静岡県立大学臨床薬剤学分野

論文

2019

*Tomonobu Uchino, Sayaka Kato, Ichiro Hatta, Yasunori Miyazaki, Tomonori Suzuki, Kohta Sasaki, Yoshiyuki Kagawa: Study on the drug permeation mechanism from flurbiprofen-loaded glyceryl monooleyl ether-based lyotropic liquid crystalline nanoparticles across the skin: synchrotron X-ray diffraction and confocal laser scanning microscopy study..

Int J Pharm. 555: 259-269 (2019).

 

*Yasunori Miyazaki, Tomonobu Uchino, Yoshiyuki Kagawa: Compounding of low-dose pharmaceutical powders using a planetary centrifugal mixer.

Journal of Drug Delivery Science and Technology. 52: 103-109 (2019).

 

2018

*Tomoka Fushimi, Tomonobu Uchino, Yasunori Miyazaki, Ichiro Hatta, Miyuki, Asano, Hiyori Fujino, Rie Suzuki, Shun Fujimori, Daichi Kamiya, Yoshiyuki Kagawa: Development of phospholipid nanoparticles encapsulating 3-O-cetylascorbic acid and tocopherol acetate (TA-Cassome) for improving their skin accumulation.

Int J Pharm. 548(1): 192-205 (2018).

 

*Tomonori Suzuki, Tomonobu Uchino, Ichiro Hatta, Yasunori Miyazaki, Sayaka Kato, Kohta Sasaki, Yoshiyuki Kagawa: Evaluation of the molecular lipid organization in millimeter-sized stratumcorneum by synchrotron X-ray diffraction.

Skin Res Technol. 24(4): 621-629 (2018).

 

*Yoshiaki Yamamoto, Naotaka Usui, Takuji Nishida, Miho Mori, Yukitoshi Takahashi, Katsumi Imai, Yoshiyuki Kagawa, Yushi Inoue: Influence of Renal Function on Pharmacokinetics of Antiepileptic Drugs Metabolized by CYP3A4 in a Patient With Renal Impairment..

Ther Drug Monit. 40(1): 144-147(2018).

 

*Motoaki Ishikawa, Michiyasu Kawai, Toshio Maeda, Yoshiyuki Kagawa: Prediction of neutrophil reduction using plasma paclitaxel concentration after administration in patients with uterine, ovarian, or cervical cancers
in an outpatient clinic.

Cancer Chemother Pharmacol. 81(2):399-411 (2018)

2017

*Yoshiaki Yamamoto, Naotaka Usui, Takuji Nishida, Yukitoshi Takahashi, Katsumi Imai, Yoshiyuki Kagawa, Yushi Inoue: Therapeutic Drug Monitoring for Perampanel in Japanese Epilepsy Patients: Influence of Concomitant Antiepileptic Drugs.

Ther Drug Monit. 39(4):446-449 (2017)

 

*Masaki Tashiro, Takafumi Naito, Yoshiyuki Kagawa, Junichi Kawakami: Influence of cytochrome P450 genotype on the plasma disposition of prochlorperazine metabolites and their relationships with clinical responses in cancer patients.

Ann Clin Biochem. Jan 1:4563217731432. doi: 10.1177/0004563217731432 (2017)

 

*Yoshiaki Yamamoto, Naotaka Usui, Takuji Nishida, Miho Mori, Yukitoshi Takahashi, Katsumi Imai, Yoshiyuki Kagawa, Yushi Inoue:Influence of renal function on pharmacokinetics of antiepileptic drugs metabolized by CYP3A4 in a patient with renal impairment.

Ther Drug Monit. Oct 31. doi: 10.1097/FTD.0000000000000461. (2017)

 

*Yasunori Miyazaki, Midori Mieno, Tomonobu Uchino, Yoshiyuki Kagawa:
Influence of molecular weight and structure on diffusion rates and mechanisms of dextran polyelectrolyte complexes

Carbohydrate Polymers, 162, 42?48 (2017)

 

*Tomonobu Uchino, Ichiro Hatta, Yasunori Miyazaki, Tomoya Onai, Takuto Yamazaki, Fuyoko Sugiura, Yoshiyuki Kagawa: Modulation mechanism of the stratum corneum structure during permeation of surfactant-based rigid and elastic vesicles.

