研究業績 Publications
Publications >>NCBI link
2025
Hirai K, Shirai T, Uehara S, Akamatsu T, Itoh K.
Identification of potential transcriptomic and microRNA markers to assess benralizumab effectiveness
PI3K Pathway Activation in Severe Asthma is Linked to Steroid Insensitivity and Adverse Outcomes
Impact of Antibacterials on the Quality of Anticoagulation Control in Patients Initiating Warfarin Therapy
Vitamin D Receptor rs2228570 Gene Polymorphism Is Associated with Asthma Severity and Exacerbations
Identification of potential transcriptomic and microRNA markers to assess benralizumab effectiveness
J Allergy Clin Immunol. In press
Uehara S, Hirai K, Shirai T, Akamatsu T, Itoh K.PI3K Pathway Activation in Severe Asthma is Linked to Steroid Insensitivity and Adverse Outcomes
J Allergy Clin Immunol Glob. 4:100439(2025)
Sugiyama K, Hirai K, Tsutsumi M, Furuya S, Itoh K.Impact of Antibacterials on the Quality of Anticoagulation Control in Patients Initiating Warfarin Therapy
Am J Cardiovasc Drugs. 25:259-266 (2025)
Uehara S, Hirai K, Shirai T, Otaki H, Akamatsu T, Itoh K.Vitamin D Receptor rs2228570 Gene Polymorphism Is Associated with Asthma Severity and Exacerbations
2024
Suzuki K, Yokokawa T, Kawaguchi T, Takada S, Tamaki S, Kawasaki Y, Yamaguchi T, Koizumi K, Matsumoto T, Sakata Y, Arakawa Y, Ayuhara H, Hosonaga M, Yamaguchi M, Tsuji D.
A multicenter, phase II trial of triplet antiemetic therapy with palonosetron, aprepitant, and olanzapine for highly emetogenic chemotherapy in breast cancer (PATROL-II) Uehara S, Hirai K, Shirai T, Itoh K.
Association of a CYP3A5 gene polymorphism with exacerbation in adult patients with asthma
Impact of once-daily versus multiple-daily dosing of gentamicin on the incidence of acute kidney injury in patients treated with synergistic combinations of antibiotics
Pharmacogenomic study of gemcitabine efficacy in patients with metastatic pancreatic cancer: A multicenter, prospective, observational cohort study (GENESECT study) Hirai K, Kimura T, Suzuki Y, Shimoshikiryo T, Shirai T, Itoh K.
Gene Polymorphisms of NLRP3 Associated With Plasma Levels of 4β-Hydroxycholesterol, an Endogenous Marker of CYP3A Activity, in Patients With Asthma
Changes in estimated glomerular filtration rate in patients administered proton pump inhibitors: a single-center cohort study
A multicenter phase II trial of the triplet antiemetic therapy with palonosetron, aprepitant, and olanzapine for a cisplatin-containing regimen. - PATROL-I
A multicenter, phase II trial of triplet antiemetic therapy with palonosetron, aprepitant, and olanzapine for highly emetogenic chemotherapy in breast cancer (PATROL-II) Uehara S, Hirai K, Shirai T, Itoh K.
Association of a CYP3A5 gene polymorphism with exacerbation in adult patients with asthma
J Allergy Clin Immunol Pract. 12:2180-2182 (2024)
Sugiyama K, Hirai K, Suyama Y, Tsutsumi M.Impact of once-daily versus multiple-daily dosing of gentamicin on the incidence of acute kidney injury in patients treated with synergistic combinations of antibiotics
J Pharm Health Care Sci. 10:40 (2024)
Hatori M, Tsuji D, Suzuki K, Yokokawa T, Kawakami K, Moriyama R, Osada-Tsuchiya M, Otaki A, Nakao M, Yano T, Arakawa Y, Matsuo K, Ohashi Y, Sakata Y, Kogure Y, Tamaki S, Wada A, Taki Y, Sasahira N, Ishii H, Yamaguchi M, Itoh K.Pharmacogenomic study of gemcitabine efficacy in patients with metastatic pancreatic cancer: A multicenter, prospective, observational cohort study (GENESECT study) Hirai K, Kimura T, Suzuki Y, Shimoshikiryo T, Shirai T, Itoh K.
Gene Polymorphisms of NLRP3 Associated With Plasma Levels of 4β-Hydroxycholesterol, an Endogenous Marker of CYP3A Activity, in Patients With Asthma
Clin Pharmacol Ther. 116:147-154（2024）
Murofushi T, Yagi T, Tsuji D, Furushima D, Itoh K, Kawakami J.Changes in estimated glomerular filtration rate in patients administered proton pump inhibitors: a single-center cohort study
Naunyn Schmiedebergs Arch Pharmacol. 397:4927-4938（2024）
Tsuji D, Nakagaki S, Yonezawa I, Suzuki K, Yokokawa T, Kawasaki Y, Yamaguchi T, Kawaguchi T, Hatori M, Matsumoto T, Sakata Y, Yamamoto K, Nishimura T, Kogure Y, Hayashi T, Osawa M, Itoh K, Watanabe M.A multicenter phase II trial of the triplet antiemetic therapy with palonosetron, aprepitant, and olanzapine for a cisplatin-containing regimen. - PATROL-I
2023
Yokokawa T, Suzuki K, Tsuji D, Hosonaga M, Kobayashi K, Kawakami K, Kawazoe H, Nakamura T, Suzuki W, Sugisaki T, Aoyama T, Hashimoto K, Hatori M, Tomomatsu T, Inoue A, Azuma K, Asano M, Takano T, Ohno S, Yamaguchi M.
Influence of menopause on chemotherapy-induced nausea and vomiting in highly emetogenic chemotherapy for breast cancer: A retrospective observational study
Chemotherapy-induced neutropenia as a prognostic factor in patients with extensive-stage small cell lung cancer
Influence of menopause on chemotherapy-induced nausea and vomiting in highly emetogenic chemotherapy for breast cancer: A retrospective observational study
Cancer Med. 12:18745-18754 (2023)
Miyagi T, Tsuji D, Kawasakai Y, Ishikawa H, Tanaka R, Nakao M, Nakagaki S, Hayashi T, Ayuhara H, Harada T, Tamaki S, Maeda A, Ohashi Y, Arakawa Y, Fujita Y, Yamamoto K, Miyamoto Y, Yano T, Itoh K.Chemotherapy-induced neutropenia as a prognostic factor in patients with extensive-stage small cell lung cancer
2022
Nomura H, Tsuji D, Ueno S, Kojima T, Fujii S, Yano T, Daiko H, Demachi K, Itoh K, Kawasaki T.
