研究業績
英文原著
2024
NEW !Asymmetric Fluorocyclization of
Difluoroalkenes with Concomitant Formation of a Trifluoromethyl Group
C. Igarashi, T. Mayumi, H. Egami*, and Y.
Hamashima*
Org. Lett.
2024, ASAP DOI:10.1021/acs.orglett.4c00312
Benzylic C(sp3)–H Alkoxylation
through
Visible-Light-Driven Oxidative Radical-Polar Crossover
K. Yamashita*, F. Kawahara, and Y.
Hamashima*
Asian J. Org. Chem.
2024, ASAP DOI:10.1002/ajoc.202300662
2023
Chiral Macrocyclic Catalysts for
the
Enantioselective Addition of Lithium Acetylides to Ketones
K. Yamashita, Y. Tabata, K. Yamakawa, T.
Mochizuki, K. Matsui, M. Hatano*, and K. Ishihara*
J. Am. Chem. Soc.
2023, 145, 48, 26238–26248. DOI:10.1021/jacs.3c08905
Charged chiral derivatization for
enantioselective imaging of d-,l-2-hydroxyglutaric acid using ion
mobility spectrometry/mass spectrometry
E. Sugiyama, Y. Nishiya, K. Yamashita, R.
Hirokawa, Y. Iinuma, T. Nirasawa, H. Mizuno, Y. Hamashima, and
K. Todoroki*
Chem. Commun.
2023, 59, 10916-10919. DOI:org/10.1039/d3cc01963b
Switching Regioselectivity in the
Asymmetric Bromocyclization of Difluoroalkenes Catalyzed by a Chiral
Bisphosphine Oxide
Y. Nakahara, R. Hirokawa, S. Uchida, K.
Yamashita, and Y. Hamashima*
Synlett
2023, 34, 20, 2476-2480. DOI:10.1055/a-2117-8816
Experimental and Computational
Investigation of Facial Selectivity Switching in
Nickel–Diamine–Acetate-Catalyzed Michael Reactions
Y. Sohtome, S. Komagawa, A. Nakamura, D.
Hashizume, S. Lectard, M. Akakabe, Y. Hamashima, M. Uchiyama, and M.
Sodeoka*
J. Org. Chem.
2023, 88, 7764–7773.
DOI:org/10.1021/acs.joc.2c02732
Enantioselective Synthesis of
Bromodifluoromethyl-containing Oxazolines by Concerted Lewis/Brønsted
Base Catalysis with Chiral Bisphosphine Oxide
R. Hirokawa, Y. Nakahara, S. Uchida, K.
Yamashita, and Y. Hamashima
Chem. Asian J.
2023, 18, e202300141.
DOI:org/10.1002/asia.202300141
Asymmetric Fluorofunctionalizations
with
Carboxylate-Based Phase-Transfer Catalysts
H. Egami, and Y.
Hamashima*
Chem. Rec. 2023, 23, e202200285.
DOI:org/10.1002/tcr.202200285
Amide-Ligand-Promoted
Silver-Catalyzed C–H
Fluorination via Radical/Polar Crossover
K. Yamashita, Y. Fujiwara, and Y.
Hamashima*
J. Org. Chem.
2023, 88, 3,
1865–1874.
DOI:org/10.1021/acs.joc.2c02575
2022
Mechanistic Details of Asymmetric
Bromocyclization with BINAP
Monoxide: Identification of Chiral Proton-Bridged Bisphosphine
Oxide Complex and Its Application to Parallel Kinetic Resolution
K. Yamashita, R. Hirokawa, M. Ichikawa, T.
Hisanaga, Y. Nagao, R. Takita,
K. Watanabe, Y. Kawato and Y. Hamashima*
J. Am. Chem. Soc.
2022, 144, 9,
3913-3924.
DOI:org/10.1021/jacs.1c11816
2021
Structure Dependence in Asymmetric
Deprotonative Fluorination
and Fluorocyclization Reactions of Allylamine Derivatives with
Linked Binaphthyl Dicarboxylate Phase-Transfer Catalyst
T. Niwa, K. Nishibashi, H. Sato, K. Ujiie,
K. Yamashita, H. Egamiand Y. Hamashima*
J. Am. Chem. Soc.
2021, 143, 40,
16599-16609.
