Providing optimum dosage forms and pharmacotherapy for our patients

It is important to provide an optimum drug dosage forms and personalized pharmaceutical therapy to enhance their benefits for patients. With those in mind, we are developing confectionary shaped dosage forms, orally disintegrat ing tablets and pre-mixed injections, and subjecting them clinical evaluations. In order to provide optimal pharma cotherapy for our patients, it is essential to understand the characteristics of both the pharmacokinetics (PK) an d pharmacodynamics (PD) of drugs, along with factors related to inter-individual variations. We are also investiga ting the relationship between PK and PD relationship in basic and clinical studies, as well as the clinical impact of the drug interactions, and genetic polymorphisms of drug-metabolizing enzymes, transporters and receptors. Fol lowing are our main areas of investigative focuses:

1) Development and clinical evaluation of confectionary shaped dosage forms, orally disintegrating tablets, and pre-mixed injections.

2) Clinical evaluation of formulations and generic drugs based on medical care cost analysis.

3) PK/PD analyses of drugs for optimal and personalized pharmaceutical therapies.

4) Clinical impacts of drug interactions and genetic polymorphisms of drug-metabolizing enzymes, transporters and receptors

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