Relevance of pharmacogenetic polymorphisms with response to docetaxel, cisplatin, and 5-fluorouracil chemotherapy in esophageal cancer
Mucus Plugs and Small Airway Dysfunction in Asthma, COPD, and Asthma-COPD Overlap
Forced oscillatory parameters as predictors of COPD assessment test improvement in untreated COPD patients
Blood eosinophil count and FeNO to predict benralizumab effectiveness in real-life severe asthma patients
Relevance of pharmacogenetic polymorphisms with response to docetaxel, cisplatin, and 5-fluorouracil chemotherapy in esophageal cancer
Invest New Drugs. 40:420-429 (2022)
Tamura K, Shirai T, Hirai K, Nakayasu H, Takahashi S, Kishimoto Y, Akamatsu T, Asada K, Kato S.Mucus Plugs and Small Airway Dysfunction in Asthma, COPD, and Asthma-COPD Overlap
Allergy Asthma Immunol Res. 14:196-209 (2022)
Takahashi S, Shirai T, Hirai K, Akamatsu T.Forced oscillatory parameters as predictors of COPD assessment test improvement in untreated COPD patients
Respir Physiol Neurobiol. 296:103809 (2022)
Watanabe H, Shirai T, Hirai K, Akamatsu T, Nakayasu H, Tamura K, Masuda T, Takahashi S, Tanaka Y, Kishimoto Y, Oishi K, Saigusa M, Yamamoto A, Morita S, Asada K.Blood eosinophil count and FeNO to predict benralizumab effectiveness in real-life severe asthma patients
2021
Hirai K, Uehara S, Shirai T, Rachi Y, Kimura T, Akamatsu T, Itoh K.
Benralizumab restores gene and microRNA expression involved in steroid sensitivity in severe asthma Tsuji D, Saito Y, Mushiroda T, Miura M, Hira D, Terada T.
Results of a nationwide survey of Japanese pharmacists regarding the application of pharmacogenomic testing in precision medicine
Circulating microRNA‐15b‐5p as a biomarker for asthma‐COPD overlap Suzuki K, Naito T, Tanaka H, Shibata K, Yamada Y, Itoh K, Kawakami J.
Impact of CYP2D6 activity and cachexia progression on enantiomeric alteration of plasma tramadol and its demethylated metabolites and their relationships with central nervous system symptoms in head and neck cancer patients
Analysis of pharmacogenomic factors for chemotherapy-induced nausea and vomiting in patients with breast cancer receiving doxorubicin and cyclophosphamide chemotherapy
High fractional exhaled nitric oxide levels may predict short-term worsening of respiratory oscillometry in asthma Shirai T, Hirai K, Gon Y, Maruoka S, Mizumura K, Hikichi M, Itoh K, Hashimoto S.
Combined assessment of serum eosinophil-derived neurotoxin and YKL-40 may identify Asthma-COPD overlap
Benralizumab restores gene and microRNA expression involved in steroid sensitivity in severe asthma Tsuji D, Saito Y, Mushiroda T, Miura M, Hira D, Terada T.
Results of a nationwide survey of Japanese pharmacists regarding the application of pharmacogenomic testing in precision medicine
J Clin Pharm Ther. 46:649-657 (2021)
Hirai K, Shirai T, Shimoshikiryo T, Ueda M, Gon Y, Maruoka S, Itoh K.Circulating microRNA‐15b‐5p as a biomarker for asthma‐COPD overlap Suzuki K, Naito T, Tanaka H, Shibata K, Yamada Y, Itoh K, Kawakami J.
Impact of CYP2D6 activity and cachexia progression on enantiomeric alteration of plasma tramadol and its demethylated metabolites and their relationships with central nervous system symptoms in head and neck cancer patients
Basic Clin Pharmacol Toxicol. 128:472-481 (2021)
Tsuji D, Matsumoto M, Kawasaki Y, Kim YL, Yamamoto K, Nakamichi H, Sahara Y, Makuta R, Yokoi M, Miyagi T, Itoh K.Analysis of pharmacogenomic factors for chemotherapy-induced nausea and vomiting in patients with breast cancer receiving doxorubicin and cyclophosphamide chemotherapy
Cancer Chemother Pharmacol. 87:73-83 (2021)
Endo Y, Shirai T, Hirai K, Akamatsu T, Kato E, Furui H, Hiramatsu T.High fractional exhaled nitric oxide levels may predict short-term worsening of respiratory oscillometry in asthma Shirai T, Hirai K, Gon Y, Maruoka S, Mizumura K, Hikichi M, Itoh K, Hashimoto S.
Combined assessment of serum eosinophil-derived neurotoxin and YKL-40 may identify Asthma-COPD overlap
2020
Yamamoto A, Shirai T, Hirai K, Tanaka Y, Watanabe H, Endo Y, Shimoda Y, Suzuki T, Noguchi R, Mochizuki E, Sakurai S, Saigusa M, Akamatsu T, Shishido Y, Akita T, Morita S, Asada K.
Oscillometry as a Predictor of Exercise Tolerance in COPD Nishida S, Hayashi Y, Hirai K, Takekoshi A, Yamada Y, Kobayashi R, Shimizu S, Niwa T, Hayashi H, Shimohata T, Sugiyama T, Suzuki A.
Effect of therapeutic plasma exchange on phenytoin plasma concentration in patients receiving intravenous fosphenytoin therapy Oishi K, Matsunaga K, Shirai T, Hirai K, Gon Y.
Role of Type2 Inflammatory Biomarkers in Chronic Obstructive Pulmonary Disease Nomura H, Tsuji D, Demachi K, Mochizuki N, Matsuzawa H, Yano T, Daiko H, Fujii S, Kojima T, Itoh K, Kawasaki T.
ABCB1 and ABCC2 genetic polymorphism as risk factors for neutropenia in esophageal cancer patients treated with docetaxel cisplatin and 5-fluorouracil chemotherapy
Annual changes in forced oscillation technique parameters correlate with FEV1 decline in patients with asthma, COPD, and asthma-COPD overlap
Oscillometry improves earlier than spirometry after benralizumab initiation in severe asthma Eliasen A, Dalhoff K, Mathiasen R, Schmiegelow K, Rechnitzer C, Schelde AB, Perwitasari DA, Tsuji D, Brok J.
Pharmacogenetics of antiemetics for chemotherapy-induced nausea and vomiting: A systematic review and meta-analysis
薬学的視点に基づいたプレシジョン・メディシンの国内基盤構築のための調査研究
CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin maintenance dose: a systematic review and meta-analysis
A reversed-phase mode LC-MS/MS method using a polysaccharide chiral selector for simultaneous quantitation of each enantiomer of tramadol and its metabolites in human plasma and evaluation of CYP-mediated stereoselective demethylation
Oscillometry as a Predictor of Exercise Tolerance in COPD Nishida S, Hayashi Y, Hirai K, Takekoshi A, Yamada Y, Kobayashi R, Shimizu S, Niwa T, Hayashi H, Shimohata T, Sugiyama T, Suzuki A.
Effect of therapeutic plasma exchange on phenytoin plasma concentration in patients receiving intravenous fosphenytoin therapy Oishi K, Matsunaga K, Shirai T, Hirai K, Gon Y.
Role of Type2 Inflammatory Biomarkers in Chronic Obstructive Pulmonary Disease Nomura H, Tsuji D, Demachi K, Mochizuki N, Matsuzawa H, Yano T, Daiko H, Fujii S, Kojima T, Itoh K, Kawasaki T.