Int J Pharm., 521, 222-231 (2017)

 

*Tomonobu Uchino, Yasunori Miyazaki, Takuto Yamazaki, Yoshiyuki Kagawa:Immunogenicity of protein aggregates of a monoclonal antibody generated by forced shaking stress with siliconized and nonsiliconized syringes in BALB/c mice.

J Pharm Pharmacol., 69, 1341-1351 (2017)

 

*内野智信、宮嵜靖則、藤井亜子、賀川義之:
トコフェリルリン酸封入リン脂質ナノ粒子のキャラクタリゼーション及び皮膚浸透性評価

YAKUGAKU ZASSHI, 137, 979-986 (2017)

 

 

 

2016

*Yoshiaki Yamamoto, Kiyohito Terada, Yukitoshi Takahashi, Katsumi Imai, Yoshiyuki Kagawa, Yushi Inoue: Influence of antiepileptic drugs on serum lipid levels in adult epilepsy patients.

Epilepsy Res., 127, 101-106 (2016)

 

*Kazuki Ide, Hiroshi Yamada, Yohei Kawasaki, Marika Noguchi, Mamoru Kitagawa, Tsuyoshi Chiba, Yoshiyuki Kagawa, Keizo Umegaki:: Reporting of adverse events related to dietary supplements to a public health center by medical staff: a survey of clinics and pharmacies.

Ther Clin Risk Manag., 12, 1403-10 (2016)

 

*Yasunori Miyazaki, Kozo Takayama, Tomonobu Uchino, Yoshiyuki Kagawa:
Application of Response Surface Methodology to Estimate the Design Space of Pharmaceutical Diluents for Dispensing Powdered Formulations.

Chem. Pharm. Bull., 64, 1698?1706 (2016)

2015

*Yoshiaki Yamamoto, Yukitoshi Takahashi, Katsumi Imai, Hiroko Ikeda, Masaaki Takahashi, Masahiko Nakai, Yushi Inoue, Yoshiyuki Kagawa: Influence of uridine diphosphate glucuronosyltransferase inducers and inhibitors on the plasma lamotrigine concentration in pediatric patients with refractory epilepsy.

Drug Metab Pharmacokinet., 30(3), 214-220 (2015)

 

*Takafumi Naito, Yasuaki Mino, Yuki Aoki, Kumi Hirano, Kumiko Shimoyama, Noriyoshi Ogawa, Yoshiyuki Kagawa, Junichi Kawakami: I ABCB1 genetic variant and its associated tacrolimus pharmacokinetics affect renal function in patients with rheumatoid arthritis.

Clin Chim Acta., 445, 79-84 (2015)

 

*Mikiko Tsukimoto, Rikiya Ohashi, Nao Torimoto, Yoko Togo1, Takashi Suzuki, Toshio Maeda, Yoshiyuki Kagawa: Effects of the inhibition of intestinal P-glycoprotein on aliskiren pharmacokinetics in cynomolgus monkeys.

Biopharm Drug Dispos., 36(1), 15-33 (2015)

 

*Yoshiaki Yamamoto, Yukitoshi Takahashi, Katsumi Imai, Kou Miyakawa, Hiroko Ikeda, Yuki Ueda, Tokito Yamaguchi, Hirosato Nasu, Hideyuki Ohtani, Hideo Shigematsu, Yoshiyuki Kagawa, Yushi Inoue: Individualized phenytoin therapy for pediatric Japanese epilepsy patients based on CYP2C9 and CYP2C19 genotypes.

Ther Drug Monit., 37(2), 229-235 (2015)

 

*Yoshiaki Yamamoto, Yukitoshi Takahashi, Katsumi Imai, Nobuyuki Mishima, Yoshiyuki Kagawa, Yushi Inoue: Changing incidence of hyperammonemia in Japan from 2006 to 2013: expansion of new antiepileptic drugs reduces the risk of hyperammonemia.

Eur J Clin Pharmacol., 71(12), 1517-1524 (2015)

 

*Naohito Ide, Kasumi Arisawa, Kanami Ogura, Yoshiyuki Kagawa, Toshio Maeda: Age-Dependent Onset of Insulin Resistance in Insulin-Resistant Mice.

