University of Shizuoka School of Pharmaceutical Sciences, Dept. of Biochemistry
The research areas of our laboratory are glycobiology and pathobiochemistry. We explore the fundamental roles of glycans in life, which is the frontier of life science. Specifically, we will elucidate not only the functions of glycans in normal individuals, such as “the regulatory mechanisms of intercellular signals” that regulate development and stem cell functions by glycosylation, but also the functions of glycans in pathological conditions such as “viral infections”, “neurological diseases”, and “cancer”. Furthermore, we aim to develop new technologies and original innovative drug discovery using glycans in order to contribute to the realization of a healthy and long-lived society.
TOPICS NEW（2023）
10.2 Publications (2023) UPDATE
10.2 Topics UPDATE
TOPICS NEW（2022）
12.1 Topics UPDATE
11.16 Publications (2023) UPDATE
11.16 Topics UPDATE
9.7 Publications (2022) UPDATE
8.25 Topics UPDATE
7.12 Publications (2022) UPDATE
4.21 Topics UPDATE
3.30 Publications (2022) UPDATE
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Glyco-science World
Many forms of creature ranging from animal cells to bacteria or viruses possess glycoconjugates on their surfaces. An integrated understanding of life cannot be achieved without an understanding of the glycans that every cell is clothed with. Glycans are characterized by their diversity in structure and function, and by the fact that their expression levels are regulated independently of the genome. Therefore, glycoscience (the biological science on glycoconjugates) has become one of the most important fields in the post-genome era.
We are interested in all phenomena involving glycans. In particular, we investigate the role of glycoconjugates in important biological processes including Notch signaling, which regulates development and stem cell function, diseases in dire need of overcoming, such as viral infections and cancer, and neural transmission related to memory. The results obtained are then applied to the development of new chemical biology tools and original innovative drug discovery for creating a healthy and long-lived society. Curiosity and passion are keys to success. Come explore the world of glycoscience with us!
We are looking for highly motivated graduate students from all over the world. Recently, we have hosted graduate students from countries such as Malaysia, China, and Bangladesh in our laboratory. If you are interested in our research, please contact us by e-mail.