ABCB1 and ABCC2 genetic polymorphism as risk factors for neutropenia in esophageal cancer patients treated with docetaxel cisplatin and 5-fluorouracil chemotherapy
Cancer Chemother Pharmacol. 86:315-324 (2020)
Tanaka Y, Hirai K, Nakayasu H, Tamura K, Masuda T, Takahashi S, Watanabe H, Kishimoto Y, Ohishi K, Saigusa M, Akamatsu T, Yamamoto A, Morita S, Asada K, Shirai T.Annual changes in forced oscillation technique parameters correlate with FEV1 decline in patients with asthma, COPD, and asthma-COPD overlap
Allergol Int. 69:626-627 (2020)
Shirai T, Akamatsu T, Hirai K, Watanabe H, Tamura K, Kishimoto Y, Saigusa M.Oscillometry improves earlier than spirometry after benralizumab initiation in severe asthma Eliasen A, Dalhoff K, Mathiasen R, Schmiegelow K, Rechnitzer C, Schelde AB, Perwitasari DA, Tsuji D, Brok J.
Pharmacogenetics of antiemetics for chemotherapy-induced nausea and vomiting: A systematic review and meta-analysis
Crit Rev Oncol Hematol. 149:102939 (2020)
辻 大樹, 齋藤嘉朗, 莚田泰誠, 三浦昌朋, 平 大樹, 寺田智祐.薬学的視点に基づいたプレシジョン・メディシンの国内基盤構築のための調査研究
医療薬学. 46:66-76 (2020)
Takeuchi M, Kobayashi T, Biss T, Kamali F, Vear SI, Ho RH, Bajolle F, Loriot MA, Shaw K, Carleton BC, Hamberg AK, Wadelius M, Hirono K, Taguchi M, Wakamiya T, Yanagimachi M, Hirai K, Itoh K, Brandao LR, Ito S.CYP2C9, VKORC1, and CYP4F2 polymorphisms and pediatric warfarin maintenance dose: a systematic review and meta-analysis
Pharmacogenomics J. 20:306-319 (2020)
Suzuki K, Naito T, Tanaka H, Yamada Y, Itoh K, Kawakami J.A reversed-phase mode LC-MS/MS method using a polysaccharide chiral selector for simultaneous quantitation of each enantiomer of tramadol and its metabolites in human plasma and evaluation of CYP-mediated stereoselective demethylation
2019
Hirai K, Shirai T, Suzuki Y, Shimomura T, Itoh K.
Comparison of the association between circulating vitamin D3 levels and clinical outcomes in patients with asthma and chronic obstructive pulmonary disease: a prospective observational study
Impact of gene expression associated with glucocorticoid-induced transcript 1 (GLCCI1) on severe asthma and future exacerbation
Forced Oscillation Technique May Identify Severe Asthma
Anti-Idiotype DNA Aptamer Affinity Purification High-Temperature Reversed-Phase Liquid Chromatography: A Simple, Accurate, and Selective Bioanalysis of Bevacizumab Yamamoto K, Sasano T, Tsuji D, Ishizuka Y, Tokou U, Nakamichi H, Yoneda T, Shiokawa M, Yabe K.
A Retrospective Analysis of the Effects of Chemotherapy-Induced Neutropenia on Overall Survival in Patients With Unresectable or Metastatic Urothelial Carcinoma to Gemcitabine Plus Cisplatin Combination Chemotherapy
Forced oscillation technique may identify asthma-COPD overlap
Improved cough- and sputum-related quality of life after initiation of treatment in pulmonary tuberculosis
Risk factors associated with chemotherapy-induced nausea and vomiting in the triplet antiemetic regimen including palonosetron or granisetron for cisplatin-based chemotherapy: analysis of a randomized, double-blind controlled trial
Forced oscillatory parameters in reversibility testing as predictors for chronic cough responsive to inhaled corticosteroid/long-acting β2 agonist
Combined assessment of serum periostin and YKL-40 may identify asthma-COPD overlap
The effect of CYP4F2, VKORC1 and CYP2C9 in influencing coumarin dose. A single patient data meta-analysis in more than 15,000 individuals
平井 啓太, 白井 敏博, 伊藤 邦彦.
成人喘息患者における増悪発現予測バイオマーカー 平井 啓太.
ゲノム薬理と薬物動態解析を基盤とした薬物療法及び病態の個別化研究
Comparison of the association between circulating vitamin D3 levels and clinical outcomes in patients with asthma and chronic obstructive pulmonary disease: a prospective observational study
Biol Pharm Bull. 42:1861-1866 (2019)
Hirai K, Shirai T, Rachi Y, Uehara S, Ueda M, Nakatani E, Itoh K.Impact of gene expression associated with glucocorticoid-induced transcript 1 (GLCCI1) on severe asthma and future exacerbation
Biol Pharm Bull. 42:1746-1752 (2019)
Shirai T, Hirai K, Gon Y, Maruoka S, Mizumura K, Hikichi M, Itoh K, Hashimoto S.Forced Oscillation Technique May Identify Severe Asthma
J Allergy Clin Immunol Pract. 7:2857-2860 (2019)
Yamada T, Saito T, Shimizu Y, Tsukakoshi K, Hayashi H, Mizuno H, Tsuji D, Yamamoto K, Itoh K, Toyo'oka T, Ikebukuro K, Todoroki K.Anti-Idiotype DNA Aptamer Affinity Purification High-Temperature Reversed-Phase Liquid Chromatography: A Simple, Accurate, and Selective Bioanalysis of Bevacizumab Yamamoto K, Sasano T, Tsuji D, Ishizuka Y, Tokou U, Nakamichi H, Yoneda T, Shiokawa M, Yabe K.
A Retrospective Analysis of the Effects of Chemotherapy-Induced Neutropenia on Overall Survival in Patients With Unresectable or Metastatic Urothelial Carcinoma to Gemcitabine Plus Cisplatin Combination Chemotherapy
Ann Pharmacother. 53:690-696 (2019)
Shirai T, Hirai K, Gon Y, Maruoka S, Mizumura K, Hikichi M, Itoh K, Hashimoto S.Forced oscillation technique may identify asthma-COPD overlap
Allergol Int. 68:385-387 (2019)
Suzuki T, Shirai T, Hirai K, Tanaka Y, Watanabe H, Endo Y, Shimoda Y, Saigusa M, Akamatsu T, Yamamoto A, Morita S, Asada K.Improved cough- and sputum-related quality of life after initiation of treatment in pulmonary tuberculosis
Respir Investig. 57:252-259 (2019)
Tsuji D, Suzuki K, Kawasaki Y, Goto K, Matsui R, Seki N, Hashimoto H, Hama T, Yamanaka T, Yamamoto N, Itoh K.Risk factors associated with chemotherapy-induced nausea and vomiting in the triplet antiemetic regimen including palonosetron or granisetron for cisplatin-based chemotherapy: analysis of a randomized, double-blind controlled trial
Support Care Cancer. 27:1139-1147 (2019)
Watanabe H, Shirai T, Akamatsu T, Asada K, Hirai K.Forced oscillatory parameters in reversibility testing as predictors for chronic cough responsive to inhaled corticosteroid/long-acting β2 agonist
Ann Allergy Asthma Immunol. 122:345-346 (2019)
Shirai T, Hirai K, Gon Y, Maruoka S, Mizumura K, Hikichi M, Holweg C, Itoh K, Inoue H, Hashimoto S.Combined assessment of serum periostin and YKL-40 may identify asthma-COPD overlap
J Allergy Clin Immunol Pract. 7:134-145.e1 (2019)
Danese E, Raimondi S, Montagnana M, Tagetti A, Langaee T, Borgiani P, Ciccacci C, Carcas AJ, Borobia AM, Tong HY, Davila-Fajardo C, Botton MR, Bourgeois S, Deloukas P, Caldwell MD, Burmester JK, Berg RL, Cavallari LH, Drozda K, Huang M, Zhao LZ, Cen HJ, Gonzalez-Conejero R, Roldan V, Nakamura Y, Mushiroda T, Gong IY, Kim RB, Hirai K, Itoh K, Isaza C, Beltran L, Jimenez-Varo E, Canadas-Garre M, Giontella A, Kringen MK, Bente Foss Haug K, Gwak HS, Lee KE, Minuz P, Lee MTM, Lubitz SA, Scott S, Mazzaccara C, Sacchetti L, Genc E, Ozer M, Pathare A, Krishnamoorthy R, Paldi A, Siguret V, Loriot MA, Kutala VK, Suarez-Kurtz G, Perini J, Denny JC, Ramirez AH, Mittal B, Rathore SS, Sagreiya H, Altman R, Shahin MHA, Khalifa SI, Limdi NA, Rivers C, Shendre A, Dillon C, Suriapranata IM, Zhou HH, Tan SL, Tatarunas V, Lesauskaite V, Zhang Y, Maitland-van der Zee AH, Verhoef TI, de Boer A, Taljaard M, Zambon CF, Pengo V, Zhang JE, Pirmohamed M, Johnson JA, Fava C.The effect of CYP4F2, VKORC1 and CYP2C9 in influencing coumarin dose. A single patient data meta-analysis in more than 15,000 individuals
Clin Pharmacol Ther. 105:1477-1491 (2019)
総説平井 啓太, 白井 敏博, 伊藤 邦彦.