DOI:org/10.1021/jacs.1c06783
Design of synthetic polymer
nanoparticles that inhibit glucoseabsorption from the intestine
H. Koide, N. Hayashi, G. Yasuno, A.
Okishima, Y. Hoshino, H. Egami, Y. Hamashima, N. Oku, T.
Asai*
Biochemical and Biophysical Research Communications 2021, 561, 1-6. DOI:org/10.1016/j.bbrc.2021.05.005
Dearomative enantio- and
diastereoselective
difluorination of resorcinol derivatives
M. Otsubo, K. Sakimoto, H. Egami and Y.
Hamashima*
Tetrahedron
2021, 96, 132355.
. DOI:org/10.1016/j.tet.2021.132355
Enhancement of target toxin
neutralization
effect in vivo by
PEGylation of multifunctionalized lipid nanoparticles
H. Koide, H. Suzuki, H.
Ochiai, H. Egami,
Y. Hamashima, N. Oku, T. Asai
Biochemical and Biophysical Research Communications
2021, 561, 1-6.
DOI:org/10.1016/j.bbrc.2021.03.073
Dual-Role Catalysis
by Thiobenzoic Acid in
Co-H Arylation under Photoirradiation
F. Kobayashi, M. Fujita, T. Ide, Y. Ito, K.
Yamashita, H. Egami, and Y. Hamashima*
Acs Catal. 2021, 11, 82-87.
DOI:10.1021/acscatal.0c04722
2020
Oxidative and Redox-Neutral
Approaches to
Symmetrical Diamines and Diols by Single Electron Transfer/Hydrogen
Atom Transfer Synergistic Catalysis
M. Fujita, F. Kobayashi, T. Ide, H. Egami,
Y. Hamashima*
Eur. J. Org. Chem.
2020, 7151–7155.
DOI:10.1002/ejoc.202001329
Asymmetric Dearomatizing
Fluoroamidation of
Indole Derivatives with Dianionic Phase-Transfer Catalyst
H. Egami, R. Hotta, M. Otsubo, T. Rouno, T.
Niwa, K. Yamashita and Y. Hamashima*
Org. Lett.
2020, 22, 5656-5660.
DOI:10.1021/acs.orglett.0c02026
Fluorofunctionalizations of C-C Multiple
Bonds and C-H Bonds
H. Egami*
Chem. Pharm. Bull. 2020, 68, 491-511. DOI:
10.1248/cpb.c19-00856
Asymmetric Dearomative Fluorination of
2-Naphthols with Dicarboxylate Phse-Transfer Catalyst
H. Egami, T.
Rouno, T.
Niwa, K .Masuda, K. Yamashita and Y. Hamashima*
Angew.
Chem., Int. Ed.
2020, 59, 14101-14105. DOI:
10.1002/anie.202005367
Synfacts
2020, 16(08):,
0966 DOI:
10.1055/s-0040-01707436
18F-Labeled dihydromethidine: Positron
emission tomography radiotracer for imaging of reactive oxygen species
in intact brain
H. Egami, S. Nakagawa, Y. Katsura, M.
Kanazawa, S.
Nishiyama, T. Sakai, Y. Arano, H. Tsukada, O. Inoue, K. Todoroki * and
Y. Hamashima*
Org. Biomol. Chem.
2020, 18, 2387-2391.
DOI:
10.1039/D0OB00126K
2019
High Efficiency Microwave Flow Chemistry
toward Synthesis of Functional Materials and Pharmaceutical Cores
J. P. Barham, E. Koyama, J. Sugiyama, Y.
Norisane, H. Egami and Y. Hamashima*
Ampere 2019,
409-417. DOI:
10.4995/Ampere2019.2019.9860
Ammonium Salt-Accelerated Hydrazinolysis of
Unactivated Amides: Mechanistic Investigation and Application to a
Microwave Flow Process
M. Noshita, Y. Shimizu, H. Morimoto, S. Akai, Y.
Hamashima, N. Ohneda, H. Odajima and T. Ohshima*
Org. Process Res. Dev. 2019, 23, 588-594. DOI:
10.1021/acs.oprd.8b00424
Consice Synthesis of TAN1251C
Y. Nagasawa, T. Asakawa, S. Shintaku, A. Masuda,
K. Matsumura, M. Inai, Y. Ishikawa, M. Egi, Y. Hamashima and T. Kan*
Heterocycles 2019, 99, 1095-1116. DOI:
10.3987/COM-18-S(F)78
Enantioselective
5-exo-Fluorocyclization of
Ene-Oximes
T. Rouno, T. Niwa, K. Nishibashi, N. Yamamoto,
H. Egami and Y. Hamashima*
Molecules 2019, 24, 3464. DOI:
10.3390/molecules24193464
Thiocyanation of Aromatic and
Heteroaromatic Compounds with 1-Chloro-1,2-benziodoxol-3-(1H)-one and
(Trimethylsilyl)isothiocyanate
Y. Ito, A. Touyama, M. Uku, H. Egami*, and Y.
Hamashima*
Chem. Pharm. Bull. 2019, 67, 1015-1018. DOI:
10.1248/cpb.c19-00352
Design of Synthetic
Polymer Nanoparticles Specifically Capturing Indole, a Small Toxic
Molecule
A. Okishima, H. Koide*,
Y. Hoshino, H. Egami, Y.
Hamashima, N. Oku, and T. Asai
Biomacromolecules. 2019,
20,
1644–1654. DOI:
10.1021/acs.biomac.8b01820
Sequestering
and inhibiting a vascular endothelial growth factor in vivo by systemic
administration of a synthetic polymer nanoparticle
H. Koide, K. Yoshimatsu, Y. Hoshino, S. Ariizumi,
A. Okishima, T. Ide, H. Egami, Y. Hamashima, Y. Nishimura, H. Kanazawa,
Y. Miura, T. Asai, N. Oku*, and K. J. Shea*
J. Control. Release. 2019,
295, 13-20. DOI:
10.1016/j.jconrel.2018.12.033
Rigorous
control of vesicle-forming lipid pKa by fluorine-conjugated
bioisosteres for gene-silencing with siRNA
A. Okamoto, H. Koide, N. Morita, Y. Hirai, Y.
Kawato, H. Egami, Y. Hamashima, T. Asai, T. Dewa, and N. Oku*
J. Control. Release. 2019,
295, 87-92. DOI:
10.1016/j.jconrel.2018.12.044
Practical
and Scalable Organic Reactions with Flow Microwave Apparatus
H. Egami, and Y.
Hamashima*
Chem. Rec. 2019,
19, 157-171. DOI:
10.1002/tcr.201800132
2018
C-alkylation of N-alkylamides with
styrenes in air and scale-up using a microwave flow reactor
J. P. Barham, S, Tamaoki, H. Egami,
N, Ohneda, T, Okamoto, H, Odajima, and Y.
Hamashima*
Org. Biomol. Chem. 2018, 16,
7568-7573. DOI:
10.1039/C8SC02965B
Regio- and chemoselective Csp3–H
arylation of benzylamines by
single electron transfer/hydrogen atom transfer synergistic
catalysis
T. Ide, J. P. Barham, M. Fujita, Y. Kawato, H. Egami,
Y.
Hamashima*
Chem. Sci. 2018,
9, 8453-8460. DOI:
10.1039/C8SC02965B
Asymmetric
Fluorination of Cyclic
Tetrasubstituted Alkenes with a Pendant Amide Groups under Dianionic
Phase-transfer Catalysis
T. Niwa, K. Ujiie, H. Sato, H. Egami, Y. Hamashima*
Chem. Pharm. Bull. 2018,
66, 920-922. DOI:
10.1248/cpb.c18-00551
Scalable
Microwave-assisted
Johnson-Claisen Rearrangement with Continuous Flow Microwave System
H. Egami, S. Tamaoki, M. Abe, N. Ohneda, T. Yoshimura,
T. Okamoto, H. Odajima, N. Mase, K. Takeda, Y. Hamashima*
Org. Process Res. Dev. 2018, 22, 1029-1033. DOI:
10.1021/acs.oprd.8b0018
Redox-neutral C−H cyanation of
tetrahydroisoquinolines under photoredox catalysis
T. Ide, K. Shimizu, H. Egami, Y. Hamashima*
Tetrahedron Lett. 2018,
59, 3258-3261.
