1.自転公転型ミキサーを用いた粉体操作
1-1.混和
1-2.粒子複合化
1-3.造粒
【参考文献】
Takashi Eda, Yasunori Miyazaki, Tomonobu Uchino, Yoshiyuki Kagawa: Small-Scale Spherical Granulation Using a Planetary Centrifugal Mixer..
Chem. Pharm. Bull., 68(3), 251-257 (2020).
Yasunori Miyazaki, Ayaka Tsuboi, Saori Maruyama, Hiroaki Aoshima, Tomonobu Uchino, Yoshiyuki Kagawa: Evaluation of Dantrolene Granules Extemporaneously Reformulated from Capsules in a Pharmacy..
Chem. Pharm. Bull., 68(10), 989-995 (2020).
Yasunori Miyazaki, Tomonobu Uchino, Yoshiyuki Kagawa: Compounding of low-dose pharmaceutical powders using a planetary centrifugal mixer.
Journal of Drug Delivery Science and Technology. 52: 103-109 (2019).
2.透湿性保護軟膏の開発と評価
2-1.機能性評価
2-2.臨床評価
3.ペプチド性医薬品の経口投与デバイスの開発
3-1.ポリイオンコンプレックスマトリックスの利用
3-2.マルチプルユニット型製剤の開発
【参考文献】
Yasunori Miyazaki, Midori Mieno, Tomonobu Uchino, Yoshiyuki Kagawa:
Influence of molecular weight and structure on diffusion rates and mechanisms of dextran polyelectrolyte complexes
Carbohydrate Polymers, 162, 42-48 (2017)