Biol Pharm Bull., 38(12), 1925-1934 (2015)

 

*Yasunori Miyazaki, Kaoru Miyawaki, Tomonobu Uchino, Yoshiyuki Kagawa:
Dry Powder Coating using Planetary Centrifugal Mixer

J. Pharm. Pharm. Sci. 18(3), 460 - 473 (2015)

 

*Tomonobu Uchino, Akiko Murata, Yasunori Miyazaki, Toshihiko Oka, Yoshiyuki Kagawa: Glyceryl Monooleyl Ether-Based Liquid Crystalline Nanoparticles as a Transdermal Delivery System of Flurbiprofen:Characterization and in Vitro Transport.

Chem. Pharm. Bull., 63(5), 54?57 (2015)

 

*Tomonobu Uchino, Yasunori Miyazaki, Tomoyo Ohkawa, Takuto Yamazaki, Yoshitsugu Yanagihar, Takayuki Yoshimori, Mamoru Komatsu, Hiroshi Suzuki, Yoshiyuki Kagawa: Reconstitution of L-Asparaginase in Siliconized Syringes with Shaking and Headspace Air Induces Protein Aggregation.

Chem. Pharm. Bull., 63(10), 770?779 (2015)

2013〜2014

*Yoshiaki Yamamoto, Yukitoshi Takahashi, Katsumi Imai, Masaaki Takahashi, Masahiko Nakai, Yushi Inoue, Yoshiyuki Kagawa: Impact of cytochrome P450 inducers with or without inhibitors on the serum clobazam level in patients with antiepileptic polypharmacy.

Eur. J. Clin. Pharmacol., 70(10), 1203-10 (2014)

 

 

*Yoshiaki Yamamoto, Yukitoshi Takahashi, Katsumi Imai, Yukiko Mogami, Kazumi Matsuda, Masahiko Nakai, Yoshiyuki Kagawa, Yushi Inoue: Interaction between sulthiame and clobazam: Sulthiame inhibits the metabolism of clobazam, possibly via an action on CYP2C19.

Epilepsy Behav., 34, 124-6 (2014)

 

 

*Yasunori Miyazaki, Kaoru Miyawaki, Tomonobu Uchino, Yoshiyuki Kagawa: A novel blending method for dispensing powdered medicine.

Chem. Pharm. Bull., 62(1), 54-57 (2014)

 

 

*Yasunori Miyazaki, Kaoru Miyawaki, Tomonobu Uchino, Yoshiyuki Kagawa:
Assessment of Blending Ratio of Powdered Medicine Mixtures by Image Analysis.

Chem. Pharm. Bull., 62(4), 322-327 (2014)

 

 

*Yasunori Miyazaki, Tomonobu Uchino, Yoshiyuki Kagawa:
Evaluation of Degree of Blending Colored Diluents Using Color Difference Signal Method.

Chem. Pharm. Bull., 62(5), 488-490 (2014)

 

 

*Yasunori Miyazaki, Tomonobu Uchino, Yoshiyuki Kagawa: Blending powdered antineoplastic medicine in disposable ointment container.

Yakugaku Zasshi, 134, 665-70 (2014)

 

 

*Ichie Suzuki, Yasunori Miyazaki, Tomonobu Uchino, Yoshiyuki Kagawa: Influence of locally applied heat on the performance of transdermal diclofenac sodium plasters.

Int. J. Pharm. Pharm. Sci., 6(10), 167-170 (2014)

 

 

*Yukiko Katagiri, Yasunori Miyazaki, Tomonobu Uchino, Yoshiyuki Kagawa:
Preparation of goreisan suppository and pharmacokinetics of trans-cinnamic acid after administration to rabbits.

Biol. Pharm. Bull., 37(11) , 1736-1741 (2014)

 

 

*Tomonobu Uchino, Fons Lefeber, Gert Gooris, Joke Bouwstra:
Characterization and skin permeation of ketoprofen-loaded vesicular systems.

Eur. J. Pharm. Biopharm., 86, 156-66 (2014)

 

 

*Tomonobu Uchino, Yuiko Matsumoto, Akiko Murata, Toshihiko Oka, Yasunori Miyazakia, Yoshiyuki Kagawa:
Transdermal delivery of flurbiprofen from surfactant-based vesicles: Particle characterization and the effect of water on in vitro transport.

Int. J. Pharm., 464, 75-84 (2014)

 

 

*Tsuneyoshi Suzuki, Tomonobu Uchino, Yasunori Miyazaki, Yoshiyuki Kagawa:
The effect of storage time onthe release profile of dexamethasone dipropionate from admixtures of steroid and heparinoid ointments.

