9月7(金):
第29回有機合成化学セミナー 3日目(有機合成化学協会創立70周年記念シンポジウム

Mukaiyama Award 受賞講演

M-2  (10:20-11:10)      (座長 (Meiji Seikaファルマ)味戸 慶一)

「Accelerated C–H Activation Reactions: A Shortcut to Molecular Complexity from Chemical Feedstock」

(The Scripps Research Institute, USAJin-Quan Yu


Pd(II)-catalyzed enantioselective and position-selective C–H activation reactions are developed using mono-N-protected chiral amino acid ligands. C–H activation intermediates are characterized, offering insights into the origin of the observed stereoselectivity. Most importantly, these chiral ligands are found to accelerate drastically C–H activation reactions, shortening the reaction time from two days to 20 minutes.



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第29回有機合成化学セミナー(2012)
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