DOI: 10.1016/j.tetlet.2018.07.030
(E)-3-[4-(Pent-4-en-1-yloxy)phenyl]acrylic
Acid
H. Egami, T. Sawairi, S. Tamaoki, N. Ohneda, T. Okamoto, H.
Odajima, Y. Hamashima*
Molbank 2018,
2018, M996 DOI: 10.3390/M996
Simple
Photo-induced Trifluoromethylation of Aromatic Rings
H. Egami*, Y. Ito, T. Ide, S. Masuda, Y. Hamashima*
Synthesis 2018, 50, 2948-2953. DOI:
10.1055/s-0037-1609759
Enantioselective
Bromocyclization of Allylic Amides Mediated by Phosphorus Catalysis
Y. Kawato, Y.
Hamashima*
Synlett 2018, 29, 1257-1271. DOI:
10.1055/s-0036-1591579
Enantioselective
Synthesis of Nelfinavir via Asymmetric Bromocyclization of Bisallylic
Amide
Y. Nagao, T. Hisanaga, T. Utsumi, H. Egami, Y. Kawato, Y.
Hamashima*
J. Org. Chem. 2018, 83, 7290-7295. DOI:
10.1021/acs.joc.8b00039
Highlighted in Synfacts
2018, 14, 900
DOI: 10.1055/s-0037-1610560
Dianionic
Phase-Transfer Catalyst for Asymmetric Fluorocyclization
H. Egami, T. Niwa, H. Sato, R. Hotta, T. Rouno, Y. Kawato, Y.
Hamashima*
J. Am. Chem. Soc. 2018, 140, 2785-2788. DOI:
10.1021/jacs.7b13690
Highlighted in Synfacts
2018, 14, 534. DOI:
10.1055/s-0037-1609661
Photofluorination
of Aliphatic C–H Bonds Promoted by the Phthalimide Group
H. Egami*, S. Masuda, Y. Kawato, Y. Hamashima*
Org. Lett. 2018, 20,
1367-1370. DOI:
10.1021/acs.orglett.8b00133
2017
Desymmetrization
of Bisallylic Amides through Catalytic Enantioselective
Bromocyclization with BINAP Monoxide
Y. Nagao, T. Hisanaga, H. Egami, Y. Kawato, Y. Hamashima*
Chem. Eur. J. 2017, 23, 16758–16762 DOI:
10.1002/chem.201704847 《Most Accessed 11/2017》
Benzylic
C–H Trifluoromethylation via Photoenol
T. Ide, S. Masuda, Y. Kawato, H. Egami, Y. Hamashima*
Org. Lett. 2017, 19,
4452–4455 DOI:
10.1021/acs.orglett.7b01971
Total
Synthesis of TAN1251C via Diastereoselective Construction of the
Azaspiro Skeleton
Y. Nagasaka, S. Shintaku, K. Matsumura, A. Masuda, T. Asakawa,
M. Inai, M. Egi, Y. Hamashima, Y. Ishikawa, and T. Kan*
Org. Lett. 2017, 19, 3839-3842 DOI:
10.1021/acs.orglett.7b01718
Synthetic
Study on Pactamycin: Stereoselective Synthesis of the Cyclopentane Core
Framework
A. Goto, S. Yoshimura, Y. Nakao, M. Inai, T. Asakawa, M. Egi,
Y. Hamashima, M. Kondo, and T. Kan*
Org. Lett. 2017, 19, 3358-3361 DOI:
10.1021/acs.orglett.7b01257
Enantioselective
Allyl-, and Allenylboration of Aldehydes Catalyzed by Chiral Hydroxyl
Carboxylic Acid
Y. Ota, Y. Kawato, H. Egami, Y. Hamashima*
Synlett 2017, 28, 976-980 DOI:
10.1055/s-0036-1588690
2016
Stereoselective
Construction of 2-Vinyl 3-Hydroxybenzopyran Rings: Total Syntheses of
Teadenols A and B
R. Yoshida, H. Ouchi, A. Yoshida, T. Asakawa, M. Inai, M. Egi,
Y. Hamashima* and T. Kan*
Org. Biomol. Chem. 2016, 14, 10783-10786 DOI/10.1039/C6OB02004F
α-Functionalization
of Tetrahydroisoquinolines with Activated Alkyl Bromide under
Photoredox Catalysis
T. Ide, K. Shimizu, Y. Kawato, H. Egami, and Y. Hamashima*
Heterocycles 2017, 95, 738-747. DOI :