成人喘息患者における増悪発現予測バイオマーカー 平井 啓太.
ゲノム薬理と薬物動態解析を基盤とした薬物療法及び病態の個別化研究
2018
Shimizu H, Suzuki K, Uchikura T, Tsuji D, Yamanaka T, Hashimoto H, Goto K, Matsui R, Seki N, Shimada T, Ikeda S, Ikegami N, Hama T, Yamamoto N, Sasaki T.
Economic analysis of palonosetron versus granisetron in the standard triplet regimen for preventing chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy in Japan (TRIPLE phase III trial)
Validation of a nomogram for achieving target trough concentration of vancomycin: accuracy in patients with augmented renal function
Time-Dependent Decline in Serum Phenytoin Concentration with Heightened Convulsive Seizure Risk by Prolonged Administration of Fosphenytoin in Japanese: A Retrospective Study
Association between (CCTTT)n repeat polymorphism in NOS2 promoter and asthma exacerbations
Genetic risk factors for chemotherapy-induced nausea and vomiting in patients with cancer receiving cisplatin-based chemotherapy
Human recombinant Fab fragment from combinatorial libraries of a B-cell lymphoma patient recognizes core protein of chondroitin sulfate proteoglycan 4
Economic analysis of palonosetron versus granisetron in the standard triplet regimen for preventing chemotherapy-induced nausea and vomiting in patients receiving highly emetogenic chemotherapy in Japan (TRIPLE phase III trial)
J Pharm Health Care Sci. 4:31 (2018)
Ishii H, Hirai K, Sugiyama K, Nakatani E, Kimura M, Itoh K.Validation of a nomogram for achieving target trough concentration of vancomycin: accuracy in patients with augmented renal function
Ther Drug Monit. 40:693-698 (2018)
Ohno Y, Niwa T, Hirai K, Suzuki K, Yamada Y, Hayashi Y, Hayashi H, Suzuki A, Itoh Y.Time-Dependent Decline in Serum Phenytoin Concentration with Heightened Convulsive Seizure Risk by Prolonged Administration of Fosphenytoin in Japanese: A Retrospective Study
Ther Drug Monit. 40:507-511 (2018)
Hirai K, Shirai T, Suzuki M, Shimomura T, Itoh K.Association between (CCTTT)n repeat polymorphism in NOS2 promoter and asthma exacerbations
J Allergy Clin Immunol. 142:663-665.e3 (2018)
Yokoi M, Tsuji D, Suzuki K, Kawasaki Y, Nakao M, Ayuhara H, Kogure Y, Shibata K, Hayashi T, Hirai K, Inoue K, Hama T, Takeda K, Nishio M, Itoh K.Genetic risk factors for chemotherapy-induced nausea and vomiting in patients with cancer receiving cisplatin-based chemotherapy
Support Care Cancer. 26:1505-1513 (2018)
Egami Y, Narushima Y, Ohshima M, Yoshida A, Yoneta N, Masaki Y, Itoh K.Human recombinant Fab fragment from combinatorial libraries of a B-cell lymphoma patient recognizes core protein of chondroitin sulfate proteoglycan 4
2017
Hirai K, Shirai T, Suzuki M, Akamatsu T, Suzuki T, Hayashi I, Yamamoto A, Akita T, Morita S, Asada K, Tsuji D, Inoue K, Itoh K.
A clustering approach to identify and characterize the asthma and chronic obstructive pulmonary disease overlap phenotype
Chemotherapy-induced neutropenia as a prognostic factor in patients with metastatic pancreatic cancer treated with gemcitabine
Influence of ABCB1 and ABCG2 polymorphisms on the antiemetic efficacy in patients with cancer receiving cisplatin-based chemotherapy: a TRIPLE pharmacogenomics study
ドキソルビシン／シクロホスファミド併用療法施行乳がん患者における化学療法誘発性悪心・嘔吐に対するアプレピタントの効果の検討
A clustering approach to identify and characterize the asthma and chronic obstructive pulmonary disease overlap phenotype
Clin Exp Allergy. 47:1374-1382 (2017)
Otake A, Tsuji D, Taku K, Kawasaki Y, Yokoi M, Nakamori H, Osada M, Matsumoto M, Inoue K, Hirai K, Itoh K.Chemotherapy-induced neutropenia as a prognostic factor in patients with metastatic pancreatic cancer treated with gemcitabine
Eur J Clin Pharmacol. 73:1033-1039 (2017)
Tsuji D, Yokoi M, Suzuki K, Daimon T, Nakao M, Ayuhara H, Kogure Y, Shibata K, Hayashi T, Hirai K, Inoue K, Hama T, Takeda K, Nishio M, Itoh K.Influence of ABCB1 and ABCG2 polymorphisms on the antiemetic efficacy in patients with cancer receiving cisplatin-based chemotherapy: a TRIPLE pharmacogenomics study
Pharmacogenomics J. 17:435-440 (2017)
幕田 龍，辻 大樹，金 容壱，山本圭祐，大嶽亜季，横井茉里，中森春美，井上和幸，平井啓太，中道秀徳，塩川 満，伊藤邦彦.ドキソルビシン／シクロホスファミド併用療法施行乳がん患者における化学療法誘発性悪心・嘔吐に対するアプレピタントの効果の検討
2016
Tsuji D, Ikeda M, Yamamoto K, Nakamori H, Kim Y, Kawasaki Y, Otaki A, Yokoi M, Inoue K, Hirai K, Nakamichi H, Tokou U, Shiokawa M, Itoh K.
