Friday, September 7

Mukaiyama Award Lecture

M-2　(10：20-11：10）Chairman: Keiichi AJITO (Meiji Seika Pharma Co., Ltd.)

「Accelerated C–H Activation Reactions: A Shortcut to Molecular Complexity from Chemical Feedstock」

（The Scripps Research Institute, USA）Jin-Quan Yu

Pd(II)-catalyzed enantioselective and position-selective C–H activation reactions are developed using mono-N-protected chiral amino acid ligands. C–H activation intermediates are characterized, offering insights into the origin of the observed stereoselectivity. Most importantly, these chiral ligands are found to accelerate drastically C–H activation reactions, shortening the reaction time from two days to 20 minutes.

Copyright © The 29th Seminar on Synthetic Organic Chemistry All Rights Reserved.