10.3987/COM-16-S(S)73
Difunctionalization
of Alkenes Using 1-Chloro-1,2-benziodoxol-3-(1H)-one
H. Egami*, T. Yoneda, M. Uku, T. Ide, Y. Kawato, and Y.
Hamashima*
J. Org. Chem. 2016,
81, 4020-4030. DOI/10.1021/acs.joc.6b00295
Practical Total Syntheses of Acromelic Acids A and B
M. Inai, H. Ouchi, A. Asahina, T. Asakawa, Y. Hamashima*, and T. Kan*
Chem. Pharm. Bull. 2016, 64, 723-732. DOI/org/10.1248/cpb.c16-00009
Synthesis of methylated
catechins and theaflavins using 2-nitrobenzenesulfonyl group to protect
and deactivate phenol
T. Kan, T. Asakawa, Y. Kawabe, A. Yoshida, Y. Aihara, T. Manabe, Y.
Hirose, A. Sakurada, M. Inai, Y. Hamashima, T. Furuta, and T. Wakimoto
J. Antibiot. 2016, 69, 299-312. DOI/10.1038/ja.2016.14
Highly Enantioselective Bromocyclization of Allylic Amides
with a P/P=O Double-site Lewis Base Catalyst
Y. Kawato, H. Ono, A. Kubota, Y. Nagao, N. Morita, H. Egami, and Y.
Hamashima*
Chem. Eur. J. 2016, 22, 2127-2133. DOI/10.1002/chem.201503153
2015
Benzylic C–H Trifluoromethylation of Phenol Derivatives
H. Egami, T. Ide, Y. Kawato, and Y. Hamashima*
Chem. Commun. 2015, 51, 16675–16678. DOI: 10.1039/C5CC07011B
Asymmetric Fluorolactonization with a Bifunctional Hydroxyl
Carboxylate Catalyst
H. Egami, J. Asada, K. Sato, D. Hashizume, Y. Kawato, and Y. Hamashima*
J. Am. Chem. Soc. 2015, 137, 10132–10135. DOI:
10.1021/jacs.5b06546
Stereocontrolled Total Syntheses of Optically Active
Furofuran Lignans
M. Inai, R. Ishikawa, N. Yoshida, N. Shirakawa, Y. Akao, Y. Kawabe, T.
Asakawa, M. Egi, Y. Hamashima*, T. Kan*
Synthesis 2015, 47, 3513-3521. DOI: 10.1055/s-0034-1378812
2-[(Neopentyl glycolato)boryl]phenyl Triflates and Halides
for Fluoride-Ion-Mediated Generation of Functionalized Benzynes
T. Ikawa,* R. Yamamoto, A. Takagi, T. Ito, K. Shimizu, M. Goto, Y.
Hamashima, S. Akai*
Adv. Synth. Catal. 2015, 357,
2287-2300. DOI: 10.1002/adsc.201500315
Concise Synthesis of Binaphthol-derived Chiral Dicarboxylic
Acids
H. Egami, K. Sato, J. Asada, Y. Kawato, Y. Hamashima*
Tetrahedron 2015, 71, 6384–6388. DOI: 10.1016/j.tet.2015.05.041
Advanced Dress-up Chiral Columns: New Removable Chiral
Stationary Phases for Enantioseparation of Chiral Carboxylic Acids
K. Todoroki, Y. Ishii, T. Ide, J.Z. Min, K. Inoue, X. Huang, W. Zhang,
Y. Hamashima, T. Toyo'oka*
Analytica Chimica Acta 2015, 882, 101-111.
DOI: org/10.1016/j.aca.2015.03.037
Enantioselective Bromocyclization of Allylic Amides
Catalyzed by
BINAP Derivatives
Y. Kawato, A. Kubota, H. Ono, H. Egami, Y, Hamashima*
Org. Lett. 2015, 17, 1244-1247. DOI:10.1021/acs.orglett.5b00220
Development of a Highly Efficient Single-mode Microwave
Applicator
with a Resonant Cavity and Its Application to Continuous Flow Syntheses
S. Yokosawa, N. Ohneda, K. Muramatsu, T. Okamoto, H, Odashima, T.
Ikawa, J. Sugiyama, M. Fujita, T. Sawairi, H. Egami, Y, Hamashima, M.