Drug-related genetic polymorphisms affecting severe chemotherapy-induced neutropenia in breast cancer patients: A hospital-based observational study Hirai K, Ishii H, Shimoshikiryo T, Shimomura T, Tsuji D, Inoue K, Kadoiri T, Itoh K.
Augmented renal clearance in patients with febrile neutropenia is associated with increased risk for subtherapeutic concentrations of vancomycin
Risk factors for hypernatremia in patients with short- and long-term tolvaptan treatment
Influence of genetic polymorphisms and concomitant anxiolytic doses on antidepressant maintenance doses in Japanese patients with depression
Bioanalysis of bevacizumab and infliximab by high-temperature reversed-phase liquid chromatography with fluorescence detection after immunoaffinity magnetic purification
Factors that influence the pharmacokinetics of lamotrigine in Japanese patients with epilepsy
Augmented renal clearance in pediatric patients with febrile neutropenia associated with vancomycin clearance
リファンピシンとアムロジピンの薬物間相互作用に関する後向き観察研究
Drug-related genetic polymorphisms affecting severe chemotherapy-induced neutropenia in breast cancer patients: A hospital-based observational study Hirai K, Ishii H, Shimoshikiryo T, Shimomura T, Tsuji D, Inoue K, Kadoiri T, Itoh K.
Augmented renal clearance in patients with febrile neutropenia is associated with increased risk for subtherapeutic concentrations of vancomycin
Ther Drug Monit. 38:706-710 (2016)
Hirai K, Shimomura T, Moriwaki H, Ishii H, Shimoshikiryo T, Tsuji D, Inoue K, Kadoiri T, Itoh K.Risk factors for hypernatremia in patients with short- and long-term tolvaptan treatment
Eur J Clin Pharmacol. 72:1177-1183 (2016)
Inoue K, Murofushi T, Nagaoka K, Ando N, Hakamata Y, Suzuki A, Umemura A, Yoshida Y, Hirai K, Tsuji D, Itoh K.Influence of genetic polymorphisms and concomitant anxiolytic doses on antidepressant maintenance doses in Japanese patients with depression
Biol Pharm Bull. 39:1508-1513 (2016)
Todoroki K, Nakano T, Eda Y, Ohyama K, Hayashi H, Tsuji D, Min JZ, Inoue K, Iwamoto N, Kawakami A, Ueki Y, Itoh K, Toyo'oka T.Bioanalysis of bevacizumab and infliximab by high-temperature reversed-phase liquid chromatography with fluorescence detection after immunoaffinity magnetic purification
Anal Chim Acta. 916:112-119 (2016)
Inoue K, Yamamoto Y, Suzuki E, Takahashi T, Umemura A, Takahashi Y, Imai K, Inoue Y, Hirai K, Tsuji D, Itoh K.Factors that influence the pharmacokinetics of lamotrigine in Japanese patients with epilepsy
Eur J Clin Pharmacol. 72:555-562 (2016)
Hirai K, Ihara S, Kinae A, Ikegaya K, Suzuki M, Hirano K, Itoh K.Augmented renal clearance in pediatric patients with febrile neutropenia associated with vancomycin clearance
Ther Drug Monit. 38:393-397 (2016)
櫻井健史, 平井啓太, 杉山慎一, 石井英俊, 伊藤邦彦, 角入壽彦.リファンピシンとアムロジピンの薬物間相互作用に関する後向き観察研究
日本病院薬剤師会雑誌. 52:63-66 (2016)
2015
Mishima E, Jinno D, Akiyama Y, Itoh K, Nankumo S, Shima H, Kikuchi K, Takeuchi Y, Elkordy A, Suzuki T, Niizuma K, Ito S, Tomioka Y, Abe T.
Immuno-Northern Blotting: Detection of RNA Modifications by Using Antibodies against Modified Nucleosides Inoue K, Takahashi T, Yamamoto Y, Suzuki E, Takahashi Y, Imai K, Inoue Y, Hirai K, Tsuji D, Itoh K.
Influence of glutamine synthetase gene polymorphisms on the development of hyperammonemia during valproic acid-based therapy Hirai K, Yamada Y, Hayashi H, Tanaka M, Izumiya K, Suzuki M, Yoshizawa M, Moriwaki H, Akimoto T, Tsuji D, Inoue K, Itoh K.
Plasma vitamin K concentrations depend on CYP4F2 polymorphism and influence on anticoagulation in Japanese patients with warfarin therapy
Reduced folate carrier 1 gene expression levels are correlated with methotrexate efficacy in Japanese patients with rheumatoid arthritis
Relationship between ABCB1 gene polymorphisms and severe neutropenia in patients with breast cancer treated with doxorubicin/cyclophosphamide chemotherapy
Immuno-Northern Blotting: Detection of RNA Modifications by Using Antibodies against Modified Nucleosides Inoue K, Takahashi T, Yamamoto Y, Suzuki E, Takahashi Y, Imai K, Inoue Y, Hirai K, Tsuji D, Itoh K.
Influence of glutamine synthetase gene polymorphisms on the development of hyperammonemia during valproic acid-based therapy Hirai K, Yamada Y, Hayashi H, Tanaka M, Izumiya K, Suzuki M, Yoshizawa M, Moriwaki H, Akimoto T, Tsuji D, Inoue K, Itoh K.
Plasma vitamin K concentrations depend on CYP4F2 polymorphism and influence on anticoagulation in Japanese patients with warfarin therapy
Thromb Res, 135, 861-866 (2015)
Tazoe Y, Hayashi H, Tsuboi S, Shioura T, Matsuyama T, Yamada H, Hirai K, Tsuji D, Inoue K, Sugiyama T, Itoh K.Reduced folate carrier 1 gene expression levels are correlated with methotrexate efficacy in Japanese patients with rheumatoid arthritis
Drug Metab Pharmacokinet. 30, 227-230 (2015)
Ikeda M, Tsuji D, Yamamoto K, Kim Y, Daimon T, Iwabe Y, Hatori M, Makuta R, Hayashi H, Inoue K, Nakamichi H, Shiokawa M, Itoh K.Relationship between ABCB1 gene polymorphisms and severe neutropenia in patients with breast cancer treated with doxorubicin/cyclophosphamide chemotherapy
2014
羽鳥正浩，辻 大樹，多久佳成，大門貴志，亀里真那，池田 翠，幕田 龍，林 秀樹，井上和幸，伊藤邦彦.
ゲムシタビン施行切除不能膵がん患者における予後因子の検討 Tsuji D, Kamezato M, Daimon T, Taku K, Hatori M, Ikeda M, Hayashi H, Inoue K, Eto T, Itoh K.