Die PHARMAZIE, 69(2), 104-108 (2014)

 

 

* 宮嵜靖則、宮脇薫、内野智信、賀川義之:
デジタル画像処理による散剤の混和度の評価

薬剤学, 印刷中

 

 

*Yoshiyuki Kagawa, Toshio Maeda, Yasuhiro Kato, Iori Ueda, Tomoko Kudo, Naoe Watanabe, MidoriKimura, Sato Minami, Tatsuichiro Sakamoto, Hiroshi Yamada, Masakazu Takagi: Influence of the slowinfusion of a soybean oil emulsion on plasma cytokines and ex vivo T cell proliferation after anesophagectomy.

J. Parenter. Enteral Nutr.2013; 37(1): 123-8.

 

 

* YoshiakiYamamoto, Yukitoshi Takahashi, Katsumi Imai, Nobuyuki Mishima, Rei Yazawa, Kazuyuki Inoue,Kunihiko Itoh, Yoshiyuki Kagawa, Yushi Inoue: Risk factors for hyperammonemia in pediatric patients withepilepsy.

Epilepsia.2013; 54(6): 983-9.

 

 

*Yoshiaki Yamamoto, Yukitoshi Takahashi, Katusmi Imai, Kou Miyakawa, Shigeko Nishimura, Risa Kasai,Hiroko Ikeda, Rumiko Takayama,Yukiko Mogami, Tokito Yamaguchi, Kiyohito Terada, Kazumi Matsuda,YushiInoue, Yoshiyuki Kagawa;
Influence of CYP2C19 polymorphism and concomitant antiepileptic drugs onserum clobazam and N-desmethyl clobazam concentrations in patients with epilepsy.

Ther Drug Monit.2013; Jun; 35(3): 305-12.

 

 

* Toshio Maeda, Ichiro Noge, Yoshiyuki Kagawa:
Infiltration of M1 macrophages into adipose tissue of ddY-H mice preceding spontaneous appearances of insulin resistance.

Biol Pharm Bull.2013;36(5): 825-32.

 

 

* Hikaru Satoh, Naohito Ide, Yoshiyuki Kagawa, Toshio Maeda:
Hepatic steatosis with relation to increasedexpression of peroxisome proliferator-activated receptor-γ in insulin resistant mice.

Biol Pharm Bull.2013; 36(4): 616-23.

 

 

* Tomoyo Ohkawa, Tomonobu Uchino, Daisuke Sasakura, Yasunori Miyazaki, Yoshiyuki Kagawa:
Particlecondition change in emulsion admixture evaluated by in situ flow particle imaging analysis.

Chem Pharm Bull. 2013; 61(3): 333-9.

 

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2011〜2012

* Yoshiaki Yamamoto, Yukitoshi Takahashia, Eri Suzuki, Nobuyuki Mishima, Kazuyuki Inoue, Kunihiko Itoh,Yoshiyuki Kagawa, Yushi Inoue:
Risk factors for hyperammonemia associated with valproic acid therapy inadult epilepsy patients.

Epilepsy Res, 101(3), 202-9, (2012)

 

 

* Yoshiaki Yamamoto, Yushi Inoue, Kazumi Matsuda, Yukitoshi Takahashi, Yoshiyuki Kagawa:
Influence ofConcomitant Antiepileptic Drugs on Plasma Lamotrigine Concentration in Adult Japanese EpilepsyPatients.

Biol Pharm Bull, 35 (4), 487-93, (2012)

 

 

* Takafumi Naito, Masaki Tashiro, Keisuke Yamamoto, Kazunori Ohnishi, Yoshiyuki Kagawa, JunichiKawakami:
* Yoshiaki Yamamoto, Yukitoshi Takahashia, Eri Suzuki, Nobuyuki Mishima, Kazuyuki Inoue, Kunihiko Itoh,Yoshiyuki Kagawa, Yushi Inoue:
Risk factors for hyperammonemia associated with valproic acid therapy inadult epilepsy patients.

Epilepsy Res, 101(3), 202-9, (2012)

 

 

* Yoshiaki Yamamoto, Yushi Inoue, Kazumi Matsuda, Yukitoshi Takahashi, Yoshiyuki Kagawa:
Influence ofConcomitant Antiepileptic Drugs on Plasma Lamotrigine Concentration in Adult Japanese EpilepsyPatients.