Egi, S. Akai*
RSC Adv. 2015, 5, 10204-10210. DOI:10.1039/C4RA12428F
2014
Dual Catalysis with Copper and
Rhenium for Trifluoromethylation of
Propargylic Alcohols: Efficient Synthesis of α-Trifluoromethylated
Enones
H. Egami, T. Ide, M. Fujita, T. Tojo, Y, Hamashima*, M.
Sodeoka*
Chem. Eur. J. 2014, 20, 12061–12065. DOI:10.1002/chem.201403447
Total Syntheses of (+)-Sesamin and
(+)-Sesaminol
R. Ishikawa, N. Yoshida, Y.Akao, Y. Kawabe, M. Inai, T. Asakawa, Y.
Hamashima*, T. Kan*
Chem. Lett. 2014, 43, 1572-1574. DOI:10.1246/cl.140613
Practical synthesis of natural
plant-growth regulator
2-azahypoxanthine, its derivatives, and biotin-labeled probes
K. Ikeuchi, R. Fujii, S. Sugiyama, T. Asakawa, M. Inai, Y. Hamashima,
J. H. Choi, T. Suzuki, H. Kawagishi*, T. Kan*
Org. Biomol. Chem., 2014, 12, 3813-3815. DOI:10.1039/C4OB00705K
Stereocontrolled Total Synthesis of
Hedyotol A
Y. Kawabe, R. Ishikawa, Y. Akao, A. Yoshida, M. Inai, T. Asakawa, Y.
Hamashima*, T. Kan*
Org. Lett., 2014, 16, 1976-1979. DOI:10.1021/ol500524y
Practical Total Syntheses of
Acromelic Acids A and B
H. Ouchi, A. Asahina, T. Asakawa, M. Inai, Y. Hamashima*, T.
Kan*
Org. Lett., 2014, 16, 1980-1983. DOI:10.1021/ol500529w
Practical Synthesis of Kainoids: A
New Chemical Probe Precursor and
a Fluorescent Probe
S. Sasaki, H. Suzuki, H. Ouchi, T. Asakawa, M. Inai, R. Sakai, K.
Shimamoto, Y. Hamashima*, T. Kan*
Org. Lett. 2014, 16, 564-567. DOI:10.1021/ol403434e
Synthetic Studies of Fisetin,
Myricetin and Nobiletin Analogs and
Related Probe Molecules
A. Hiza, Y. Tsukaguchi, T. Ogawa, M. Inai, T. Asakawa, Y. Hamashima*,
T.
Kan*
HETEROCYCLES 2014, 88, 1371-1396. DOI: 10.3987/COM-13-S(S)107
2013
Stereocontrolled total synthesis of
sphingofungin E
K. Ikeuchi, M. Hayashi, T. Yamamoto, M. Inai, T. Asakawa, Y. Hamashima,
T. Kan
Eur. J. Org. Chem. 2013, 30, 6789-6792. DOI: 10.1002/ejoc.201301065
Chemoselective Hydrogenation
Reaction of Unsaturated Bonds in the
Presence of o-Nitrobenzenesulfonyl Group
A. Kawanishi, C. Miyamoto, Y. Yabe, M. Inai, T. Asakawa, Y. Hamashima,
H. Sajiki, T. Kan*
Org. Lett. 2013, 15, 1306-1309. DOI: 10.1021/ol4002448
Synthesis of Theaflavin via
Biomimetic Oxidative Coupling Reaction
Y. Kawabe, Y. Aihara, Y. Hirose, A. Sakurada, A. Yoshida, M. Inai, T.
Asakawa, Y. Hamashima*, T. Kan*
Synlett 2013, 479-482. DOI: 10.1055/s-0032-1318131
Epidithiodiketopiperazine as a
pharmacophore for protein lysine
methyltransferase
G9a inhibitors: Reducing cytotoxicity by structural simplification
S. Fujishiro, K. Dodo, E. Iwasa, Y. Sohtome, Y. Hamashima, A. Ito, M.
Yoshida, M. Sodeoka*
Bioorg. Med. Chem. Lett. 2013, 23, 733-736. DOI:
10.1016/j.bmcl.2012.11.087
2012
Catalytic Desymmetrization of Cyclohexadienes via Asymmetric
Bromolactonization
K. Ikeuchi, K. Ido, S. Yoshimura, T. Asakawa, M. Inai, Y. Hamashima*,
T.