Retrospective Analysis of Severe Neutropenia in Patients Receiving Concomitant Administration of Docetaxel and Clarithromycin
4217C>A polymorphism in carbamoyl-phosphate synthase 1 gene may not associate with hyperammonemia development during valproic acid-based therapy
Conformational Change in Transfer RNA Is an Early Indicator of Acute Cellular Damage
Endothelin-1 Receptors in Rat Tissues: Characterization by Bosentan, Ambrisentan and CI-1020
Identification of anti-CD98 antibody mimotopes for inducing antibodies with antitumor activity by mimotope immunization
Bladder Endothelin-1 Receptor Binding of Bosentan and Ambrisentan
Influence of Uridine Diphosphate Glucuronosyltransferase 2B7 -161C>T Polymorphism on the Concentration of Valproic Acid in Pediatric Epilepsy Patients
Simultaneous microdetermination of bosentan, ambrisentan, sildenafil, and tadalafil in plasma using liquid chromatography/tandem mass spectrometry for pediatric patients with pulmonary arterial hypertension
ゲムシタビン施行切除不能膵がん患者における予後因子の検討 Tsuji D, Kamezato M, Daimon T, Taku K, Hatori M, Ikeda M, Hayashi H, Inoue K, Eto T, Itoh K.
Retrospective Analysis of Severe Neutropenia in Patients Receiving Concomitant Administration of Docetaxel and Clarithromycin
Chemotherapy, 59, 407-413 (2013)
Inoue K, Suzuki E, Takahashi T, Yamamoto Y, Yazawa R, Imai K, Miyakawa K, Inoue Y, Tuji D, Hayashi H, Itoh K.4217C>A polymorphism in carbamoyl-phosphate synthase 1 gene may not associate with hyperammonemia development during valproic acid-based therapy
Epilepsy Res., 108, 1046-1051 (2014)
Mishima E, Inoue C, Saigusa D, Inoue R, Ito K, Suzuki Y, Jinno D, Tsukui Y, Akamatsu Y, Araki M, Araki K, Shimizu R, Shinke H, Suzuki T, Takeuchi Y, Shima H, Akiyama Y, Toyohara T, Suzuki C, Saiki Y, Tominaga T, Miyagi S, Kawagisihi N10, Soga T, Ohkubo T, Yamamura K, Imai Y1, Masuda S, Sabbisetti V, Ichimura T, Mount DB, Bonventre JV, Ito S, Tomioka Y, Itoh K, Abe T.Conformational Change in Transfer RNA Is an Early Indicator of Acute Cellular Damage
J Am Soc Nephrol., 25, 2316-2326 (2014)
Yokoyama Y, Osano A, Hayashi H, Itoh K, Okura T, Deguchi Y, Ito Y, Yamada SEndothelin-1 Receptors in Rat Tissues: Characterization by Bosentan, Ambrisentan and CI-1020
Biol. Pharm. Bull., 37, 461-4651 (2014)
Saito M, Kondo M, Ohshima M, Deguchi K, Hayashi H, Inoue K, Tsuji D, Masuko T, Itoh K.Identification of anti-CD98 antibody mimotopes for inducing antibodies with antitumor activity by mimotope immunization
Cancer Sci., 105, 396-401 (2014)
Osano A, Yokoyama Y, Hayashi H, Itoh K, Okura T, Deguchi Y, Ito Y, Yamada S.Bladder Endothelin-1 Receptor Binding of Bosentan and Ambrisentan
J. Pharmacol. Sci., 124, 86-91 (2014)
Inoue K, Suzuki E, Yazawa R, Yamamoto Y, Takahashi T, Takahashi Y, Imai K, Koyama S, Inoue Y, Tsuji D, Hayashi H, Itoh K.Influence of Uridine Diphosphate Glucuronosyltransferase 2B7 -161C>T Polymorphism on the Concentration of Valproic Acid in Pediatric Epilepsy Patients
Ther. Drug Monit.,36, 406-409 (2014)
Yokoyama Y, Tomatsuri M, Hayashi H, Hirai K, Ono Y, Yamada Y, Todoroki K, Toyo'oka T, Yamada H, Itoh K.Simultaneous microdetermination of bosentan, ambrisentan, sildenafil, and tadalafil in plasma using liquid chromatography/tandem mass spectrometry for pediatric patients with pulmonary arterial hypertension
2013
大島幹弘，中村安孝，池田直人，西山博隆，小菅和仁，山田 浩，伊藤邦彦，松山耐至
バラつきの少ない錠剤分割法の検討
Association of ABCB1 polymorphisms with the antiemetic efficacy of granisetron plus dexamethasone in breast cancer patients
リウマチ患者における生物学的製剤投与時の併用薬への影響 Hayashi H, Tazoe Y, Tsuboi S, Horino M, Morishita M, Arai T, Ohshima M, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh K.
A single nucleotide polymorphism of reduced folate carrier 1 predicts methotrexate efficacy in Japanese patients with rheumatoid arthritis
Influence of CYP4F2 polymorphisms and plasma vitamin K levels on warfarin sensitivity in Japanese pediatric patients
Characterization of the carrier-mediated transport of ketoprofen, a nonsteroidal anti-inflammatory drug, in rabbit corneal epithelium cells
Risk factors for hyperammonemia in pediatric patients with epilepsy Inoue K, Sonobe M, Kawamura Y, Etoh T, Takagi M, Matsumura T, Kikuyama M, Kimura M, Minami S, Utsuki H, Yamazaki T, Suzuki T, Tsuji D, Hayashi H, Itoh K.
Polymorphisms of the UDP-glucuronosyl transferase 1A genes are associated with adverse events in cancer patients receiving irinotecan-based chemotherapy
遺伝子多型と薬物動態解析に基づく個別化薬物療法を目指した臨床薬理研究 辻 大樹
がん領域の医薬品情報：ゲムシタビン
５．副作用発現に影響をおよぼす因子 Ⅱ個人的素因（トキシコゲノミクス）
バラつきの少ない錠剤分割法の検討
医療薬学, 39, 499-503 (2013)
Tsuji D, Kim YI, Nakamichi H, Daimon T, Suwa K, Iwabe Y, Hayashi H, Inoue K, Yoshida M, Itoh K.Association of ABCB1 polymorphisms with the antiemetic efficacy of granisetron plus dexamethasone in breast cancer patients
Drug Metab. Pharmacokinrt. 28, 299-304 (2013)
大島幹弘，西山博隆，坪井声示，塩浦朋根，林 秀樹，伊藤邦彦，松山耐至リウマチ患者における生物学的製剤投与時の併用薬への影響 Hayashi H, Tazoe Y, Tsuboi S, Horino M, Morishita M, Arai T, Ohshima M, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh K.
A single nucleotide polymorphism of reduced folate carrier 1 predicts methotrexate efficacy in Japanese patients with rheumatoid arthritis
Drug Metab. Pharmacokinrt., 28, 164-168 (2013)
Hirai K, Hayashi H, Ono Y, Izumiya K, Tanaka M, Suzuki T, Sakamoto T, Itoh K.Influence of CYP4F2 polymorphisms and plasma vitamin K levels on warfarin sensitivity in Japanese pediatric patients
Drug Metab. Pharmacokinrt., 28, 132-137 (2013)
Fujii S, Hayashi H, Itoh K, Yamada S, Deguchi Y, Kawazu K.Characterization of the carrier-mediated transport of ketoprofen, a nonsteroidal anti-inflammatory drug, in rabbit corneal epithelium cells
J. Pharm. Pharmacol., 65, 171-180 (2013)
Yamamoto Y, Takahashi Y, Imai K, Mishima N, Yazawa R, Inoue K, Itoh K, Kagawa Y, Inoue Y.Risk factors for hyperammonemia in pediatric patients with epilepsy Inoue K, Sonobe M, Kawamura Y, Etoh T, Takagi M, Matsumura T, Kikuyama M, Kimura M, Minami S, Utsuki H, Yamazaki T, Suzuki T, Tsuji D, Hayashi H, Itoh K.