Biol Pharm Bull, 35 (4), 487-93, (2012)

 

 

* Takafumi Naito, Masaki Tashiro, Keisuke Yamamoto, Kazunori Ohnishi, Yoshiyuki Kagawa, JunichiKawakami:
Impact of cachexia on pharmacokinetic disposition of and clinical responses to oxycodone incancer patients.

Eur J Clin Pharmacol.68(10):1411-8, (2012)

 

 

* Masaki Tashiro, Takafumi Naito, Yoshiyuki Kagawa, Junichi Kawakami:
Simultaneous determination ofprochlorperazine and its metabolites in human plasma using isocratic liquid chromatography tandem massspectrometry.

Biomed Chromatogr,26(6): 754-60, (2012)

 

 

* Tsuneyoshi Suzuki, Tomonobu Uchino, Yasunori Miyazaki, and Yoshiyuki Kagawa:
Release profiles of dexamethasone dipropionate from admixtures of steroid and heparinoid ointmentsprepared by different mixing methods.

Chem. Pharm. Bull., 60(2), 260-266 (2012)

 

 

* Haruhito Tsutsui, Toshiki Mochizuki, Toshio Maeda, Ichiro Noge, Yutaka Kitagawa, Jun Zhe Min,Kenichiro Todoroki, Koichi Inoue, Toshimasa Toyo’oka:
Simultaneous determination of DL-lactic acid and DL-3-hydroxybutyric acid enantiomers in saliva of diabetes mellitus patients by high-throughput LC-ESI-MS/MS.

Anal. Bioanal. Chem.404, 1925-1934 (2012)

 

 

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* Yasuaki Mino, Takafumi Naito, Atsushi Otsuka, Tatsuya Takayama, Seiichiro Ozono, Yoshiyuki Kagawa,Junichi Kawakami J:
Cyclosporine alters correlation between free and total mycophenolic acid in kidneytransplant recipients in the initial phase.

J Clin Pharm Ther., Apr; 36 (2), 217-24 (2011)

 

 

* Takafumi Naito, Yoshiaki Takashina, Keisuke Yamamoto, Masaki Tashiro, Kazunori Ohnishi, YoshiyukiKagawa, Junichi Kawakami:
CYP3A5*3 Affects Plasma Disposition of Noroxycodone and Dose Escalation inCancer Patients Receiving Oxycodone.

J Clin Pharmacol., 51 (11), 1529-38 (2011)

 

 

* Tomonobu Uchino, Fons Lefeber, Gert Gooris, Joke Bouwstra:
Physicochemical characterization of drug-loaded rigid and elastic vesicles.

Int J Pharm. 412, 142-147 (2011)

 

 

* Haruhito Tsutsui , Toshio Maeda , Jun Zhe Min , Shinsuke Inagaki , Tatsuya Higashi ,Yoshiyuki Kagawa , Toshimasa Toyo'oka:
Biomarker discovery in biological specimens (plasma, hair, liver and kidney)of diabetic mice based upon metabolite profiling using ultra-performance liquid chromatography withelectrospray ionization time-of-flight mass spectrometry.

Clinica Chimica Acta, 412 (11), 861-872 (2011)

 

 

* Noriyuki Yamamoto, Akira Yoshida, Yuko Taki, Satomi Onoue, Yoshiyuki Kagawa, Shizuo Yamada:
Up-regulation of nicotinic and muscarinic receptor mRNA in rat bladder by repeated administration ofnicotine in relation to the pharmacokinetics.

Life Sciences, 89, 343-348 (2011)

 

 

* Shingen Misaka, Souhei Kurosawa, Shinya Uchida, Akira Yoshida, Yoshihisa Kato, Yoshiyuki Kagawa,Shizuo Yamada:
Evaluation of the pharmacokinetic interaction of midazolam with ursodeoxycholic acid,ketoconazole and dexamethasone by brain benzodiazepine receptor occupancy.