Kan*
Org. Lett. 2012, 14, 6016-6019.
Stereocontrolled Total Synthesis of (+)- UCS1025A
K. Uchida, T. Ogawa, Y. Yasuda, H. Mimura, T. Fujimoto, T. Fukuyama, T.
Wakimoto, T. Asakawa, Y. Hamashima*, T. Kan*
Angew. Chem., Int. Ed. 2012, 51, 12850-12853.
Total Synthesis of (-)-Lemonomycin
A. Yoshida, M. Akaiwa, T. Asakawa, Y. Hamashima, S. Yokoshima, T.
Fukuyama, T. Kan*
Chem. Eur. J. 2012, 18, 11192-11195.
A Short-step Asymmetric Synthesis of Dehydrodiconifery Alcohol (DCA)
via C-H Insertion Reaction
S. Matsumoto, T. Asakawa, Y. Hamashima*, T. Kan*
Synlett 2012, 1082-1084.
Copper-Catalyzed Trifluoromethylation of Allylsilanes
R. Shimizu, H. Egami, Y. Hamashima*, M. Sodeoka*
Angew. Chem., Int. Ed. 2012, 51, 4577-4580.
Catalytic Asymmetric Mono-fluorination of a-Keto Ester: Synthesis of
Optically
Active a-Hydroxy-b-fluoro Esters and a-Amino-b-fluoro Esters
S. Suzuki, Y. Kitamura, S. Lectard, Y. Hamashima*, M. Sodeoka*
Angew. Chem., Int. Ed. 2012, 51, 4581-4585.
Synthesis and Biological Activities of Chaetocin and its Derivatives
M. Sodeoka, K. Dodo, Y. Teng, K. Iuchi, Y. Hamashima, E. Iwasa, S.
Fujishiro
Pure Appl. Chem. 2012, 84, 1369-1378.
2011年以前は PDF で。
総説
英文総説
Chemical synthesis of tea polyphenols and related compounds
T. Asakawa, Y. Hamashima, T. Kan
Current Pharmaceutical Design 2013, 19,
6207-6217.
Epipolythiodiketopiperazine Alkaloids: Total Syntheses and
Biological Activities
E. Iwasa, Y. Hamashima, M. Sodeoka
Israel J. Chem. 2011, 51, 420-433.
Recent Advances in Catalytic Enantioselective Fluorination Reactions
S. Lectard, Y. Hamashima, M. Sodeoka
Adv. Synth. & Catal. 2010, 352, 2708-2732.
Development of Novel Catalytic Asymmetric Reactions Using Cationic
Group-10 Metal Complexes: With a Special Focus on Reactions in which
Palladium Enolates Plays a Key Role
Y. Hamashima, M. Sodeoka
TCI MAIL 2010, 140, 2-16.
Chiral Pd aqua complex-catalyzed asymmetric C-C bond-forming
reactions: a Brønsted acid-base cooperative system
M. Sodeoka, Y. Hamashima
Chem. Commun. 2009, 5787-5798.
Catalytic Enantioselective a-Fluorination of Carbonyl Compounds
Using Chiral Transition Metal Complexes
Y. Hamashima, M. Sodeoka
J. Synth. Org. Chem., Jpn. 2007, 65, 1099-1107.
Acid-Base Catalysis of Chiral Palladium Complexs: Development of
Novel Asymmetric Reactions and Their Application to Synthesis of Drug
Candidates
Y. Hamashima
Chem. Pharm. Bull. 2006, 54, 1351-1364.
Enantioselective Fluorination Reactions Catalyzed by Chiral
Palladium Complexes
Y. Hamashima, M. Sodeoka
Synlett 2006, 1467-1478.
Development of Catalytic Asymmetric Reactions via Chiral Palladium
Enolates
Y. Hamashima, M. Sodeoka
Chem. Rec. 2004, 4, 231-242.
和文総説
「アニオン性相間移動触媒の創製と不斉フッ素化反応の開発」
江上寛通, 濱島義隆
有機合成化学協会誌 2022, 80, 632-644.