Polymorphisms of the UDP-glucuronosyl transferase 1A genes are associated with adverse events in cancer patients receiving irinotecan-based chemotherapy
Tohoku J. Exp. Med., 229, 107-114 (2013)
林 秀樹遺伝子多型と薬物動態解析に基づく個別化薬物療法を目指した臨床薬理研究 辻 大樹
がん領域の医薬品情報：ゲムシタビン
J. Oncol. Pharm., 5, 3-6 (2013)
伊藤邦彦５．副作用発現に影響をおよぼす因子 Ⅱ個人的素因（トキシコゲノミクス）
図解 薬害・副作用学（南山堂）, 122-127 (2013)
2012
Nakamichi H, Fujita T, Tsuji D, Atsumi I, Totsuka K, Suzuki R, Miki Y, Tomita K, Nakamura H, Shiokawa M.
Analysis of risk factors of drug-induced lung injury in patients receiving gemcitabine treatment
Risk factors for hyperammonemia associated with valproic acid therapy in adult epilepsy patients
エタネルセプト25mg皮下注シリンジ週2回投与から50mg皮下注シリンジ週1回投与に変更した患者における有用性の評価 Inoue K, Ando N, Suzuki E, Hayashi H, Tsuji D, Itoh K.
Genotype distributions and allele frequencies of possible major depressive disorder-associated single nucleotide polymorphisms, cyclic adenosine monophosphate response element binding protein 1 rs4675690 and Piccolo rs2522833, in a Japanese population
Comparative trial of two intravenous doses of granisetron (1 versus 3 mg) in the prevention of chemotherapy-induced acute emesis: a double-blind, randomized, non-inferiority trial
An artifact derived from pseudogene led to the discovery of micro RNA binding site polymorphism in 3′-untranslated region of human dihydrofolate reductase gene
臨床薬学演習のコンテンツ作成における大学連携のメリット
Analysis of risk factors of drug-induced lung injury in patients receiving gemcitabine treatment
Gan To Kagaku Ryoho, 39, 787-792 (2012)
Yamamoto Y, Takahashi Y, Suzuki E, Mishima N, Inoue K, Itoh K, Kagawa Y, Inoue Y.Risk factors for hyperammonemia associated with valproic acid therapy in adult epilepsy patients
Epilepsy Res., 101, 202-9 (2012)
大島幹弘、中村安孝、池田直人、望月美聡、曽根美由紀、坪井声示、林 秀樹、伊藤邦彦、小菅和仁、山田 浩、松山耐至エタネルセプト25mg皮下注シリンジ週2回投与から50mg皮下注シリンジ週1回投与に変更した患者における有用性の評価 Inoue K, Ando N, Suzuki E, Hayashi H, Tsuji D, Itoh K.
Genotype distributions and allele frequencies of possible major depressive disorder-associated single nucleotide polymorphisms, cyclic adenosine monophosphate response element binding protein 1 rs4675690 and Piccolo rs2522833, in a Japanese population
Biol. Pharm. Bull., 35, 265-268 (2012)
Tsuji D, Kim YI, Taku K, Nakagaki S, Ikematsu Y, Tsubota H, Maeda M, Hashimoto N, Kimura M, Daimon T.Comparative trial of two intravenous doses of granisetron (1 versus 3 mg) in the prevention of chemotherapy-induced acute emesis: a double-blind, randomized, non-inferiority trial
Support Care Cancer, 20, 1057-1064 (2012)
Hayashi H, Tazoe Y, Horino M, Fujimaki-Katoh C, Tsuboi S, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh K.An artifact derived from pseudogene led to the discovery of micro RNA binding site polymorphism in 3′-untranslated region of human dihydrofolate reductase gene
Drug Metab. Pharmacokinet., 27, 263-267 (2012)
伊藤邦彦臨床薬学演習のコンテンツ作成における大学連携のメリット
2011
Yoshida A, Hirooka Y, Sugata Y, Nitta M, Manabe T, Ido S, Murakami K, Saha RK, Suzuki T, Ohshima M, Yoshida A, Itoh K, Shimizu K, Oku N, Furuta T, Asakawa T, Wakimoto T, Kan T
Concise synthesis of catechin probes enabling analysis and imaging of EGCg
地域医療を支え，薬剤師の意欲を高めるリカレント教育と大学の役割
Concise synthesis of catechin probes enabling analysis and imaging of EGCg
Chem. Commun., 47, 1794-1796 (2011)
賀川義之, 野口博司, 並木徳之, 林 秀樹, 小菅和仁地域医療を支え，薬剤師の意欲を高めるリカレント教育と大学の役割
2010
Urushibata Y, Itoh K, Ohshima M, Seto Y
Generation of Fab Fragment-like Molecular Recognition Proteins against Staphylococcal Enterotoxin B by Phage Display Technology
Generation of AcGFP-labeled single-chain Fv against 5-methyl 2′-deoxycytidine from a hyperimmunized mouse using phage display technology
Dihydrofolate reductase gene intronic 19-bp deletion polymorphisms in a Japanese population
ワルファリン服用患者における出血リスクに対するプロトンポンプ阻害薬併用の影響
WarfarinとビタミンKの相互作用に関する文献的調査
Generation of a recombinant single-chain variable fragment (scFv) targeting 5-methyl-2'-deoxcytidine
Generation of Fab Fragment-like Molecular Recognition Proteins against Staphylococcal Enterotoxin B by Phage Display Technology
Clin. Vaccine Immunol., 17, 1708-1717 (2010)
Ohshima M, Inoue K, Hayashi H, Tsuji D, Mizugaki M, Itoh KGeneration of AcGFP-labeled single-chain Fv against 5-methyl 2′-deoxycytidine from a hyperimmunized mouse using phage display technology
Protein Engineering, Design & Selection, 23, 881-888 (2010)
Hayashi H, Horino M, Morishita M, Tazoe Y, Tsuboi S, Matsuyama T, Kosuge K, Yamada H, Tsuji D, Inoue K, Itoh KDihydrofolate reductase gene intronic 19-bp deletion polymorphisms in a Japanese population
Drug Metab. Pharmacokinet., 25, 516-518 (2010)
坂和園子, 林 秀樹, 吉澤美沙, 堀野雅人, 森脇秀明, 秋本剛秀, 土井 修, 井上和幸, 辻 大樹, 河原崎貴伯, 伊藤邦彦ワルファリン服用患者における出血リスクに対するプロトンポンプ阻害薬併用の影響
日本病院薬剤師会雑誌, 46, 535-538 (2010)
藤野知美, 伊藤由彦, 滝 優子, 柿澤希実, 尾上誠良, 今井康之, 奥 直人, 野口博司, 伊藤邦彦, 小林裕和, 大橋典男, 合田敏尚, 木苗直秀, 梅垣敬三, 渡邉祐司, 山田静雄WarfarinとビタミンKの相互作用に関する文献的調査
臨床薬理, 41, 43-50 (2010)
Ohshima M, Tadakuma T, Hayashi H, Inoue K, Itoh KGeneration of a recombinant single-chain variable fragment (scFv) targeting 5-methyl-2'-deoxcytidine
2009
林 秀樹, 神戸宏憲, 吉川俊博, 大門貴志, 鍋田いづみ, 木村 緑, 山田浩, 浮島美之, 井上和幸, 河原崎貴伯, 伊藤邦彦
がん化学療法における携帯型ディスポーザブル注入ポンプの流速変動因子の解析
Effect of VKORC1 -1639 G>A polymorphism, body weight, age, and serum albumin alterationson warfarin response in Japanese patients
Genetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis
Plasma total homocysteine level and methylenetetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis Itoh K, Ohshima M, Sonobe M, Saito M, Yoshida A, Hayashi H, Inoue K, Masuko T
Antibody epitope peptides as a potent inducer of IgG antibodies againstCD98 oncoprotein.