J Pharm Pharmacol., 63(1), 58-64 (2011)

 

 

* 鈴木一衛、宮嵜靖則、内野智信、賀川義之:
医療用医薬品と一般用医薬品のブチルスコポラミン臭化物の溶出挙動の比較

薬学雑誌、131、1645-1651 (2011)

 

 

* 内野智信、柳原良次、鈴木洋史:
ラマン分光法による混合後の注射剤成分の非破壊濃度測定

医療薬学、37、599-606 (2011)

 

 

* 山本吉章、家田直幸、三島信行、松田一己、高橋幸利、賀川義之: 
小児てんかん患者に対するトピラマートの治療継続率と安全性の検討;成人を対照とした後ろ向きコホート研究

医療薬学、37(7)、411-418 (2011)

 

 

* 山本吉章、高橋幸利、西村成子、幾見泰洋、三島信行、賀川義之: 
Cytochrome P450 2C9 (CYP2C9) 及び Cytochrome P450 2C19 (CYP2C19) のSingle Nuceotide Polymorphism (SNP) 迅速測定法の開発と小児てんかん患者への臨床応用

YAKUGAKU ZASSHI、131(5)、809-815 (2011)

 

 

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2009〜2010

* Hideki Mizutani, Yusuke Hiraku, Saeko Tada-Oikawa, Mariko Murata, Kenji Ikemura, Takuya Iwamoto,Yoshiyuki Kagawa, Masahiro Okuda and Shosuke Kawanishi:
Romidepsin (FK228), a potent histonedeacetylase inhibitor, induces apoptosis through the generation of hydrogen peroxide.

Cancer Sci,101(10), 2214-2219 (2010)

 

 

* Yoshihiko Ito, Taketsugu Harada, Kasumi Fushimi, Yoshiyuki Kagawa, Hidenobu Oka, Hiroshi Nakazawa,Reiko Homma, Yoshihisa Kato, Shizuo Yamada:
Pharmacokinetic and Pharmacodynamic Analysis ofAcetylcholinesterase Inhibition by Distigmine Bromide in Rats.

Drug Metab Pharmacokinet,25(3), 254-261 (2010)

 

 

* Haruhito Tsutsui, Toshio Maeda, Toshimasa Toyo’oka, Jun Zhe Min, Shinsuke Inagaki, Tatsuya Higashi,Yoshiyuki Kagawa:
Practical Analytical Approach for the Identification of Biomarker Candidates inPrediabetic State Based upon Metabonomic Study by Ultraperformance Liquid Chromatography Coupled toElectrospray Ionization Time-of-Flight Mass Spectrometry.

J Proteome Res., 9(8), 3912-22 (2010)

 

 

* Ichiro Noge, Yoshiyuki Kagawa, Toshio Maeda:
A New Diabetic Mouse Model Derived from the ddY Strain.

Biol Pharm Bull.,33(6), 988-92 (2010).

 

 

* Yasuhiro Katoh, Shinya Uchida, Masayoshi Kawai, Noriyoshi Takei, Norio Mori, Junichi Kawakami,Yoshiyuki Kagawa, Shizuo Yamada, Noriyuki Namiki, Hisakuni Hashimoto:
Effects of Cigarette Smoking andCytochrome P450 2D6 Genotype on Fluvoxamine Concentration in Plasma of Japanese Patients.

Biol Pharm Bull., 33(2), 285-8 (2010)

 

 

* Yasuaki Mino, Takafumi Naito, Atsushi Otsuka, Seiichiro Ozono, Yoshiyuki Kagawa, Junichi Kawakami :
.Inosine monophosphate dehydrogenase activity depends on plasma concentrations of mycophenolic acidand its glucuronides in kidney transplant recipients.

Clin Chim Acta, 409(1-2):56-61. 2009.

 

 

* Yoshiaki Takashina, Takafumi Naito, Yasuaki Mino, Yoshiyuki Kagawa, Junichi Kawakami :
Validated LCcoupled to ESI-MS/MS analysis for fentanyl in human plasma and UV analysis in applied reservoirtransdermal patches using a simple and rapid procedure.

J Clin Pharm Ther.34(5):523-9, 2009.

 

 

* Takafumi Naito, Yasuaki Mino, Atsushi Otsuka, Tomomi Ushiyama, Toshiki Ito, Seiichiro Ozono,Yoshiyuki Kagawa, Junichi Kawakami. :
Impact of calcineurin inhibitors on urinary excretion ofmycophenolic Acid and its glucuronide in kidney transplant recipients.

J Clin Pharmacol,49(6), 710-8, 2009.