「遷移金属錯体の酸・塩基作用を利用する触媒的不斉反応の開発」
濱島義隆, 袖岡幹子
有機合成化学協会誌 2011, 69, 972-984.
「カチオン性10族金属触媒を用いた不斉触媒反応の新展開:パラジウムエノラートを鍵とする反応を中心として」
濱島義隆, 袖岡幹子
TCIメール 2008, 140, 2-21.
「パラジウム触媒による不斉フッ素化反応」
濱島義隆, 袖岡幹子
触媒 2007, 49, 20-24.
「Pd錯体による酸/塩基反応を鍵とする触媒的不斉反応の開発」
濱島義隆
Yakugaku Zasshi 2005, 125, 785-793.
「エナンチオ選択的フッ素化反応の新展開」
濱島義隆, 袖岡幹子
ファルマシア 2004, 40, 507-511.
「触媒的不斉マイケル反応」
濱島義隆, 袖岡幹子
ファルマシア 2003, 39, 664-665.
「ルイス酸−ルイス塩基複合多点認識不斉触媒の創製と展開」
金井求, 濱島義隆, 高村昌弘, 柴崎正勝
有機合成化学協会誌 2001, 59, 766-778.
「ルイス酸−ルイス塩基型多点認識不斉触媒の開発」
金井求, 濱島義隆, 柴崎正勝
ファルマシア 1999, 35, 690-694.
図書
「相間移動触媒の設計に基づくオレフィン類の不斉フッ素官能基化反応の開発」
江上寛通,濱島義隆
月刊ファインケミカル 2019年10月号(シーエムシー出版)pp.22–30
「アニオン性相関移動触媒の創成と不斉フッ素化」
江上寛通,濱島義隆
月刊化学工業 2019年9月号(化学工業社)pp.6–13
「学際的創薬科学論」
石川智久,橋本博,濱島義隆,吉成浩一 共著
京都廣川書店
「フロー型マイクロ波照射装置を用いる有機合成」
江上寛通,濱島義隆
化学プロセスのスケールアップ、連続化(技術情報協会)pp.494–506
「不斉ハロ環化反応による高機能性キラル合成素子の開発」
川戸勇士,濱島義隆
有機分子触媒の開発と工業利用(監修: 秋山隆彦, シーエムシー出版)第26章
「有機分子触媒による不斉ブロモ環化反応の開発」
川戸勇士,濱島義隆
月刊ファインケミカル 2017年3月号(シーエムシー出版)pp.12–20
Carbon-Carbon Bond-Forming Reactions via Transmetallation Using
Silyl Enol Ethers
Y. Hamashima, M. Sodeoka
In Comprehensive Chirality (E. M. Carreira, H. Yamamoto et al. Eds.:
Elsevier), Vol. 4, 210-213 (2012).
「いろいろなキラル分子」
濱島義隆
化学と教育, 2009, 57, 148-151.
「マクマリー有機化学 生命反応へのアプローチ」
柴崎正勝 他 監訳 翻訳担当 (2009)
Michael Addition Reactions
Y. Hamashima, M. Sodeoka
In Handbook of C-H Transformations (G. Dyker, Ed.; Wiley-VHC),
Vol. 2, 347-359 (2005)
「Mannich 反応」
濱島義隆, 袖岡幹子
有機合成のための触媒反応103 (檜山為次郎, 野崎京子 編, 東京化学同人) pp.92-93 (2004).
Asymmetric Reactions Catalyzed by Chiral Palladium Aqua and Hydroxo
Complexes
袖岡幹子, 濱島義隆
有機合成創造の軌跡 (有機合成化学協会 編) pp.192-193 (2002).
社会貢献
・ 日本薬学会 会員
・ 日本化学会 会員
・ 有機合成化学協会 会員
・ アメリカ化学会 会員
・ 有機合成化学協会東北・北海道支部常任幹事(2002~2005年度)
・ 理化学研究所客員研究員(2010~2012)
・ 日本薬学会ファルマシアトピックス小委員 (2008-2010年度)
・ 有機合成化学協会東海支部庶務幹事(2012年度)
・ 第29回有機合成化学セミナー実行委員会事務局(2012年)
・ 第12回次世代を担う有機合成化学シンポジウム実行委員長(2014年, 内定)