がん化学療法における携帯型ディスポーザブル注入ポンプの流速変動因子の解析
日本病院薬剤師会雑誌, 45, 821-824 (2009)
Yoshizawa M, Hayashi H, Tashiro Y, Sakawa S, Moriwaki H, Akimoto T, Doi O, Kimura M, Kawarasaki Y, Inoue K, Itoh KEffect of VKORC1 -1639 G>A polymorphism, body weight, age, and serum albumin alterationson warfarin response in Japanese patients
Thromb. Res., 124, 161-166 (2009)
Hayashi H, Fujimaki C, Daimon T, Tsuboi S, Matsuyama T, Itoh KGenetic polymorphisms in folate pathway enzymes as a possible marker for predicting the outcome of methotrexate therapy in Japanese patients with rheumatoid arthritis
J. Clin. Pharm. Ther., 34, 355-361 (2009)
Fujimaki C, Hayashi H, Tsuboi S, Matsuyama T, Kosuge K, Yamada H, Inoue K, Itoh KPlasma total homocysteine level and methylenetetrahydrofolate reductase 677C>T genetic polymorphism in Japanese patients with rheumatoid arthritis Itoh K, Ohshima M, Sonobe M, Saito M, Yoshida A, Hayashi H, Inoue K, Masuko T
Antibody epitope peptides as a potent inducer of IgG antibodies againstCD98 oncoprotein.
2008
Hayashi H, Fujimaki C, Tsuboi S, Matsuyama T, Daimon T,Itoh K
Application of fluorescence polarization immunoassay for determination of methotrexate-polyglutamates in rheumatoid arthritis patients.
Influence of the tyrosine hydroxylase val81met polymorphism and catechol-O-methyltransferaseval58met polymorphism on the antidepressant effect of milnacipran.
Application of fluorescence polarization immunoassay for determination of methotrexate-polyglutamates in rheumatoid arthritis patients.
Tohoku J. Exp. Med., 215, 95-101 (2008)
Yoshida K., Higuchi H., Takahashi H., Kamata M., Sato K., Inoue K., Suzuki T., Itoh K., Ozaki, N.Influence of the tyrosine hydroxylase val81met polymorphism and catechol-O-methyltransferaseval58met polymorphism on the antidepressant effect of milnacipran.
2007
Itoh K.
Development of diagnostically and therapeutically useful human antibody medicines by phage display system
No association of the G1287A polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population
Identification of cell proliferation-associated epitope on CD98 oncoprotein using phage display random peptide library
The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine
Cloning and expression of two human recombinant monoclonal Fab fragments specific for EBV viral capsid antigen
Genetic Polymorphism of C452T (T127I) in Human γ-Glutamyl Hydrolase in a Japanese Population
Development of diagnostically and therapeutically useful human antibody medicines by phage display system
Yakugaku Zasshi, 127, 43-53 (2007)
Inoue K, Itoh K, Yoshida K, Higuchi H, Kamata M, Takahashi H, Shimizu T, Suzuki TNo association of the G1287A polymorphism in the norepinephrine transporter gene and susceptibility to major depressive disorder in a Japanese population
Biol. Pharm. Bull. 30, 1996-1998 (2007)
Itoh K, Inoue K, Hayashi H, Suzuki T, Masuko T.Identification of cell proliferation-associated epitope on CD98 oncoprotein using phage display random peptide library
Cancer Sci. 98 1696-1700 (2007)
Yoshida K, Higuchi H, Kamata M, Takahashi H, Inoue K, Suzuki T, Itoh K, Ozaki N.The G196A polymorphism of the brain-derived neurotrophic factor gene and the antidepressant effect of milnacipran and fluvoxamine
J. Psychopharmacol. 21, 650-656 (2007)
Dong L., Masaki Y, Takegami T, Kawanami T, Itoh K, Jin Z-X, Huang C-R, Tong X-P, Fukushima T, Tanaka M, Sawaki T, Sakai T, Sugai S, Ozaki T, Hirose Y, Umehara H.Cloning and expression of two human recombinant monoclonal Fab fragments specific for EBV viral capsid antigen
Int. Immunol. 19, 331-336 (2007)
Hayashi H, Fujimaki C, Inoue K, Suzuki T, Itoh K.Genetic Polymorphism of C452T (T127I) in Human γ-Glutamyl Hydrolase in a Japanese Population
2006
Watanabe M, Kazuta Y, Hayashi H, Yamada S, Matsuda A, Shuto S.
Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure
Urinary pseudouridine in patients with lymphoma: Comparison with other clinical parameters
蛍光偏光免疫測定(FPIA)法による血中薬物濃度測定に及ぼす総ビリルビンの影響
Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H3 and/or H4 receptor antagonists with an imidazolylcyclopropane structure
J. Med. Chem., 49, 5587-5596 (2006)
Masaki Y, Itoh K, Sawaki T, Karasawa H, Kawanami T, Fukushima T, Kawabata H, Wano Y, Hirose Y, Suzuki T, Sugai S, Umehara H.Urinary pseudouridine in patients with lymphoma: Comparison with other clinical parameters
Clin. Chim. Acta., 371, 148-151 (2006)
井上和幸，伊藤邦彦，佐藤悦子，多田 均，鈴木敏夫蛍光偏光免疫測定(FPIA)法による血中薬物濃度測定に及ぼす総ビリルビンの影響
日本病院薬剤師会雑誌, 42, 651-653 (2006)
後発医薬品採用のための品質評価 －マレイン酸エナラプリル錠における検討－
医療薬学，32, 306-313 (2006)
2005
Seki, Y., Hayashi, K., Itoh, K., Mizugaki, M., Saitou, M. and Matsui, Y.
Extensive and orderly reprogramming of genome-wide hromatin modifications associated with specification and early development of germ cells in mice
秋田県における急性脳症の発生状況と原因究明への中毒学的アプローチ
Extensive and orderly reprogramming of genome-wide hromatin modifications associated with specification and early development of germ cells in mice
Dev. Biol., 278, 440-458 (2005)
権守邦夫，渡部加奈子，伊藤邦彦，鳥海良寛，武藤 一，豊島 至，佐藤 滋，吉岡尚文，鈴木 修秋田県における急性脳症の発生状況と原因究明への中毒学的アプローチ
中毒研究，18, 249-255 (2005)
