa\u30ec\u30aa\u30b5\u30a4\u30a8\u30f3\u30b9, 2020;20(2):61-69<\/li>\n\n\n\n
                                              3. \u9234\u6728\u76f4\u4eba, \u91d1\u6ca2\u8cb4\u61b2, \u9234\u6728\u8c4a\u53f2: \u7d4c\u9f3b\u6295\u4e0e, \u9023\u8f09 DDS\u306e\u300c\u3061\u3087\u3063\u3068\u3057\u305f\u300d\u6280\u8853\u30fb\u77e5\u8b58 \u7b2c5\u56de, Drug Delivery System<\/em>, 2020;35(1):76-80<\/li>\n\n\n\n
                                              4. \u8fd1\u85e4\u5553: \u30ca\u30ce\u30d5\u30a1\u30a4\u30d0\u30fc\u3092\u5229\u7528\u3057\u305f\u85ac\u7269\u6cbb\u7642\u306b\u3064\u306a\u304c\u308b\u653e\u51fa\u5236\u5fa1\u88fd\u5264\u306e\u958b\u767a\u3092\u76ee\u6307\u3057\u3066, PHARM TECH JAPAN<\/em>, 2020;36(17):133-138<\/li>\n\n\n\n
                                              5. \u91d1\u6ca2\u8cb4\u61b2: \u4e2d\u67a2\u795e\u7d4c\u7cfb\u9818\u57df\u3092\u6a19\u7684\u3068\u3059\u308b\u85ac\u7269\u30fb\u6838\u9178\u533b\u85ac\u306eNose-to-Brain\u30c7\u30ea\u30d0\u30ea\u30fc\u306b\u95a2\u3059\u308b\u7814\u7a76:\u7b2c12\u56de \u65e5\u672cDDS\u5b66\u4f1a\u5968\u52b1\u8cde\uff08\u81e8\u5e8a\uff09\u306b\u3088\u305b\u3066, Drug Delivery System<\/em>, 2020;35(5):434-441<\/li>\n<\/ol>\n\n\n\n

                                                \u53d7\u8cde<\/h4>\n\n\n\n
                                                  \n
                                                1. \u91d1\u6ca2\u8cb4\u61b2, \u65e5\u672cDDS\u5b66\u4f1a 2020\u5e74\u5ea6\uff08\u7b2c12\u56de\uff09\u5968\u52b1\u8cde \u300c\u4e2d\u67a2\u795e\u7d4c\u7cfb\u9818\u57df\u3092\u6a19\u7684\u3068\u3059\u308b\u85ac\u7269\u30fb\u6838\u9178\u533b\u85ac\u306eNose-to-Brain\u30c7\u30ea\u30d0\u30ea\u30fc\u306b\u95a2\u3059\u308b\u7814\u7a76\u300d<\/li>\n<\/ol>\n\n\n\n

                                                  \u5916\u90e8\u8cc7\u91d1\u7372\u5f97\uff08\u7af6\u4e89\u7684\u8cc7\u91d1\u306e\u307f\u8a18\u8f09\uff09<\/strong><\/p>\n\n\n\n

                                                    \n
                                                  1. \u8fd1\u85e4\u5553\uff08\u4ee3\u8868\uff09, 2020\u5e74\u5ea6 \u85e4\u679d\u5e02\u5730\u57df\u653f\u7b56\u7814\u7a76\u30fb\u5275\u9020\u4e8b\u696d\u52a9\u6210\u91d1\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                                  2. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09, \u79d1\u7814\u8cbb \u57fa\u76e4\u7814\u7a76 (B) \uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                                  3. \u91d1\u6ca2\u8cb4\u61b2\uff08\u4ee3\u8868\uff09\uff0c\u8fd1\u85e4\u5553\uff0c\u7167\u559c\u540d\u5b5d\u4e4b\uff0cJST A-STEP\u30c8\u30e9\u30a4\u30a2\u30a6\u30c8\uff08\u65b0\u898f\uff09<\/li>\n\n\n\n
                                                  4. \u7167\u559c\u540d\u5b5d\u4e4b\uff08\u4ee3\u8868\uff09, \u9759\u5ca1\u770c\u5316\u7ca7\u54c1\u958b\u767a\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u5f37\u5316\u306b\u8cc7\u3059\u308b\u7814\u7a76\uff08\u65b0\u898f\uff09<\/li>\n<\/ol>\n\n\n\n

                                                    <\/p>\n","protected":false},"excerpt":{"rendered":"

                                                    2026\u5e74 2025\u5e74 Publications \u53d7\u8cde \u5916\u90e8\u8cc7\u91d1\u7372\u5f97\uff08\u7af6\u4e89\u7684\u8cc7\u91d1\u306e\u307f\u8a18\u8f09\uff09 2024\u5e74 Publications \u53d7\u8cde \u5916\u90e8\u8cc7\u91d1\u7372\u5f97\uff08\u7af6\u4e89\u7684\u8cc7\u91d1\u306e\u307f\u8a18\u8f09\uff09 2023\u5e74 Publications Revie … <\/p>\n

                                                    “4. \u7814\u7a76\u696d\u7e3e” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":2,"featured_media":0,"parent":169,"menu_order":4,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-156","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng\/index.php?rest_route=\/wp\/v2\/pages\/156","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=156"}],"version-history":[{"count":144,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng\/index.php?rest_route=\/wp\/v2\/pages\/156\/revisions"}],"predecessor-version":[{"id":1317,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng\/index.php?rest_route=\/wp\/v2\/pages\/156\/revisions\/1317"}],"up":[{"embeddable":true,"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng\/index.php?rest_route=\/wp\/v2\/pages\/169"}],"wp:attachment":[{"href":"https:\/\/w3pharm.u-shizuoka-ken.ac.jp\/pharmeng\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=156"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}