 

 

* Takashi Okura T, Yuki Morita, Yoshihiko Ito, Yoshiyuki Kagawa, Shizuo Yamada
:Effects of quinidine onantinociception and pharmacokinetics of morphine in rats.,

J Pharm Pharmacol, 61(5), 593-597, 2009.

 

 

* Makiko Kokudai, Naoki Inui, Kazuhiko Takeuchi, Toshiyuki Sakaeda, Yoshiyuki Kagawa, Hiroshi Watanabe. :
Effects of Statins on the Pharmacokinetics of Midazolam in Healthy Volunteers.

J Clin Pharmacol,49(5), 568-73, 2009.

 

 

* Yuichi Muraki Takuya Iwamoto, Yoshiyuki Kagawa, Hiroyuki Sakurai, Masanobu Usui, Shuji Isaji, ShinjiUemoto, Masahiro Okuda. :
The Impact of Total Bilirubin on Plasma Micafungin Levels in Living-Donor LiverTransplantation Recipients with Severe Liver Dysfunction.

Biol. Pharm. Bull.32(4), 750-754, 2009.

 

 

* 岡本剛,坂本達一郎,木村緑,薗田明広,森典子,前田利男,賀川義之:
バンコマイシンクリアランスの予測のおける血清シスタチンCの有用性

TDM研究, 26(1), 28-34, 2009.

 

 

* 中島優太,金子貴則,近都正幸,渡邉崇之,小菅和仁,松山耐至,村越邦孫,賀川義之,山田浩:
平成20年度診療報酬等の改訂に伴う後発医薬品の使用状況に関する保険薬局へのアンケート調査

臨床薬理, 40(6), 295-302, 2009.

 

 

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2007〜2008

* Takashi Okura, Tadahiro Ozawa, Yoshihiko Ito, Midori Kimura, Yoshiyuki Kagawa, Shizuo Yamada.
Enhancement by grapefruit juice of morphine antinociception.

Biol Pharm Bull.31(12) 2338-2341, 2008.

 

 

* Yasuaki Mino, Takafumi Naito, Tomomi Matsushita, Atsushi Otsuka, Tomomi Ushiyama, Seiichiro Ozono, Akira Hishida, Yoshiyuki Kagawa, Junichi Kawakami.
Comparison of pharmacokinetics of mycophenolic acid and its glucuronide between patients with lupusnephritis and with kidney transplantation.

Ther Drug Monit.30(6) 656-661, 2008.

 

 

* Takafumi Naito, Yasuaki Mino, Atsushi Otsuka, Tomomi Ushiyama, Seiichiro Ozono, Yoshiyuki Kagawa, and Junichi Kawakami
Influence of metal cations on plasma trough concentration of mycophenolic Acid and its glucuronide intacrolimus-treated and cyclosporine-treated kidney transplant recipients.

Biol Pharm Bull.31(6) 1292-1296, 2008

 

 

* Yoshiyuki Kagawa, Ichiro Noge, Masamune Higashigawa, and Yoshihiro Komada.
Combined antitumor effect of cyclophosphamide and bromodeoxyuridine in BDF1 mice bearing L1210ascites tumors.

Biol Pharm Bull,31(1) 57-61, 2008

 

 

* Yasuaki Mino, Takafumi Naito, Tomomi Matsushita, Yoshiyuki Kagawa, Junichi Kawakami.
Simultaneous determination of mycophenolic acid and its glucuronides in human plasma using isocraticion pair high-performance liquid chromatography.

J Pharm Biomed Anal,46(3) 603-608, 2008

 

 

* Shinya Uchida, Yasuhiro Kato, Kazufumi Hirano, Yoshiyuki Kagawa and Shizuo Yamada.
Brain neurotransmitter receptor-binding characteristics in rats after oral administration of haloperidol,risperidone and olanzapine.

Life Sci,80(17) 1635-1640, 2007

 

 

* Go Okamoto, Tatsuichiro Sakamoto, Midori Kimura, Yoshiyuki Ukishima, Akihiro Sonoda, Noriko Mori, Yasuhiro Kato, Toshio Maeda and Yoshiyuki Kagawa.
Serum cystatin C as a better marker of vancomycin clearance than serum creatinine in elderly patients.

Clin Biochem, 40(7) 485-490, 2007

 

 

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